BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

169 related articles for article (PubMed ID: 15064712)

  • 1. Degradation of PKB/Akt protein by inhibition of the VEGF receptor/mTOR pathway in endothelial cells.
    Riesterer O; Zingg D; Hummerjohann J; Bodis S; Pruschy M
    Oncogene; 2004 Jun; 23(26):4624-35. PubMed ID: 15064712
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Differential activation of the phosphatidylinositol 3'-kinase/Akt survival pathway by ionizing radiation in tumor and primary endothelial cells.
    Zingg D; Riesterer O; Fabbro D; Glanzmann C; Bodis S; Pruschy M
    Cancer Res; 2004 Aug; 64(15):5398-406. PubMed ID: 15289348
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Phosphatidylinositol 3-kinase (PI-3K)/Akt but not PI-3K/p70 S6 kinase signaling mediates IGF-1-promoted lens epithelial cell survival.
    Chandrasekher G; Sailaja D
    Invest Ophthalmol Vis Sci; 2004 Oct; 45(10):3577-88. PubMed ID: 15452065
    [TBL] [Abstract][Full Text] [Related]  

  • 4. mTOR inhibitor RAD001 (everolimus) has antiangiogenic/vascular properties distinct from a VEGFR tyrosine kinase inhibitor.
    Lane HA; Wood JM; McSheehy PM; Allegrini PR; Boulay A; Brueggen J; Littlewood-Evans A; Maira SM; Martiny-Baron G; Schnell CR; Sini P; O'Reilly T
    Clin Cancer Res; 2009 Mar; 15(5):1612-22. PubMed ID: 19223496
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Chimeric VEGFRs are activated by a small-molecule dimerizer and mediate downstream signalling cascades in endothelial cells.
    Knight EL; Warner AJ; Maxwell A; Prigent SA
    Oncogene; 2000 Nov; 19(47):5398-405. PubMed ID: 11103941
    [TBL] [Abstract][Full Text] [Related]  

  • 6. EGF receptor transactivation mediates ANG II-stimulated mitogenesis in intestinal epithelial cells through the PI3-kinase/Akt/mTOR/p70S6K1 signaling pathway.
    Chiu T; Santiskulvong C; Rozengurt E
    Am J Physiol Gastrointest Liver Physiol; 2005 Feb; 288(2):G182-94. PubMed ID: 15358595
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Preferential dependence of breast cancer cells versus normal cells on integrin-linked kinase for protein kinase B/Akt activation and cell survival.
    Troussard AA; McDonald PC; Wederell ED; Mawji NM; Filipenko NR; Gelmon KA; Kucab JE; Dunn SE; Emerman JT; Bally MB; Dedhar S
    Cancer Res; 2006 Jan; 66(1):393-403. PubMed ID: 16397254
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Tissue factor pathway inhibitor-2 is upregulated by vascular endothelial growth factor and suppresses growth factor-induced proliferation of endothelial cells.
    Xu Z; Maiti D; Kisiel W; Duh EJ
    Arterioscler Thromb Vasc Biol; 2006 Dec; 26(12):2819-25. PubMed ID: 17023682
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Survival signaling by Notch1: mammalian target of rapamycin (mTOR)-dependent inhibition of p53.
    Mungamuri SK; Yang X; Thor AD; Somasundaram K
    Cancer Res; 2006 May; 66(9):4715-24. PubMed ID: 16651424
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Diosgenin induces hypoxia-inducible factor-1 activation and angiogenesis through estrogen receptor-related phosphatidylinositol 3-kinase/Akt and p38 mitogen-activated protein kinase pathways in osteoblasts.
    Yen ML; Su JL; Chien CL; Tseng KW; Yang CY; Chen WF; Chang CC; Kuo ML
    Mol Pharmacol; 2005 Oct; 68(4):1061-73. PubMed ID: 15998873
    [TBL] [Abstract][Full Text] [Related]  

  • 11. AKT activity regulates the ability of mTOR inhibitors to prevent angiogenesis and VEGF expression in multiple myeloma cells.
    Frost P; Shi Y; Hoang B; Lichtenstein A
    Oncogene; 2007 Apr; 26(16):2255-62. PubMed ID: 17016437
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Regulation of vascular endothelial growth factor expression by EMMPRIN via the PI3K-Akt signaling pathway.
    Tang Y; Nakada MT; Rafferty P; Laraio J; McCabe FL; Millar H; Cunningham M; Snyder LA; Bugelski P; Yan L
    Mol Cancer Res; 2006 Jun; 4(6):371-7. PubMed ID: 16778084
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Intracellular signaling in tumor and endothelial cells: The expected and, yet again, the unexpected.
    Stoeltzing O; Meric-Bernstam F; Ellis LM
    Cancer Cell; 2006 Aug; 10(2):89-91. PubMed ID: 16904605
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Bcl-2 phosphorylation and apoptosis activated by damaged microtubules require mTOR and are regulated by Akt.
    Asnaghi L; Calastretti A; Bevilacqua A; D'Agnano I; Gatti G; Canti G; Delia D; Capaccioli S; Nicolin A
    Oncogene; 2004 Jul; 23(34):5781-91. PubMed ID: 15208671
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The histone deacetylase inhibitor NVP-LAQ824 inhibits angiogenesis and has a greater antitumor effect in combination with the vascular endothelial growth factor receptor tyrosine kinase inhibitor PTK787/ZK222584.
    Qian DZ; Wang X; Kachhap SK; Kato Y; Wei Y; Zhang L; Atadja P; Pili R
    Cancer Res; 2004 Sep; 64(18):6626-34. PubMed ID: 15374977
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Gonadotropin-releasing hormone induces apoptosis of prostate cancer cells: role of c-Jun NH2-terminal kinase, protein kinase B, and extracellular signal-regulated kinase pathways.
    Kraus S; Levy G; Hanoch T; Naor Z; Seger R
    Cancer Res; 2004 Aug; 64(16):5736-44. PubMed ID: 15313914
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Distinctive role of integrin-mediated adhesion in TNF-induced PKB/Akt and NF-kappaB activation and endothelial cell survival.
    Bieler G; Hasmim M; Monnier Y; Imaizumi N; Ameyar M; Bamat J; Ponsonnet L; Chouaib S; Grell M; Goodman SL; Lejeune F; Rüegg C
    Oncogene; 2007 Aug; 26(39):5722-32. PubMed ID: 17369858
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Versatile inducible activation system of Akt/PKB signaling pathway in mice.
    Kroll J; Cobo P; Sato TN
    Genesis; 2003 Mar; 35(3):160-3. PubMed ID: 12640620
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Akt/PKB regulates laminin and collagen IV isotypes of the basement membrane.
    Li X; Talts U; Talts JF; Arman E; Ekblom P; Lonai P
    Proc Natl Acad Sci U S A; 2001 Dec; 98(25):14416-21. PubMed ID: 11734644
    [TBL] [Abstract][Full Text] [Related]  

  • 20. TNF-alpha stimulation of MCP-1 expression is mediated by the Akt/PKB signal transduction pathway in vascular endothelial cells.
    Murao K; Ohyama T; Imachi H; Ishida T; Cao WM; Namihira H; Sato M; Wong NC; Takahara J
    Biochem Biophys Res Commun; 2000 Sep; 276(2):791-6. PubMed ID: 11027549
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.