BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

162 related articles for article (PubMed ID: 15051055)

  • 1. Bioactivation of carbamate-based 20(S)-camptothecin prodrugs.
    Pessah N; Reznik M; Shamis M; Yantiri F; Xin H; Bowdish K; Shomron N; Ast G; Shabat D
    Bioorg Med Chem; 2004 Apr; 12(8):1859-66. PubMed ID: 15051055
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Bioactivation of self-immolative dendritic prodrugs by catalytic antibody 38C2.
    Shamis M; Lode HN; Shabat D
    J Am Chem Soc; 2004 Feb; 126(6):1726-31. PubMed ID: 14871103
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Development of albumin-binding camptothecin prodrugs using a Peptide positional scanning library.
    Schmid B; Warnecke A; Fichtner I; Jung M; Kratz F
    Bioconjug Chem; 2007; 18(6):1786-99. PubMed ID: 17915955
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Synthesis and evaluation of nitroheterocyclic carbamate prodrugs for use with nitroreductase-mediated gene-directed enzyme prodrug therapy.
    Hay MP; Anderson RF; Ferry DM; Wilson WR; Denny WA
    J Med Chem; 2003 Dec; 46(25):5533-45. PubMed ID: 14640560
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Albumin-binding prodrugs of camptothecin and doxorubicin with an Ala-Leu-Ala-Leu-linker that are cleaved by cathepsin B: synthesis and antitumor efficacy.
    Schmid B; Chung DE; Warnecke A; Fichtner I; Kratz F
    Bioconjug Chem; 2007; 18(3):702-16. PubMed ID: 17378599
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Bioreduction activated prodrugs of camptothecin: molecular design, synthesis, activation mechanism and hypoxia selective cytotoxicity.
    Zhang Z; Tanabe K; Hatta H; Nishimoto S
    Org Biomol Chem; 2005 May; 3(10):1905-10. PubMed ID: 15889173
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Synthesis and activity of a folate peptide camptothecin prodrug.
    Henne WA; Doorneweerd DD; Hilgenbrink AR; Kularatne SA; Low PS
    Bioorg Med Chem Lett; 2006 Oct; 16(20):5350-5. PubMed ID: 16901694
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Enzymatic activation of second-generation dendritic prodrugs: Conjugation of self-immolative dendrimers with poly(ethylene glycol) via click chemistry.
    Gopin A; Ebner S; Attali B; Shabat D
    Bioconjug Chem; 2006; 17(6):1432-40. PubMed ID: 17105221
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Activation of a camptothecin prodrug by specific carboxylesterases as predicted by quantitative structure-activity relationship and molecular docking studies.
    Yoon KJ; Krull EJ; Morton CL; Bornmann WG; Lee RE; Potter PM; Danks MK
    Mol Cancer Ther; 2003 Nov; 2(11):1171-81. PubMed ID: 14617791
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Structure-activity relationships for 4-nitrobenzyl carbamates of 5-aminobenz[e]indoline minor groove alkylating agents as prodrugs for GDEPT in conjunction with E. coli nitroreductase.
    Hay MP; Atwell GJ; Wilson WR; Pullen SM; Denny WA
    J Med Chem; 2003 Jun; 46(12):2456-66. PubMed ID: 12773049
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Remarkable drug-release enhancement with an elimination-based AB3 self-immolative dendritic amplifier.
    Sagi A; Segal E; Satchi-Fainaro R; Shabat D
    Bioorg Med Chem; 2007 Jun; 15(11):3720-7. PubMed ID: 17416532
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Camptothecin-7-yl-methanthiole: semisynthesis and biological evaluation.
    Christodoulou MS; Zunino F; Zuco V; Borrelli S; Comi D; Fontana G; Martinelli M; Lorens JB; Evensen L; Sironi M; Pieraccini S; Dalla Via L; Gia OM; Passarella D
    ChemMedChem; 2012 Dec; 7(12):2134-43. PubMed ID: 23086693
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Maleimide-oligo(ethylene glycol) derivatives of camptothecin as albumin-binding prodrugs: synthesis and antitumor efficacy.
    Warnecke A; Kratz F
    Bioconjug Chem; 2003; 14(2):377-87. PubMed ID: 12643748
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Nitrobenzylcarbamate prodrugs of cytotoxic acridines for potential use with nitroreductase gene-directed enzyme prodrug therapy.
    Asche C; Dumy P; Carrez D; Croisy A; Demeunynck M
    Bioorg Med Chem Lett; 2006 Apr; 16(7):1990-4. PubMed ID: 16442795
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Self-assembling nanowires of an amphiphilic camptothecin prodrug derived from homologous derivative conjugation.
    He D; Zhang W; Deng H; Huo S; Wang YF; Gong N; Deng L; Liang XJ; Dong A
    Chem Commun (Camb); 2016 Dec; 52(98):14145-14148. PubMed ID: 27869268
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Targeting the delivery of glycan-based paclitaxel prodrugs to cancer cells via glucose transporters.
    Lin YS; Tungpradit R; Sinchaikul S; An FM; Liu DZ; Phutrakul S; Chen ST
    J Med Chem; 2008 Dec; 51(23):7428-41. PubMed ID: 19053781
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The role of rat serum carboxylesterase in the activation of paclitaxel and camptothecin prodrugs.
    Senter PD; Marquardt H; Thomas BA; Hammock BD; Frank IS; Svensson HP
    Cancer Res; 1996 Apr; 56(7):1471-4. PubMed ID: 8603386
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The self-assembling camptothecin-tocopherol prodrug: An effective approach for formulating camptothecin.
    Lu J; Liu C; Wang P; Ghazwani M; Xu J; Huang Y; Ma X; Zhang P; Li S
    Biomaterials; 2015 Sep; 62():176-87. PubMed ID: 26057133
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Novel prodrugs of SN38 using multiarm poly(ethylene glycol) linkers.
    Zhao H; Rubio B; Sapra P; Wu D; Reddy P; Sai P; Martinez A; Gao Y; Lozanguiez Y; Longley C; Greenberger LM; Horak ID
    Bioconjug Chem; 2008 Apr; 19(4):849-59. PubMed ID: 18370417
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Nitroarylmethylcarbamate prodrugs of doxorubicin for use with nitroreductase gene-directed enzyme prodrug therapy.
    Hay MP; Wilson WR; Denny WA
    Bioorg Med Chem; 2005 Jun; 13(12):4043-55. PubMed ID: 15911317
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.