142 related articles for article (PubMed ID: 15055989)
1. Aza-peptide Michael acceptors: a new class of inhibitors specific for caspases and other clan CD cysteine proteases.
Ekici OD; Götz MG; James KE; Li ZZ; Rukamp BJ; Asgian JL; Caffrey CR; Hansell E; Dvorák J; McKerrow JH; Potempa J; Travis J; Mikolajczyk J; Salvesen GS; Powers JC
J Med Chem; 2004 Apr; 47(8):1889-92. PubMed ID: 15055989
[TBL] [Abstract][Full Text] [Related]
2. Aza-peptide epoxides: a new class of inhibitors selective for clan CD cysteine proteases.
Asgian JL; James KE; Li ZZ; Carter W; Barrett AJ; Mikolajczyk J; Salvesen GS; Powers JC
J Med Chem; 2002 Nov; 45(23):4958-60. PubMed ID: 12408706
[TBL] [Abstract][Full Text] [Related]
3. Design, synthesis, and evaluation of aza-peptide Michael acceptors as selective and potent inhibitors of caspases-2, -3, -6, -7, -8, -9, and -10.
Ekici OD; Li ZZ; Campbell AJ; James KE; Asgian JL; Mikolajczyk J; Salvesen GS; Ganesan R; Jelakovic S; Grütter MG; Powers JC
J Med Chem; 2006 Sep; 49(19):5728-49. PubMed ID: 16970398
[TBL] [Abstract][Full Text] [Related]
4. Aza-peptide epoxides: potent and selective inhibitors of Schistosoma mansoni and pig kidney legumains (asparaginyl endopeptidases).
James KE; Götz MG; Caffrey CR; Hansell E; Carter W; Barrett AJ; McKerrow JH; Powers JC
Biol Chem; 2003 Dec; 384(12):1613-8. PubMed ID: 14719804
[TBL] [Abstract][Full Text] [Related]
5. Design, synthesis, and evaluation of aza-peptide epoxides as selective and potent inhibitors of caspases-1, -3, -6, and -8.
James KE; Asgian JL; Li ZZ; Ekici OD; Rubin JR; Mikolajczyk J; Salvesen GS; Powers JC
J Med Chem; 2004 Mar; 47(6):1553-74. PubMed ID: 14998341
[TBL] [Abstract][Full Text] [Related]
6. Novel aza peptide inhibitors and active-site probes of papain-family cysteine proteases.
Verhelst SH; Witte MD; Arastu-Kapur S; Fonovic M; Bogyo M
Chembiochem; 2006 Jun; 7(6):943-50. PubMed ID: 16607671
[TBL] [Abstract][Full Text] [Related]
7. Specificity of aza-peptide electrophile activity-based probes of caspases.
Sexton KB; Kato D; Berger AB; Fonovic M; Verhelst SH; Bogyo M
Cell Death Differ; 2007 Apr; 14(4):727-32. PubMed ID: 17170749
[TBL] [Abstract][Full Text] [Related]
8. Aza-peptidyl Michael acceptors. A new class of potent and selective inhibitors of asparaginyl endopeptidases (legumains) from evolutionarily diverse pathogens.
Götz MG; James KE; Hansell E; Dvorák J; Seshaadri A; Sojka D; Kopácek P; McKerrow JH; Caffrey CR; Powers JC
J Med Chem; 2008 May; 51(9):2816-32. PubMed ID: 18416543
[TBL] [Abstract][Full Text] [Related]
9. Inhibition of distant caspase homologues by natural caspase inhibitors.
Snipas SJ; Stennicke HR; Riedl S; Potempa J; Travis J; Barrett AJ; Salvesen GS
Biochem J; 2001 Jul; 357(Pt 2):575-80. PubMed ID: 11439111
[TBL] [Abstract][Full Text] [Related]
10. Design, synthesis, and
Corrigan TS; Lotti Diaz LM; Border SE; Ratigan SC; Kasper KQ; Sojka D; Fajtova P; Caffrey CR; Salvesen GS; McElroy CA; Hadad CM; Doğan Ekici Ö
J Enzyme Inhib Med Chem; 2020 Dec; 35(1):1387-1402. PubMed ID: 32633155
[TBL] [Abstract][Full Text] [Related]
11. Azadipeptide nitriles: highly potent and proteolytically stable inhibitors of papain-like cysteine proteases.
Löser R; Frizler M; Schilling K; Gütschow M
Angew Chem Int Ed Engl; 2008; 47(23):4331-4. PubMed ID: 18404765
[No Abstract] [Full Text] [Related]
12. A general solid phase method for the preparation of diverse azapeptide probes directed against cysteine proteases.
Kato D; Verhelst SH; Sexton KB; Bogyo M
Org Lett; 2005 Dec; 7(25):5649-52. PubMed ID: 16321013
[TBL] [Abstract][Full Text] [Related]
13. New peptidic cysteine protease inhibitors derived from the electrophilic alpha-amino acid aziridine-2,3-dicarboxylic acid.
Schirmeister T
J Med Chem; 1999 Feb; 42(4):560-72. PubMed ID: 10052963
[TBL] [Abstract][Full Text] [Related]
14. Exploring the S4 and S1 prime subsite specificities in caspase-3 with aza-peptide epoxide inhibitors.
Ganesan R; Jelakovic S; Campbell AJ; Li ZZ; Asgian JL; Powers JC; Grütter MG
Biochemistry; 2006 Aug; 45(30):9059-67. PubMed ID: 16866351
[TBL] [Abstract][Full Text] [Related]
15. Cysteine protease inhibition by azapeptide esters.
Magrath J; Abeles RH
J Med Chem; 1992 Nov; 35(23):4279-83. PubMed ID: 1447732
[TBL] [Abstract][Full Text] [Related]
16. Design, synthesis, and evaluation of azapeptides as substrates and inhibitors for human rhinovirus 3C protease.
Venkatraman S; Kong J; Nimkar S; Wang QM; Aubé J; Hanzlik RP
Bioorg Med Chem Lett; 1999 Feb; 9(4):577-80. PubMed ID: 10098667
[TBL] [Abstract][Full Text] [Related]
17. Identification of the active site of legumain links it to caspases, clostripain and gingipains in a new clan of cysteine endopeptidases.
Chen JM; Rawlings ND; Stevens RA; Barrett AJ
FEBS Lett; 1998 Dec; 441(3):361-5. PubMed ID: 9891971
[TBL] [Abstract][Full Text] [Related]
18. Azapeptides structurally based upon inhibitory sites of cystatins as potent and selective inhibitors of cysteine proteases.
Wieczerzak E; Drabik P; Łankiewicz L; Ołdziej S; Grzonka Z; Abrahamson M; Grubb A; Brömme D
J Med Chem; 2002 Sep; 45(19):4202-11. PubMed ID: 12213061
[TBL] [Abstract][Full Text] [Related]
19. Inhibition of mammalian legumain by Michael acceptors and AzaAsn-halomethylketones.
Niestroj AJ; Feussner K; Heiser U; Dando PM; Barrett A; Gerhartz B; Demuth HU
Biol Chem; 2002; 383(7-8):1205-14. PubMed ID: 12437107
[TBL] [Abstract][Full Text] [Related]
20. Peptidyl beta-homo-aspartals (3-amino-4-carboxybutyraldehydes): new specific inhibitors of caspases.
Bajusz S; Fauszt I; Németh K; Barabás E; Juhász A; Patthy M; Bauer PI
Biopolymers; 1999; 51(1):109-18. PubMed ID: 10380358
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
