BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

208 related articles for article (PubMed ID: 15044622)

  • 1. Interactions of nucleoside analogs, caffeine, and nicotine with human concentrative nucleoside transporters 1 and 2 stably produced in a transport-defective human cell line.
    Lang TT; Young JD; Cass CE
    Mol Pharmacol; 2004 Apr; 65(4):925-33. PubMed ID: 15044622
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Acquisition of human concentrative nucleoside transporter 2 (hcnt2) activity by gene transfer confers sensitivity to fluoropyrimidine nucleosides in drug-resistant leukemia cells.
    Lang TT; Selner M; Young JD; Cass CE
    Mol Pharmacol; 2001 Nov; 60(5):1143-52. PubMed ID: 11641443
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Molecular requirements of the human nucleoside transporters hCNT1, hCNT2, and hENT1.
    Chang C; Swaan PW; Ngo LY; Lum PY; Patil SD; Unadkat JD
    Mol Pharmacol; 2004 Mar; 65(3):558-70. PubMed ID: 14978234
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Uridine binding and transportability determinants of human concentrative nucleoside transporters.
    Zhang J; Smith KM; Tackaberry T; Visser F; Robins MJ; Nielsen LP; Nowak I; Karpinski E; Baldwin SA; Young JD; Cass CE
    Mol Pharmacol; 2005 Sep; 68(3):830-9. PubMed ID: 15955867
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Interaction of fused-pyrimidine nucleoside analogs with human concentrative nucleoside transporters: High-affinity inhibitors of human concentrative nucleoside transporter 1.
    Damaraju VL; Smith KM; Mowles D; Nowak I; Karpinski E; Young JD; Robins MJ; Cass CE
    Biochem Pharmacol; 2011 Jan; 81(1):82-90. PubMed ID: 20854794
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Role of human nucleoside transporters in the cellular uptake of two inhibitors of IMP dehydrogenase, tiazofurin and benzamide riboside.
    Damaraju VL; Visser F; Zhang J; Mowles D; Ng AM; Young JD; Jayaram HN; Cass CE
    Mol Pharmacol; 2005 Jan; 67(1):273-9. PubMed ID: 15486050
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Cation coupling properties of human concentrative nucleoside transporters hCNT1, hCNT2 and hCNT3.
    Smith KM; Slugoski MD; Cass CE; Baldwin SA; Karpinski E; Young JD
    Mol Membr Biol; 2007; 24(1):53-64. PubMed ID: 17453413
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Uridine binding motifs of human concentrative nucleoside transporters 1 and 3 produced in Saccharomyces cerevisiae.
    Zhang J; Visser F; Vickers MF; Lang T; Robins MJ; Nielsen LP; Nowak I; Baldwin SA; Young JD; Cass CE
    Mol Pharmacol; 2003 Dec; 64(6):1512-20. PubMed ID: 14645682
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The role of human nucleoside transporters in cellular uptake of 4'-thio-beta-D-arabinofuranosylcytosine and beta-D-arabinosylcytosine.
    Clarke ML; Damaraju VL; Zhang J; Mowles D; Tackaberry T; Lang T; Smith KM; Young JD; Tomkinson B; Cass CE
    Mol Pharmacol; 2006 Jul; 70(1):303-10. PubMed ID: 16617163
    [TBL] [Abstract][Full Text] [Related]  

  • 10. A comparison of the transportability, and its role in cytotoxicity, of clofarabine, cladribine, and fludarabine by recombinant human nucleoside transporters produced in three model expression systems.
    King KM; Damaraju VL; Vickers MF; Yao SY; Lang T; Tackaberry TE; Mowles DA; Ng AM; Young JD; Cass CE
    Mol Pharmacol; 2006 Jan; 69(1):346-53. PubMed ID: 16234483
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Transport of physiological nucleosides and anti-viral and anti-neoplastic nucleoside drugs by recombinant Escherichia coli nucleoside-H(+) cotransporter (NupC) produced in Xenopus laevis oocytes.
    Loewen SK; Yao SY; Slugoski MD; Mohabir NN; Turner RJ; Mackey JR; Weiner JH; Gallagher MP; Henderson PJ; Baldwin SA; Cass CE; Young JD
    Mol Membr Biol; 2004; 21(1):1-10. PubMed ID: 14668133
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Electrophysiological characterization of a recombinant human Na+-coupled nucleoside transporter (hCNT1) produced in Xenopus oocytes.
    Smith KM; Ng AM; Yao SY; Labedz KA; Knaus EE; Wiebe LI; Cass CE; Baldwin SA; Chen XZ; Karpinski E; Young JD
    J Physiol; 2004 Aug; 558(Pt 3):807-23. PubMed ID: 15194733
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Electrophysiological analysis of the substrate selectivity of a sodium-coupled nucleoside transporter (rCNT1) expressed in Xenopus laevis oocytes.
    Dresser MJ; Gerstin KM; Gray AT; Loo DD; Giacomini KM
    Drug Metab Dispos; 2000 Sep; 28(9):1135-40. PubMed ID: 10950861
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Molecular cloning, functional expression and chromosomal localization of a cDNA encoding a human Na+/nucleoside cotransporter (hCNT2) selective for purine nucleosides and uridine.
    Ritzel MW; Yao SY; Ng AM; Mackey JR; Cass CE; Young JD
    Mol Membr Biol; 1998; 15(4):203-11. PubMed ID: 10087507
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Functional characterization of a human purine-selective, Na+-dependent nucleoside transporter (hSPNT1) in a mammalian expression system.
    Schaner ME; Wang J; Zhang L; Su SF; Gerstin KM; Giacomini KM
    J Pharmacol Exp Ther; 1999 Jun; 289(3):1487-91. PubMed ID: 10336543
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Functional expression and characterization of a sodium-dependent nucleoside transporter hCNT2 cloned from human duodenum.
    Shin HC; Landowski CP; Sun D; Vig BS; Kim I; Mittal S; Lane M; Rosania G; Drach JC; Amidon GL
    Biochem Biophys Res Commun; 2003 Aug; 307(3):696-703. PubMed ID: 12893280
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Identification of amino acid residues responsible for the pyrimidine and purine nucleoside specificities of human concentrative Na(+) nucleoside cotransporters hCNT1 and hCNT2.
    Loewen SK; Ng AM; Yao SY; Cass CE; Baldwin SA; Young JD
    J Biol Chem; 1999 Aug; 274(35):24475-84. PubMed ID: 10455109
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The nucleoside transport proteins, NupC and NupG, from Escherichia coli: specific structural motifs necessary for the binding of ligands.
    Patching SG; Baldwin SA; Baldwin AD; Young JD; Gallagher MP; Henderson PJ; Herbert RB
    Org Biomol Chem; 2005 Feb; 3(3):462-70. PubMed ID: 15678184
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Transepithelial fluxes of adenosine and 2'-deoxyadenosine across human renal proximal tubule cells: roles of nucleoside transporters hENT1, hENT2, and hCNT3.
    Elwi AN; Damaraju VL; Kuzma ML; Mowles DA; Baldwin SA; Young JD; Sawyer MB; Cass CE
    Am J Physiol Renal Physiol; 2009 Jun; 296(6):F1439-51. PubMed ID: 19297449
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Specific mutations in transmembrane helix 8 of human concentrative Na+/nucleoside cotransporter hCNT1 affect permeant selectivity and cation coupling.
    Slugoski MD; Loewen SK; Ng AM; Smith KM; Yao SY; Karpinski E; Cass CE; Baldwin SA; Young JD
    Biochemistry; 2007 Feb; 46(6):1684-93. PubMed ID: 17279631
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.