689 related articles for article (PubMed ID: 15064394)
1. Ubiquitylation of synphilin-1 and alpha-synuclein by SIAH and its presence in cellular inclusions and Lewy bodies imply a role in Parkinson's disease.
Liani E; Eyal A; Avraham E; Shemer R; Szargel R; Berg D; Bornemann A; Riess O; Ross CA; Rott R; Engelender S
Proc Natl Acad Sci U S A; 2004 Apr; 101(15):5500-5. PubMed ID: 15064394
[TBL] [Abstract][Full Text] [Related]
2. Synphilin-1A inhibits seven in absentia homolog (SIAH) and modulates alpha-synuclein monoubiquitylation and inclusion formation.
Szargel R; Rott R; Eyal A; Haskin J; Shani V; Balan L; Wolosker H; Engelender S
J Biol Chem; 2009 Apr; 284(17):11706-16. PubMed ID: 19224863
[TBL] [Abstract][Full Text] [Related]
3. Parkin ubiquitinates the alpha-synuclein-interacting protein, synphilin-1: implications for Lewy-body formation in Parkinson disease.
Chung KK; Zhang Y; Lim KL; Tanaka Y; Huang H; Gao J; Ross CA; Dawson VL; Dawson TM
Nat Med; 2001 Oct; 7(10):1144-50. PubMed ID: 11590439
[TBL] [Abstract][Full Text] [Related]
4. Glycogen synthase kinase 3beta modulates synphilin-1 ubiquitylation and cellular inclusion formation by SIAH: implications for proteasomal function and Lewy body formation.
Avraham E; Szargel R; Eyal A; Rott R; Engelender S
J Biol Chem; 2005 Dec; 280(52):42877-86. PubMed ID: 16174773
[TBL] [Abstract][Full Text] [Related]
5. Parkin mediates nonclassical, proteasomal-independent ubiquitination of synphilin-1: implications for Lewy body formation.
Lim KL; Chew KC; Tan JM; Wang C; Chung KK; Zhang Y; Tanaka Y; Smith W; Engelender S; Ross CA; Dawson VL; Dawson TM
J Neurosci; 2005 Feb; 25(8):2002-9. PubMed ID: 15728840
[TBL] [Abstract][Full Text] [Related]
6. Siah-1 facilitates ubiquitination and degradation of synphilin-1.
Nagano Y; Yamashita H; Takahashi T; Kishida S; Nakamura T; Iseki E; Hattori N; Mizuno Y; Kikuchi A; Matsumoto M
J Biol Chem; 2003 Dec; 278(51):51504-14. PubMed ID: 14506261
[TBL] [Abstract][Full Text] [Related]
7. Dorfin localizes to Lewy bodies and ubiquitylates synphilin-1.
Ito T; Niwa J; Hishikawa N; Ishigaki S; Doyu M; Sobue G
J Biol Chem; 2003 Aug; 278(31):29106-14. PubMed ID: 12750386
[TBL] [Abstract][Full Text] [Related]
8. Synphilin isoforms and the search for a cellular model of lewy body formation in Parkinson's disease.
Eyal A; Engelender S
Cell Cycle; 2006 Sep; 5(18):2082-6. PubMed ID: 16969096
[TBL] [Abstract][Full Text] [Related]
9. Synphilin-1 isoforms in Parkinson's disease: regulation by phosphorylation and ubiquitylation.
Szargel R; Rott R; Engelender S
Cell Mol Life Sci; 2008 Jan; 65(1):80-8. PubMed ID: 17982729
[TBL] [Abstract][Full Text] [Related]
10. Synphilin-1 associates with alpha-synuclein and promotes the formation of cytosolic inclusions.
Engelender S; Kaminsky Z; Guo X; Sharp AH; Amaravi RK; Kleiderlein JJ; Margolis RL; Troncoso JC; Lanahan AA; Worley PF; Dawson VL; Dawson TM; Ross CA
Nat Genet; 1999 May; 22(1):110-4. PubMed ID: 10319874
[TBL] [Abstract][Full Text] [Related]
11. Ubiquitination of alpha-synuclein by Siah-1 promotes alpha-synuclein aggregation and apoptotic cell death.
Lee JT; Wheeler TC; Li L; Chin LS
Hum Mol Genet; 2008 Mar; 17(6):906-17. PubMed ID: 18065497
[TBL] [Abstract][Full Text] [Related]
12. UCH-L1 aggresome formation in response to proteasome impairment indicates a role in inclusion formation in Parkinson's disease.
Ardley HC; Scott GB; Rose SA; Tan NG; Robinson PA
J Neurochem; 2004 Jul; 90(2):379-91. PubMed ID: 15228595
[TBL] [Abstract][Full Text] [Related]
13. Ubiquitination of alpha-synuclein and autophagy in Parkinson's disease.
Engelender S
Autophagy; 2008 Apr; 4(3):372-4. PubMed ID: 18216494
[TBL] [Abstract][Full Text] [Related]
14. Monoubiquitylation of alpha-synuclein by seven in absentia homolog (SIAH) promotes its aggregation in dopaminergic cells.
Rott R; Szargel R; Haskin J; Shani V; Shainskaya A; Manov I; Liani E; Avraham E; Engelender S
J Biol Chem; 2008 Feb; 283(6):3316-3328. PubMed ID: 18070888
[TBL] [Abstract][Full Text] [Related]
15. Alpha-synuclein-enhanced green fluorescent protein fusion proteins form proteasome sensitive inclusions in primary neurons.
McLean PJ; Kawamata H; Hyman BT
Neuroscience; 2001; 104(3):901-12. PubMed ID: 11440819
[TBL] [Abstract][Full Text] [Related]
16. Synphilin-1 degradation by the ubiquitin-proteasome pathway and effects on cell survival.
Lee G; Junn E; Tanaka M; Kim YM; Mouradian MM
J Neurochem; 2002 Oct; 83(2):346-52. PubMed ID: 12423244
[TBL] [Abstract][Full Text] [Related]
17. alpha-Synuclein is colocalized with 14-3-3 and synphilin-1 in A53T transgenic mice.
Shirakashi Y; Kawamoto Y; Tomimoto H; Takahashi R; Ihara M
Acta Neuropathol; 2006 Dec; 112(6):681-9. PubMed ID: 16957925
[TBL] [Abstract][Full Text] [Related]
18. Aggresomes formed by alpha-synuclein and synphilin-1 are cytoprotective.
Tanaka M; Kim YM; Lee G; Junn E; Iwatsubo T; Mouradian MM
J Biol Chem; 2004 Feb; 279(6):4625-31. PubMed ID: 14627698
[TBL] [Abstract][Full Text] [Related]
19. Ubiquitin-proteasome system and Parkinson's diseases.
Betarbet R; Sherer TB; Greenamyre JT
Exp Neurol; 2005 Feb; 191 Suppl 1():S17-27. PubMed ID: 15629758
[TBL] [Abstract][Full Text] [Related]
20. Parkinson's disease transgenic mitochondrial cybrids generate Lewy inclusion bodies.
Trimmer PA; Borland MK; Keeney PM; Bennett JP; Parker WD
J Neurochem; 2004 Feb; 88(4):800-12. PubMed ID: 14756800
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]