258 related articles for article (PubMed ID: 15051534)
21. Comparison of 17-dimethylaminoethylamino-17-demethoxy-geldanamycin (17DMAG) and 17-allylamino-17-demethoxygeldanamycin (17AAG) in vitro: effects on Hsp90 and client proteins in melanoma models.
Smith V; Sausville EA; Camalier RF; Fiebig HH; Burger AM
Cancer Chemother Pharmacol; 2005 Aug; 56(2):126-37. PubMed ID: 15841378
[TBL] [Abstract][Full Text] [Related]
22. The co-chaperone p23 arrests the Hsp90 ATPase cycle to trap client proteins.
McLaughlin SH; Sobott F; Yao ZP; Zhang W; Nielsen PR; Grossmann JG; Laue ED; Robinson CV; Jackson SE
J Mol Biol; 2006 Feb; 356(3):746-58. PubMed ID: 16403413
[TBL] [Abstract][Full Text] [Related]
23. ATPase inhibitors suppress actinomycin D-induced apoptosis in leukemia cells.
Shiono Y; Fujita Y; Oka S; Yamazaki Y
Anticancer Res; 2002; 22(5):2907-11. PubMed ID: 12530016
[TBL] [Abstract][Full Text] [Related]
24. 6-Alkylsalicylic acid analogues inhibit in vitro ATPase activity of heat shock protein 90.
Wu CZ; Moon AN; Choi O; Kang SY; Lee JJ; Lee D; Hwang BY; Kim YH; Lee HS; Hong YS
Arch Pharm Res; 2010 Dec; 33(12):1997-2001. PubMed ID: 21191765
[TBL] [Abstract][Full Text] [Related]
25. Some sulfonamide drugs inhibit ATPase activity of heat shock protein 90: investigation by docking simulation and experimental validation.
Sheikha GA; Al-Sha'er MA; Taha MO
J Enzyme Inhib Med Chem; 2011 Oct; 26(5):603-9. PubMed ID: 21190426
[TBL] [Abstract][Full Text] [Related]
26. Dihydroxylphenyl amides as inhibitors of the Hsp90 molecular chaperone.
Kung PP; Funk L; Meng J; Collins M; Zhou JZ; Johnson MC; Ekker A; Wang J; Mehta P; Yin MJ; Rodgers C; Davies JF; Bayman E; Smeal T; Maegley KA; Gehring MR
Bioorg Med Chem Lett; 2008 Dec; 18(23):6273-8. PubMed ID: 18929486
[TBL] [Abstract][Full Text] [Related]
27. Development of 17-allylamino-17-demethoxygeldanamycin hydroquinone hydrochloride (IPI-504), an anti-cancer agent directed against Hsp90.
Sydor JR; Normant E; Pien CS; Porter JR; Ge J; Grenier L; Pak RH; Ali JA; Dembski MS; Hudak J; Patterson J; Penders C; Pink M; Read MA; Sang J; Woodward C; Zhang Y; Grayzel DS; Wright J; Barrett JA; Palombella VJ; Adams J; Tong JK
Proc Natl Acad Sci U S A; 2006 Nov; 103(46):17408-13. PubMed ID: 17090671
[TBL] [Abstract][Full Text] [Related]
28. Anti-proliferative activity of heat shock protein (Hsp) 90 inhibitors via beta-catenin/TCF7L2 pathway in adult T cell leukemia cells.
Kurashina R; Ohyashiki JH; Kobayashi C; Hamamura R; Zhang Y; Hirano T; Ohyashiki K
Cancer Lett; 2009 Oct; 284(1):62-70. PubMed ID: 19464103
[TBL] [Abstract][Full Text] [Related]
29. Substrate transfer from the chaperone Hsp70 to Hsp90.
Wegele H; Wandinger SK; Schmid AB; Reinstein J; Buchner J
J Mol Biol; 2006 Feb; 356(3):802-11. PubMed ID: 16403523
[TBL] [Abstract][Full Text] [Related]
30. Heat shock protein 90 inhibition is cytotoxic to primary AML cells expressing mutant FLT3 and results in altered downstream signalling.
Al Shaer L; Walsby E; Gilkes A; Tonks A; Walsh V; Mills K; Burnett A; Rowntree C
Br J Haematol; 2008 May; 141(4):483-93. PubMed ID: 18373709
[TBL] [Abstract][Full Text] [Related]
31. Synthesis and biological activity of simplified denoviose-coumarins related to novobiocin as potent inhibitors of heat-shock protein 90 (hsp90).
Radanyi C; Le Bras G; Messaoudi S; Bouclier C; Peyrat JF; Brion JD; Marsaud V; Renoir JM; Alami M
Bioorg Med Chem Lett; 2008 Apr; 18(7):2495-8. PubMed ID: 18304811
[TBL] [Abstract][Full Text] [Related]
32. ATPase inhibitors of heat-shock protein 90, second season.
Janin YL
Drug Discov Today; 2010 May; 15(9-10):342-53. PubMed ID: 20230904
[TBL] [Abstract][Full Text] [Related]
33. A new approach for enhancing differential selectivity of drugs to cancer cells.
Duvvuri M; Konkar S; Hong KH; Blagg BS; Krise JP
ACS Chem Biol; 2006 Jun; 1(5):309-15. PubMed ID: 17163760
[TBL] [Abstract][Full Text] [Related]
34. 4,5-diarylisoxazole Hsp90 chaperone inhibitors: potential therapeutic agents for the treatment of cancer.
Brough PA; Aherne W; Barril X; Borgognoni J; Boxall K; Cansfield JE; Cheung KM; Collins I; Davies NG; Drysdale MJ; Dymock B; Eccles SA; Finch H; Fink A; Hayes A; Howes R; Hubbard RE; James K; Jordan AM; Lockie A; Martins V; Massey A; Matthews TP; McDonald E; Northfield CJ; Pearl LH; Prodromou C; Ray S; Raynaud FI; Roughley SD; Sharp SY; Surgenor A; Walmsley DL; Webb P; Wood M; Workman P; Wright L
J Med Chem; 2008 Jan; 51(2):196-218. PubMed ID: 18020435
[TBL] [Abstract][Full Text] [Related]
35. Development of a fluorescence polarization assay for the molecular chaperone Hsp90.
Kim J; Felts S; Llauger L; He H; Huezo H; Rosen N; Chiosis G
J Biomol Screen; 2004 Aug; 9(5):375-81. PubMed ID: 15296636
[TBL] [Abstract][Full Text] [Related]
36. Tricyclic series of heat shock protein 90 (Hsp90) inhibitors part I: discovery of tricyclic imidazo[4,5-c]pyridines as potent inhibitors of the Hsp90 molecular chaperone.
Vallée F; Carrez C; Pilorge F; Dupuy A; Parent A; Bertin L; Thompson F; Ferrari P; Fassy F; Lamberton A; Thomas A; Arrebola R; Guerif S; Rohaut A; Certal V; Ruxer JM; Gouyon T; Delorme C; Jouanen A; Dumas J; Grépin C; Combeau C; Goulaouic H; Dereu N; Mikol V; Mailliet P; Minoux H
J Med Chem; 2011 Oct; 54(20):7206-19. PubMed ID: 21972823
[TBL] [Abstract][Full Text] [Related]
37. Identification of potent water soluble purine-scaffold inhibitors of the heat shock protein 90.
He H; Zatorska D; Kim J; Aguirre J; Llauger L; She Y; Wu N; Immormino RM; Gewirth DT; Chiosis G
J Med Chem; 2006 Jan; 49(1):381-90. PubMed ID: 16392823
[TBL] [Abstract][Full Text] [Related]
38. Malachite Green Assay for the Discovery of Heat-Shock Protein 90 Inhibitors.
Gupta SD; Song DG; Lee S; Lee JW; Park JS; Prodromou C; Pan CH
J Vis Exp; 2023 Jan; (191):. PubMed ID: 36744784
[TBL] [Abstract][Full Text] [Related]
39. Lead generation of heat shock protein 90 inhibitors by a combination of fragment-based approach, virtual screening, and structure-based drug design.
Miura T; Fukami TA; Hasegawa K; Ono N; Suda A; Shindo H; Yoon DO; Kim SJ; Na YJ; Aoki Y; Shimma N; Tsukuda T; Shiratori Y
Bioorg Med Chem Lett; 2011 Oct; 21(19):5778-83. PubMed ID: 21875802
[TBL] [Abstract][Full Text] [Related]
40. The Co-chaperone Sba1 connects the ATPase reaction of Hsp90 to the progression of the chaperone cycle.
Richter K; Walter S; Buchner J
J Mol Biol; 2004 Oct; 342(5):1403-13. PubMed ID: 15364569
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
