146 related articles for article (PubMed ID: 15051713)
1. A frameshift mutation and alternate splicing in human brain generate a functional form of the pseudogene cytochrome P4502D7 that demethylates codeine to morphine.
Pai HV; Kommaddi RP; Chinta SJ; Mori T; Boyd MR; Ravindranath V
J Biol Chem; 2004 Jun; 279(26):27383-9. PubMed ID: 15051713
[TBL] [Abstract][Full Text] [Related]
2. Comment on "A frameshift mutation and alternate splicing in human brain generate a functional form of the pseudogene cytochrome P4502d7 that demethylates codeine to morphine", J Biol Chem 279: 27383-27389.
Hoskins JM; Marsh S; McLeod HL
Drug Metab Dispos; 2005 Oct; 33(10):1564-5; author reply 1566. PubMed ID: 16166400
[No Abstract] [Full Text] [Related]
3. Unique cytochromes P450 in human brain: implication in disease pathogenesis.
Ravindranath V; Kommaddi RP; Pai HV
J Neural Transm Suppl; 2006; (70):167-71. PubMed ID: 17017525
[TBL] [Abstract][Full Text] [Related]
4. CYP2D7 splice variants in human liver and brain: does CYP2D7 encode functional protein?
Gaedigk A; Gaedigk R; Leeder JS
Biochem Biophys Res Commun; 2005 Nov; 336(4):1241-50. PubMed ID: 16169517
[TBL] [Abstract][Full Text] [Related]
5. Frequency of the frame-shifting CYP2D7 138delT polymorphism in a large, ethnically diverse sample population.
Bhathena A; Mueller T; Grimm DR; Idler K; Tsurutani A; Spear BB; Katz DA
Drug Metab Dispos; 2007 Aug; 35(8):1251-3. PubMed ID: 17494644
[TBL] [Abstract][Full Text] [Related]
6. Expression and functional analysis of CYP2D6.24, CYP2D6.26, CYP2D6.27, and CYP2D7 isozymes.
Zhang WY; Tu YB; Haining RL; Yu AM
Drug Metab Dispos; 2009 Jan; 37(1):1-4. PubMed ID: 18838503
[TBL] [Abstract][Full Text] [Related]
7. Characterization of the in vitro CYP450 mediated metabolism of the polymorphic CYP2D6 probe drug codeine in horses.
Knych HK; Baden RW; Gretler SR; McKemie DS
Biochem Pharmacol; 2019 Oct; 168():184-192. PubMed ID: 31295464
[TBL] [Abstract][Full Text] [Related]
8. The pharmacogenetics of codeine hypoalgesia.
Sindrup SH; Brøsen K
Pharmacogenetics; 1995 Dec; 5(6):335-46. PubMed ID: 8845855
[TBL] [Abstract][Full Text] [Related]
9. Presence of splice variant forms of cytochrome P4502D1 in rat brain but not in liver.
Chinta SJ; Pai HV; Ravindranath V
Brain Res Mol Brain Res; 2005 Apr; 135(1-2):81-92. PubMed ID: 15857671
[TBL] [Abstract][Full Text] [Related]
10. Microsomal codeine N-demethylation: cosegregation with cytochrome P4503A4 activity.
Caraco Y; Tateishi T; Guengerich FP; Wood AJ
Drug Metab Dispos; 1996 Jul; 24(7):761-4. PubMed ID: 8818573
[TBL] [Abstract][Full Text] [Related]
11. Alternative splicing within the human cytochrome P450 superfamily with an emphasis on the brain: The convolution continues.
Turman CM; Hatley JM; Ryder DJ; Ravindranath V; Strobel HW
Expert Opin Drug Metab Toxicol; 2006 Jun; 2(3):399-418. PubMed ID: 16863442
[TBL] [Abstract][Full Text] [Related]
12. Codeine intoxication associated with ultrarapid CYP2D6 metabolism.
Gasche Y; Daali Y; Fathi M; Chiappe A; Cottini S; Dayer P; Desmeules J
N Engl J Med; 2004 Dec; 351(27):2827-31. PubMed ID: 15625333
[TBL] [Abstract][Full Text] [Related]
13. Polymorphisms in CYP2D6 duplication-negative individuals with the ultrarapid metabolizer phenotype: a role for the CYP2D6*35 allele in ultrarapid metabolism?
Løvlie R; Daly AK; Matre GE; Molven A; Steen VM
Pharmacogenetics; 2001 Feb; 11(1):45-55. PubMed ID: 11207030
[TBL] [Abstract][Full Text] [Related]
14. Functional characterization of CYP2D7 gene variants.
Jukic MM; Lauschke VM; Saito T; Hiratsuka M; Ingelman-Sundberg M
Pharmacogenomics; 2018 Aug; 19(12):931-936. PubMed ID: 30040020
[TBL] [Abstract][Full Text] [Related]
15. Pharmacokinetics of codeine and its metabolite morphine in ultra-rapid metabolizers due to CYP2D6 duplication.
Kirchheiner J; Schmidt H; Tzvetkov M; Keulen JT; Lötsch J; Roots I; Brockmöller J
Pharmacogenomics J; 2007 Aug; 7(4):257-65. PubMed ID: 16819548
[TBL] [Abstract][Full Text] [Related]
16. Investigation of morphine and morphine glucuronide levels and cytochrome P450 isoenzyme 2D6 genotype in codeine-related deaths.
Frost J; Helland A; Nordrum IS; Slørdal L
Forensic Sci Int; 2012 Jul; 220(1-3):6-11. PubMed ID: 22285504
[TBL] [Abstract][Full Text] [Related]
17. Discriminative quantification of cytochrome P4502D6 and 2D7/8 pseudogene expression by TaqMan real-time reverse transcriptase polymerase chain reaction.
Endrizzi K; Fischer J; Klein K; Schwab M; Nüssler A; Neuhaus P; Eichelbaum M; Zanger UM
Anal Biochem; 2002 Jan; 300(2):121-31. PubMed ID: 11779102
[TBL] [Abstract][Full Text] [Related]
18. Endogenous codeine and morphine in poor and extensive metabolisers of the CYP2D6 (debrisoquine/sparteine) polymorphism.
Mikus G; Bochner F; Eichelbaum M; Horak P; Somogyi AA; Spector S
J Pharmacol Exp Ther; 1994 Feb; 268(2):546-51. PubMed ID: 8113966
[TBL] [Abstract][Full Text] [Related]
19. First demonstration that brain CYP2D-mediated opiate metabolic activation alters analgesia in vivo.
Zhou K; Khokhar JY; Zhao B; Tyndale RF
Biochem Pharmacol; 2013 Jun; 85(12):1848-55. PubMed ID: 23623752
[TBL] [Abstract][Full Text] [Related]
20. Pharmacogenomics of codeine, morphine, and morphine-6-glucuronide: model-based analysis of the influence of CYP2D6 activity, UGT2B7 activity, renal impairment, and CYP3A4 inhibition.
Eissing T; Lippert J; Willmann S
Mol Diagn Ther; 2012 Feb; 16(1):43-53. PubMed ID: 22352453
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
