291 related articles for article (PubMed ID: 15034620)
1. Synthesis and evaluation of analogues of 10H-indolo[3,2-b]quinoline as G-quadruplex stabilising ligands and potential inhibitors of the enzyme telomerase.
Guyen B; Schultes CM; Hazel P; Mann J; Neidle S
Org Biomol Chem; 2004 Apr; 2(7):981-8. PubMed ID: 15034620
[TBL] [Abstract][Full Text] [Related]
2. 5-N-methylated quindoline derivatives as telomeric g-quadruplex stabilizing ligands: effects of 5-N positive charge on quadruplex binding affinity and cell proliferation.
Lu YJ; Ou TM; Tan JH; Hou JQ; Shao WY; Peng D; Sun N; Wang XD; Wu WB; Bu XZ; Huang ZS; Ma DL; Wong KY; Gu LQ
J Med Chem; 2008 Oct; 51(20):6381-92. PubMed ID: 18821749
[TBL] [Abstract][Full Text] [Related]
3. Synthesis and evaluation of quindoline derivatives as G-quadruplex inducing and stabilizing ligands and potential inhibitors of telomerase.
Zhou JL; Lu YJ; Ou TM; Zhou JM; Huang ZS; Zhu XF; Du CJ; Bu XZ; Ma L; Gu LQ; Li YM; Chan AS
J Med Chem; 2005 Nov; 48(23):7315-21. PubMed ID: 16279791
[TBL] [Abstract][Full Text] [Related]
4. Isaindigotone derivatives: a new class of highly selective ligands for telomeric G-quadruplex DNA.
Tan JH; Ou TM; Hou JQ; Lu YJ; Huang SL; Luo HB; Wu JY; Huang ZS; Wong KY; Gu LQ
J Med Chem; 2009 May; 52(9):2825-35. PubMed ID: 19354252
[TBL] [Abstract][Full Text] [Related]
5. Senescence and telomere shortening induced by novel potent G-quadruplex interactive agents, quindoline derivatives, in human cancer cell lines.
Zhou JM; Zhu XF; Lu YJ; Deng R; Huang ZS; Mei YP; Wang Y; Huang WL; Liu ZC; Gu LQ; Zeng YX
Oncogene; 2006 Jan; 25(4):503-11. PubMed ID: 16170347
[TBL] [Abstract][Full Text] [Related]
6. Studies on the binding of 5-N-methylated quindoline derivative to human telomeric G-quadruplex.
Xu W; Tan JH; Chen SB; Hou JQ; Li D; Huang ZS; Gu LQ
Biochem Biophys Res Commun; 2011 Mar; 406(3):454-8. PubMed ID: 21333628
[TBL] [Abstract][Full Text] [Related]
7. Amide bond direction modulates G-quadruplex recognition and telomerase inhibition by 2,6 and 2,7 bis-substituted anthracenedione derivatives.
Zagotto G; Sissi C; Moro S; Dal Ben D; Parkinson GN; Fox KR; Neidle S; Palumbo M
Bioorg Med Chem; 2008 Jan; 16(1):354-61. PubMed ID: 17936629
[TBL] [Abstract][Full Text] [Related]
8. Trisubstituted acridine derivatives as potent and selective telomerase inhibitors.
Harrison RJ; Cuesta J; Chessari G; Read MA; Basra SK; Reszka AP; Morrell J; Gowan SM; Incles CM; Tanious FA; Wilson WD; Kelland LR; Neidle S
J Med Chem; 2003 Oct; 46(21):4463-76. PubMed ID: 14521409
[TBL] [Abstract][Full Text] [Related]
9. Fluorescence-based melting assays for studying quadruplex ligands.
De Cian A; Guittat L; Kaiser M; Saccà B; Amrane S; Bourdoncle A; Alberti P; Teulade-Fichou MP; Lacroix L; Mergny JL
Methods; 2007 Jun; 42(2):183-95. PubMed ID: 17472900
[TBL] [Abstract][Full Text] [Related]
10. Synthesis and in vitro antiproliferative activity of new 11-aminoalkylamino-substituted 5H- and 6H-indolo[2,3-b]quinolines; structure-activity relationships of neocryptolepines and 6-methyl congeners.
Wang L; Switalska M; Mei ZW; Lu WJ; Takahara Y; Feng XW; El-Sayed Iel-T; Wietrzyk J; Inokuchi T
Bioorg Med Chem; 2012 Aug; 20(15):4820-9. PubMed ID: 22748378
[TBL] [Abstract][Full Text] [Related]
11. 9-Substituted berberine derivatives as G-quadruplex stabilizing ligands in telomeric DNA.
Zhang WJ; Ou TM; Lu YJ; Huang YY; Wu WB; Huang ZS; Zhou JL; Wong KY; Gu LQ
Bioorg Med Chem; 2007 Aug; 15(16):5493-501. PubMed ID: 17574421
[TBL] [Abstract][Full Text] [Related]
12. Trisubstituted acridines as G-quadruplex telomere targeting agents. Effects of extensions of the 3,6- and 9-side chains on quadruplex binding, telomerase activity, and cell proliferation.
Moore MJ; Schultes CM; Cuesta J; Cuenca F; Gunaratnam M; Tanious FA; Wilson WD; Neidle S
J Med Chem; 2006 Jan; 49(2):582-99. PubMed ID: 16420044
[TBL] [Abstract][Full Text] [Related]
13. Turning off transcription of the bcl-2 gene by stabilizing the bcl-2 promoter quadruplex with quindoline derivatives.
Wang XD; Ou TM; Lu YJ; Li Z; Xu Z; Xi C; Tan JH; Huang SL; An LK; Li D; Gu LQ; Huang ZS
J Med Chem; 2010 Jun; 53(11):4390-8. PubMed ID: 20481493
[TBL] [Abstract][Full Text] [Related]
14. Detection of telomerase inhibitors based on g-quadruplex ligands by a modified telomeric repeat amplification protocol assay.
Gomez D; Mergny JL; Riou JF
Cancer Res; 2002 Jun; 62(12):3365-8. PubMed ID: 12067975
[TBL] [Abstract][Full Text] [Related]
15. Specific interactions with intra- and intermolecular G-quadruplex DNA structures by hydrosoluble coronene derivatives: a new class of telomerase inhibitors.
Franceschin M; Alvino A; Casagrande V; Mauriello C; Pascucci E; Savino M; Ortaggi G; Bianco A
Bioorg Med Chem; 2007 Feb; 15(4):1848-58. PubMed ID: 17150364
[TBL] [Abstract][Full Text] [Related]
16. Synthesis and biological evaluation of novel 4,5-bis(dialkylaminoalkyl)-substituted acridines as potent telomeric G-quadruplex ligands.
Laronze-Cochard M; Kim YM; Brassart B; Riou JF; Laronze JY; Sapi J
Eur J Med Chem; 2009 Oct; 44(10):3880-8. PubMed ID: 19467742
[TBL] [Abstract][Full Text] [Related]
17. Biological evaluation of omega-(dialkylamino)alkyl derivatives of 6H-indolo[2,3-b]quinoline--novel cytotoxic DNA topoisomerase II inhibitors.
Godlewska J; Luniewski W; Zagrodzki B; Kaczmarek L; Bielawska-Pohl A; Dus D; Wietrzyk J; Opolski A; Siwko M; Jaromin A; Jakubiak A; Kozubek A; Peczyñska-Czoch W
Anticancer Res; 2005; 25(4):2857-68. PubMed ID: 16080538
[TBL] [Abstract][Full Text] [Related]
18. The recognition of higher-order G-quadruplex by chiral cyclic-helicene molecules.
Xu Y; Yamazaki S; Osuga H; Sugiyama H
Nucleic Acids Symp Ser (Oxf); 2006; (50):183-4. PubMed ID: 17150878
[TBL] [Abstract][Full Text] [Related]
19. Tri- and tetra-substituted naphthalene diimides as potent G-quadruplex ligands.
Cuenca F; Greciano O; Gunaratnam M; Haider S; Munnur D; Nanjunda R; Wilson WD; Neidle S
Bioorg Med Chem Lett; 2008 Mar; 18(5):1668-73. PubMed ID: 18243701
[TBL] [Abstract][Full Text] [Related]
20. Affinity and selectivity of G4 ligands measured by FRET.
De Cian A; Guittat L; Shin-ya K; Riou JF; Mergny JL
Nucleic Acids Symp Ser (Oxf); 2005; (49):235-6. PubMed ID: 17150720
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]