These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

168 related articles for article (PubMed ID: 15049684)

  • 1. Crystal structures of an intrinsically active cholera toxin mutant yield insight into the toxin activation mechanism.
    O'Neal CJ; Amaya EI; Jobling MG; Holmes RK; Hol WG
    Biochemistry; 2004 Apr; 43(13):3772-82. PubMed ID: 15049684
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Exploration of the GM1 receptor-binding site of heat-labile enterotoxin and cholera toxin by phenyl-ring-containing galactose derivatives.
    Fan E; Merritt EA; Zhang Z; Pickens JC; Roach C; Ahn M; Hol WG
    Acta Crystallogr D Biol Crystallogr; 2001 Feb; 57(Pt 2):201-12. PubMed ID: 11173465
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Galactose-binding site in Escherichia coli heat-labile enterotoxin (LT) and cholera toxin (CT).
    Merritt EA; Sixma TK; Kalk KH; van Zanten BA; Hol WG
    Mol Microbiol; 1994 Aug; 13(4):745-53. PubMed ID: 7997185
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Crystal structure of a new heat-labile enterotoxin, LT-IIb.
    van den Akker F; Sarfaty S; Twiddy EM; Connell TD; Holmes RK; Hol WG
    Structure; 1996 Jun; 4(6):665-78. PubMed ID: 8805549
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The Arg7Lys mutant of heat-labile enterotoxin exhibits great flexibility of active site loop 47-56 of the A subunit.
    van den Akker F; Merritt EA; Pizza M; Domenighini M; Rappuoli R; Hol WG
    Biochemistry; 1995 Sep; 34(35):10996-1004. PubMed ID: 7669757
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Structural foundation for the design of receptor antagonists targeting Escherichia coli heat-labile enterotoxin.
    Merritt EA; Sarfaty S; Feil IK; Hol WG
    Structure; 1997 Nov; 5(11):1485-99. PubMed ID: 9384564
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Structural diversity in a conserved cholera toxin epitope involved in ganglioside binding.
    Shoham M; Scherf T; Anglister J; Levitt M; Merritt EA; Hol WG
    Protein Sci; 1995 May; 4(5):841-8. PubMed ID: 7545048
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Crystal structure of a non-toxic mutant of heat-labile enterotoxin, which is a potent mucosal adjuvant.
    van den Akker F; Pizza M; Rappuoli R; Hol WG
    Protein Sci; 1997 Dec; 6(12):2650-4. PubMed ID: 9416617
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Protein engineering studies of A-chain loop 47-56 of Escherichia coli heat-labile enterotoxin point to a prominent role of this loop for cytotoxicity.
    Feil IK; Reddy R; de Haan L; Merritt EA; van den Akker F; Storm DR; Hol WG
    Mol Microbiol; 1996 May; 20(4):823-32. PubMed ID: 8793878
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Refined structure of Escherichia coli heat-labile enterotoxin, a close relative of cholera toxin.
    Sixma TK; Kalk KH; van Zanten BA; Dauter Z; Kingma J; Witholt B; Hol WG
    J Mol Biol; 1993 Apr; 230(3):890-918. PubMed ID: 8478941
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Structural studies of receptor binding by cholera toxin mutants.
    Merritt EA; Sarfaty S; Jobling MG; Chang T; Holmes RK; Hirst TR; Hol WG
    Protein Sci; 1997 Jul; 6(7):1516-28. PubMed ID: 9232653
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Novel binding site identified in a hybrid between cholera toxin and heat-labile enterotoxin: 1.9 A crystal structure reveals the details.
    Holmner A; Lebens M; Teneberg S; Angström J; Okvist M; Krengel U
    Structure; 2004 Sep; 12(9):1655-67. PubMed ID: 15341730
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Crystal structures exploring the origins of the broader specificity of escherichia coli heat-labile enterotoxin compared to cholera toxin.
    Holmner A; Mackenzie A; Okvist M; Jansson L; Lebens M; Teneberg S; Krengel U
    J Mol Biol; 2011 Feb; 406(3):387-402. PubMed ID: 21168418
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Crystal structure of heat-labile enterotoxin from Escherichia coli with increased thermostability introduced by an engineered disulfide bond in the A subunit.
    van den Akker F; Feil IK; Roach C; Platas AA; Merritt EA; Hol WG
    Protein Sci; 1997 Dec; 6(12):2644-9. PubMed ID: 9416616
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The three-dimensional crystal structure of cholera toxin.
    Zhang RG; Scott DL; Westbrook ML; Nance S; Spangler BD; Shipley GG; Westbrook EM
    J Mol Biol; 1995 Aug; 251(4):563-73. PubMed ID: 7658473
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Structure of partially-activated E. coli heat-labile enterotoxin (LT) at 2.6 A resolution.
    Merritt EA; Pronk SE; Sixma TK; Kalk KH; van Zanten BA; Hol WG
    FEBS Lett; 1994 Jan; 337(1):88-92. PubMed ID: 8276119
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Structure-based discovery of a pore-binding ligand: towards assembly inhibitors for cholera and related AB5 toxins.
    Hovey BT; Verlinde CL; Merritt EA; Hol WG
    J Mol Biol; 1999 Jan; 285(3):1169-78. PubMed ID: 9887271
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Stepwise transplantation of an active site loop between heat-labile enterotoxins LT-II and LT-I and characterization of the obtained hybrid toxins.
    Feil IK; Platas AA; van den Akker F; Reddy R; Merritt EA; Storm DR; Hol WG
    Protein Eng; 1998 Nov; 11(11):1103-9. PubMed ID: 9876933
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Holotoxin disassembly by protein disulfide isomerase is less efficient for Escherichia coli heat-labile enterotoxin than cholera toxin.
    Serrano A; Guyette JL; Heim JB; Taylor M; Cherubin P; Krengel U; Teter K; Tatulian SA
    Sci Rep; 2022 Jan; 12(1):34. PubMed ID: 34997016
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Structure-based exploration of the ganglioside GM1 binding sites of Escherichia coli heat-labile enterotoxin and cholera toxin for the discovery of receptor antagonists.
    Minke WE; Roach C; Hol WG; Verlinde CL
    Biochemistry; 1999 May; 38(18):5684-92. PubMed ID: 10231518
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.