These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

287 related articles for article (PubMed ID: 15060152)

  • 1. Mutations linked to leukoencephalopathy with vanishing white matter impair the function of the eukaryotic initiation factor 2B complex in diverse ways.
    Li W; Wang X; Van Der Knaap MS; Proud CG
    Mol Cell Biol; 2004 Apr; 24(8):3295-306. PubMed ID: 15060152
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A yeast purification system for human translation initiation factors eIF2 and eIF2Bε and their use in the diagnosis of CACH/VWM disease.
    de Almeida RA; Fogli A; Gaillard M; Scheper GC; Boesflug-Tanguy O; Pavitt GD
    PLoS One; 2013; 8(1):e53958. PubMed ID: 23335982
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Identification of domains and residues within the epsilon subunit of eukaryotic translation initiation factor 2B (eIF2Bepsilon) required for guanine nucleotide exchange reveals a novel activation function promoted by eIF2B complex formation.
    Gomez E; Pavitt GD
    Mol Cell Biol; 2000 Jun; 20(11):3965-76. PubMed ID: 10805739
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Mutations in each of the five subunits of translation initiation factor eIF2B can cause leukoencephalopathy with vanishing white matter.
    van der Knaap MS; Leegwater PA; Könst AA; Visser A; Naidu S; Oudejans CB; Schutgens RB; Pronk JC
    Ann Neurol; 2002 Feb; 51(2):264-70. PubMed ID: 11835386
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Mutations causing childhood ataxia with central nervous system hypomyelination reduce eukaryotic initiation factor 2B complex formation and activity.
    Richardson JP; Mohammad SS; Pavitt GD
    Mol Cell Biol; 2004 Mar; 24(6):2352-63. PubMed ID: 14993275
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The large spectrum of eIF2B-related diseases.
    Fogli A; Boespflug-Tanguy O
    Biochem Soc Trans; 2006 Feb; 34(Pt 1):22-9. PubMed ID: 16246171
    [TBL] [Abstract][Full Text] [Related]  

  • 7. eIF2B: recent structural and functional insights into a key regulator of translation.
    Wortham NC; Proud CG
    Biochem Soc Trans; 2015 Dec; 43(6):1234-40. PubMed ID: 26614666
    [TBL] [Abstract][Full Text] [Related]  

  • 8. [Eukaryotic translation initiation factor 2B and leukoencephalopathy with vanishing white matter].
    Pan YX; Wu Y; Niu ZP; Jiang YW
    Beijing Da Xue Xue Bao Yi Xue Ban; 2009 Oct; 41(5):608-10. PubMed ID: 19829687
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Biochemical effects of mutations in the gene encoding the alpha subunit of eukaryotic initiation factor (eIF) 2B associated with Vanishing White Matter disease.
    Wortham NC; Proud CG
    BMC Med Genet; 2015 Aug; 16():64. PubMed ID: 26285592
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Subunits of the translation initiation factor eIF2B are mutant in leukoencephalopathy with vanishing white matter.
    Leegwater PA; Vermeulen G; Könst AA; Naidu S; Mulders J; Visser A; Kersbergen P; Mobach D; Fonds D; van Berkel CG; Lemmers RJ; Frants RR; Oudejans CB; Schutgens RB; Pronk JC; van der Knaap MS
    Nat Genet; 2001 Dec; 29(4):383-8. PubMed ID: 11704758
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Severity of vanishing white matter disease does not correlate with deficits in eIF2B activity or the integrity of eIF2B complexes.
    Liu R; van der Lei HD; Wang X; Wortham NC; Tang H; van Berkel CG; Mufunde TA; Huang W; van der Knaap MS; Scheper GC; Proud CG
    Hum Mutat; 2011 Sep; 32(9):1036-45. PubMed ID: 21560189
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Vanishing white matter: deregulated integrated stress response as therapy target.
    Abbink TEM; Wisse LE; Jaku E; Thiecke MJ; Voltolini-González D; Fritsen H; Bobeldijk S; Ter Braak TJ; Polder E; Postma NL; Bugiani M; Struijs EA; Verheijen M; Straat N; van der Sluis S; Thomas AAM; Molenaar D; van der Knaap MS
    Ann Clin Transl Neurol; 2019 Aug; 6(8):1407-1422. PubMed ID: 31402619
    [TBL] [Abstract][Full Text] [Related]  

  • 13. eIF2B, a mediator of general and gene-specific translational control.
    Pavitt GD
    Biochem Soc Trans; 2005 Dec; 33(Pt 6):1487-92. PubMed ID: 16246152
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Stoichiometry of the eIF2B complex is maintained by mutual stabilization of subunits.
    Wortham NC; Stewart JD; Harris S; Coldwell MJ; Proud CG
    Biochem J; 2016 Mar; 473(5):571-80. PubMed ID: 26614765
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Paradoxical Sensitivity to an Integrated Stress Response Blocking Mutation in Vanishing White Matter Cells.
    Sekine Y; Zyryanova A; Crespillo-Casado A; Amin-Wetzel N; Harding HP; Ron D
    PLoS One; 2016; 11(11):e0166278. PubMed ID: 27812215
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The beta/Gcd7 subunit of eukaryotic translation initiation factor 2B (eIF2B), a guanine nucleotide exchange factor, is crucial for binding eIF2 in vivo.
    Dev K; Qiu H; Dong J; Zhang F; Barthlme D; Hinnebusch AG
    Mol Cell Biol; 2010 Nov; 30(21):5218-33. PubMed ID: 20805354
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Poor cerebral inflammatory response in eIF2B knock-in mice: implications for the aetiology of vanishing white matter disease.
    Cabilly Y; Barbi M; Geva M; Marom L; Chetrit D; Ehrlich M; Elroy-Stein O
    PLoS One; 2012; 7(10):e46715. PubMed ID: 23056417
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Analysis of the subunit organization of the eIF2B complex reveals new insights into its structure and regulation.
    Wortham NC; Martinez M; Gordiyenko Y; Robinson CV; Proud CG
    FASEB J; 2014 May; 28(5):2225-37. PubMed ID: 24532666
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Expression, purification, and crystallization of Schizosaccharomyces pombe eIF2B.
    Kashiwagi K; Shigeta T; Imataka H; Ito T; Yokoyama S
    J Struct Funct Genomics; 2016 Mar; 17(1):33-8. PubMed ID: 27023709
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Vanishing white matter: Eukaryotic initiation factor 2B model and the impact of missense mutations.
    Slynko I; Nguyen S; Hamilton EMC; Wisse LE; de Esch IJP; de Graaf C; Bruning JB; Proud CG; Abbink TEM; van der Knaap MS
    Mol Genet Genomic Med; 2021 Mar; 9(3):e1593. PubMed ID: 33432707
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.