BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

447 related articles for article (PubMed ID: 15039704)

  • 1. Structural basis for recruitment of the ATPase activator Aha1 to the Hsp90 chaperone machinery.
    Meyer P; Prodromou C; Liao C; Hu B; Roe SM; Vaughan CK; Vlasic I; Panaretou B; Piper PW; Pearl LH
    EMBO J; 2004 Mar; 23(6):1402-10. PubMed ID: 15039704
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Structural basis for recruitment of the ATPase activator Aha1 to the Hsp90 chaperone machinery.
    Meyer P; Prodromou C; Liao C; Hu B; Mark Roe S; Vaughan CK; Vlasic I; Panaretou B; Piper PW; Pearl LH
    EMBO J; 2004 Feb; 23(3):511-9. PubMed ID: 14739935
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Aha1 binds to the middle domain of Hsp90, contributes to client protein activation, and stimulates the ATPase activity of the molecular chaperone.
    Lotz GP; Lin H; Harst A; Obermann WM
    J Biol Chem; 2003 May; 278(19):17228-35. PubMed ID: 12604615
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Co-chaperone regulation of conformational switching in the Hsp90 ATPase cycle.
    Siligardi G; Hu B; Panaretou B; Piper PW; Pearl LH; Prodromou C
    J Biol Chem; 2004 Dec; 279(50):51989-98. PubMed ID: 15466438
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A chemical compound inhibiting the Aha1-Hsp90 chaperone complex.
    Stiegler SC; Rübbelke M; Korotkov VS; Weiwad M; John C; Fischer G; Sieber SA; Sattler M; Buchner J
    J Biol Chem; 2017 Oct; 292(41):17073-17083. PubMed ID: 28851842
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A novel C-terminal homologue of Aha1 co-chaperone binds to heat shock protein 90 and stimulates its ATPase activity in Entamoeba histolytica.
    Singh M; Shah V; Tatu U
    J Mol Biol; 2014 Apr; 426(8):1786-98. PubMed ID: 24486610
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Asymmetric activation of the hsp90 dimer by its cochaperone aha1.
    Retzlaff M; Hagn F; Mitschke L; Hessling M; Gugel F; Kessler H; Richter K; Buchner J
    Mol Cell; 2010 Feb; 37(3):344-54. PubMed ID: 20159554
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Hsp90 cochaperone Aha1 is a negative regulator of the Saccharomyces MAL activator and acts early in the chaperone activation pathway.
    Ran F; Gadura N; Michels CA
    J Biol Chem; 2010 Apr; 285(18):13850-62. PubMed ID: 20177068
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Activation of the ATPase activity of hsp90 by the stress-regulated cochaperone aha1.
    Panaretou B; Siligardi G; Meyer P; Maloney A; Sullivan JK; Singh S; Millson SH; Clarke PA; Naaby-Hansen S; Stein R; Cramer R; Mollapour M; Workman P; Piper PW; Pearl LH; Prodromou C
    Mol Cell; 2002 Dec; 10(6):1307-18. PubMed ID: 12504007
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Integration of the accelerator Aha1 in the Hsp90 co-chaperone cycle.
    Li J; Richter K; Reinstein J; Buchner J
    Nat Struct Mol Biol; 2013 Mar; 20(3):326-31. PubMed ID: 23396352
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The conserved NxNNWHW motif in Aha-type co-chaperones modulates the kinetics of Hsp90 ATPase stimulation.
    Mercier R; Wolmarans A; Schubert J; Neuweiler H; Johnson JL; LaPointe P
    Nat Commun; 2019 Mar; 10(1):1273. PubMed ID: 30894538
    [TBL] [Abstract][Full Text] [Related]  

  • 12. A primate specific extra domain in the molecular chaperone Hsp90.
    Tripathi V; Obermann WM
    PLoS One; 2013; 8(8):e71856. PubMed ID: 23951259
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Cdc37 (cell division cycle 37) restricts Hsp90 (heat shock protein 90) motility by interaction with N-terminal and middle domain binding sites.
    Eckl JM; Rutz DA; Haslbeck V; Zierer BK; Reinstein J; Richter K
    J Biol Chem; 2013 May; 288(22):16032-42. PubMed ID: 23569206
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Structure and mechanism of the Hsp90 molecular chaperone machinery.
    Pearl LH; Prodromou C
    Annu Rev Biochem; 2006; 75():271-94. PubMed ID: 16756493
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The Co-chaperone Sba1 connects the ATPase reaction of Hsp90 to the progression of the chaperone cycle.
    Richter K; Walter S; Buchner J
    J Mol Biol; 2004 Oct; 342(5):1403-13. PubMed ID: 15364569
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Aha1 competes with Hop, p50 and p23 for binding to the molecular chaperone Hsp90 and contributes to kinase and hormone receptor activation.
    Harst A; Lin H; Obermann WM
    Biochem J; 2005 May; 387(Pt 3):789-96. PubMed ID: 15584899
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Modulation of the Hsp90 chaperone cycle by a stringent client protein.
    Lorenz OR; Freiburger L; Rutz DA; Krause M; Zierer BK; Alvira S; Cuéllar J; Valpuesta JM; Madl T; Sattler M; Buchner J
    Mol Cell; 2014 Mar; 53(6):941-53. PubMed ID: 24613341
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Regulation of Hsp90 ATPase activity by tetratricopeptide repeat (TPR)-domain co-chaperones.
    Prodromou C; Siligardi G; O'Brien R; Woolfson DN; Regan L; Panaretou B; Ladbury JE; Piper PW; Pearl LH
    EMBO J; 1999 Feb; 18(3):754-62. PubMed ID: 9927435
    [TBL] [Abstract][Full Text] [Related]  

  • 19. A mutation in the catalytic loop of Hsp90 specifically impairs ATPase stimulation by Aha1p, but not Hch1p.
    Horvat NK; Armstrong H; Lee BL; Mercier R; Wolmarans A; Knowles J; Spyracopoulos L; LaPointe P
    J Mol Biol; 2014 Jun; 426(12):2379-92. PubMed ID: 24726918
    [TBL] [Abstract][Full Text] [Related]  

  • 20. N-terminal residues regulate the catalytic efficiency of the Hsp90 ATPase cycle.
    Richter K; Reinstein J; Buchner J
    J Biol Chem; 2002 Nov; 277(47):44905-10. PubMed ID: 12235160
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 23.