These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
208 related articles for article (PubMed ID: 15057143)
1. 17-(Allylamino)-17-demethoxygeldanamycin activity in human melanoma models. Burger AM; Fiebig HH; Stinson SF; Sausville EA Anticancer Drugs; 2004 Apr; 15(4):377-87. PubMed ID: 15057143 [TBL] [Abstract][Full Text] [Related]
2. Comparison of 17-dimethylaminoethylamino-17-demethoxy-geldanamycin (17DMAG) and 17-allylamino-17-demethoxygeldanamycin (17AAG) in vitro: effects on Hsp90 and client proteins in melanoma models. Smith V; Sausville EA; Camalier RF; Fiebig HH; Burger AM Cancer Chemother Pharmacol; 2005 Aug; 56(2):126-37. PubMed ID: 15841378 [TBL] [Abstract][Full Text] [Related]
3. Pharmacokinetic-pharmacodynamic relationships for the heat shock protein 90 molecular chaperone inhibitor 17-allylamino, 17-demethoxygeldanamycin in human ovarian cancer xenograft models. Banerji U; Walton M; Raynaud F; Grimshaw R; Kelland L; Valenti M; Judson I; Workman P Clin Cancer Res; 2005 Oct; 11(19 Pt 1):7023-32. PubMed ID: 16203796 [TBL] [Abstract][Full Text] [Related]
4. 17-Allylamino-17-demethoxygeldanamycin induces the degradation of androgen receptor and HER-2/neu and inhibits the growth of prostate cancer xenografts. Solit DB; Zheng FF; Drobnjak M; Münster PN; Higgins B; Verbel D; Heller G; Tong W; Cordon-Cardo C; Agus DB; Scher HI; Rosen N Clin Cancer Res; 2002 May; 8(5):986-93. PubMed ID: 12006510 [TBL] [Abstract][Full Text] [Related]
5. FLT3 expressing leukemias are selectively sensitive to inhibitors of the molecular chaperone heat shock protein 90 through destabilization of signal transduction-associated kinases. Yao Q; Nishiuchi R; Li Q; Kumar AR; Hudson WA; Kersey JH Clin Cancer Res; 2003 Oct; 9(12):4483-93. PubMed ID: 14555522 [TBL] [Abstract][Full Text] [Related]
6. 17-AAG inhibits vemurafenib-associated MAP kinase activation and is synergistic with cellular immunotherapy in a murine melanoma model. Joshi SS; Jiang S; Unni E; Goding SR; Fan T; Antony PA; Hornyak TJ PLoS One; 2018; 13(2):e0191264. PubMed ID: 29481571 [TBL] [Abstract][Full Text] [Related]
7. Activated B-RAF is an Hsp90 client protein that is targeted by the anticancer drug 17-allylamino-17-demethoxygeldanamycin. da Rocha Dias S; Friedlos F; Light Y; Springer C; Workman P; Marais R Cancer Res; 2005 Dec; 65(23):10686-91. PubMed ID: 16322212 [TBL] [Abstract][Full Text] [Related]
8. Geldanamycin and 17-allylamino-17-demethoxygeldanamycin potentiate the in vitro and in vivo radiation response of cervical tumor cells via the heat shock protein 90-mediated intracellular signaling and cytotoxicity. Bisht KS; Bradbury CM; Mattson D; Kaushal A; Sowers A; Markovina S; Ortiz KL; Sieck LK; Isaacs JS; Brechbiel MW; Mitchell JB; Neckers LM; Gius D Cancer Res; 2003 Dec; 63(24):8984-95. PubMed ID: 14695217 [TBL] [Abstract][Full Text] [Related]
9. Modulation of Hsp90 function by ansamycins sensitizes breast cancer cells to chemotherapy-induced apoptosis in an RB- and schedule-dependent manner. See: E. A. Sausville, Combining cytotoxics and 17-allylamino, 17-demethoxygeldanamycin: sequence and tumor biology matters, Clin. Cancer Res., 7: 2155-2158, 2001. Münster PN; Basso A; Solit D; Norton L; Rosen N Clin Cancer Res; 2001 Aug; 7(8):2228-36. PubMed ID: 11489796 [TBL] [Abstract][Full Text] [Related]
10. Inhibition of heat shock protein 90 function down-regulates Akt kinase and sensitizes tumors to Taxol. Solit DB; Basso AD; Olshen AB; Scher HI; Rosen N Cancer Res; 2003 May; 63(9):2139-44. PubMed ID: 12727831 [TBL] [Abstract][Full Text] [Related]
11. The Hsp90 chaperone complex as a novel target for cancer therapy. Goetz MP; Toft DO; Ames MM; Erlichman C Ann Oncol; 2003 Aug; 14(8):1169-76. PubMed ID: 12881371 [TBL] [Abstract][Full Text] [Related]
12. Dimeric ansamycins--a new class of antitumor Hsp90 modulators with prolonged inhibitory activity. Zhang H; Yang YC; Zhang L; Fan J; Chung D; Choi D; Grecko R; Timony G; Karjian P; Boehm M; Burrows F Int J Cancer; 2007 Feb; 120(4):918-26. PubMed ID: 17131314 [TBL] [Abstract][Full Text] [Related]
13. Inhibition of telomerase activity by geldanamycin and 17-allylamino, 17-demethoxygeldanamycin in human melanoma cells. Villa R; Folini M; Porta CD; Valentini A; Pennati M; Daidone MG; Zaffaroni N Carcinogenesis; 2003 May; 24(5):851-9. PubMed ID: 12771028 [TBL] [Abstract][Full Text] [Related]
14. Formation of 17-allylamino-demethoxygeldanamycin (17-AAG) hydroquinone by NAD(P)H:quinone oxidoreductase 1: role of 17-AAG hydroquinone in heat shock protein 90 inhibition. Guo W; Reigan P; Siegel D; Zirrolli J; Gustafson D; Ross D Cancer Res; 2005 Nov; 65(21):10006-15. PubMed ID: 16267026 [TBL] [Abstract][Full Text] [Related]
15. The heat shock protein 90 inhibitor, 17-allylamino-17-demethoxygeldanamycin, enhances osteoclast formation and potentiates bone metastasis of a human breast cancer cell line. Price JT; Quinn JM; Sims NA; Vieusseux J; Waldeck K; Docherty SE; Myers D; Nakamura A; Waltham MC; Gillespie MT; Thompson EW Cancer Res; 2005 Jun; 65(11):4929-38. PubMed ID: 15930315 [TBL] [Abstract][Full Text] [Related]
16. An in vitro and in vivo study of the combination of the heat shock protein inhibitor 17-allylamino-17-demethoxygeldanamycin and carboplatin in human ovarian cancer models. Banerji U; Sain N; Sharp SY; Valenti M; Asad Y; Ruddle R; Raynaud F; Walton M; Eccles SA; Judson I; Jackman AL; Workman P Cancer Chemother Pharmacol; 2008 Oct; 62(5):769-78. PubMed ID: 18193424 [TBL] [Abstract][Full Text] [Related]
17. Identification of new biomarkers for clinical trials of Hsp90 inhibitors. Zhang H; Chung D; Yang YC; Neely L; Tsurumoto S; Fan J; Zhang L; Biamonte M; Brekken J; Lundgren K; Burrows F Mol Cancer Ther; 2006 May; 5(5):1256-64. PubMed ID: 16731758 [TBL] [Abstract][Full Text] [Related]
18. 17-AAG and 17-DMAG-induced inhibition of cell proliferation through B-Raf downregulation in WT B-Raf-expressing uveal melanoma cell lines. Babchia N; Calipel A; Mouriaux F; Faussat AM; Mascarelli F Invest Ophthalmol Vis Sci; 2008 Jun; 49(6):2348-56. PubMed ID: 18281615 [TBL] [Abstract][Full Text] [Related]
19. The HSP90 inhibitor 17-AAG exhibits potent antitumor activity for pheochromocytoma in a xenograft model. Xu Y; Zhu Q; Chen D; Shen Z; Wang W; Ning G; Zhu Y Tumour Biol; 2015 Jul; 36(7):5103-8. PubMed ID: 25682284 [TBL] [Abstract][Full Text] [Related]
20. Inhibition of 90-kD heat shock protein potentiates the cytotoxicity of chemotherapeutic agents in human glioma cells. Ohba S; Hirose Y; Yoshida K; Yazaki T; Kawase T J Neurosurg; 2010 Jan; 112(1):33-42. PubMed ID: 19408974 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]