BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

224 related articles for article (PubMed ID: 15066178)

  • 1. Cell surface adhesion of pregnancy-associated plasma protein-A is mediated by four clusters of basic residues located in its third and fourth CCP module.
    Weyer K; Overgaard MT; Laursen LS; Nielsen CG; Schmitz A; Christiansen M; Sottrup-Jensen L; Giudice LC; Oxvig C
    Eur J Biochem; 2004 Apr; 271(8):1525-35. PubMed ID: 15066178
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Cell surface targeting of pregnancy-associated plasma protein A proteolytic activity. Reversible adhesion is mediated by two neighboring short consensus repeats.
    Laursen LS; Overgaard MT; Weyer K; Boldt HB; Ebbesen P; Christiansen M; Sottrup-Jensen L; Giudice LC; Oxvig C
    J Biol Chem; 2002 Dec; 277(49):47225-34. PubMed ID: 12370176
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Substrate specificity of the metalloproteinase pregnancy-associated plasma protein-A (PAPP-A) assessed by mutagenesis and analysis of synthetic peptides: substrate residues distant from the scissile bond are critical for proteolysis.
    Laursen LS; Overgaard MT; Nielsen CG; Boldt HB; Hopmann KH; Conover CA; Sottrup-Jensen L; Giudice LC; Oxvig C
    Biochem J; 2002 Oct; 367(Pt 1):31-40. PubMed ID: 12241545
    [TBL] [Abstract][Full Text] [Related]  

  • 4. A substrate specificity-determining unit of three Lin12-Notch repeat modules is formed in trans within the pappalysin-1 dimer and requires a sequence stretch C-terminal to the third module.
    Weyer K; Boldt HB; Poulsen CB; Kjaer-Sorensen K; Gyrup C; Oxvig C
    J Biol Chem; 2007 Apr; 282(15):10988-99. PubMed ID: 17314100
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Definition, expression, and characterization of a protein domain in the N-terminus of pregnancy-associated plasma protein-A distantly related to the family of laminin G-like modules.
    Boldt HB; Glerup S; Overgaard MT; Sottrup-Jensen L; Oxvig C
    Protein Expr Purif; 2006 Aug; 48(2):261-73. PubMed ID: 16529943
    [TBL] [Abstract][Full Text] [Related]  

  • 6. IGF dependent modulation of IGF binding protein (IGFBP) proteolysis by pregnancy-associated plasma protein-A (PAPP-A): multiple PAPP-A-IGFBP interaction sites.
    Gaidamauskas E; Gyrup C; Boldt HB; Schack VR; Overgaard MT; Laursen LS; Oxvig C
    Biochim Biophys Acta; 2013 Mar; 1830(3):2701-9. PubMed ID: 23671931
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Inhibition of the proteolytic activity of pregnancy-associated plasma protein-A by targeting substrate exosite binding.
    Mikkelsen JH; Gyrup C; Kristensen P; Overgaard MT; Poulsen CB; Laursen LS; Oxvig C
    J Biol Chem; 2008 Jun; 283(24):16772-80. PubMed ID: 18434323
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The Lin12-notch repeats of pregnancy-associated plasma protein-A bind calcium and determine its proteolytic specificity.
    Boldt HB; Kjaer-Sorensen K; Overgaard MT; Weyer K; Poulsen CB; Sottrup-Jensen L; Conover CA; Giudice LC; Oxvig C
    J Biol Chem; 2004 Sep; 279(37):38525-31. PubMed ID: 15262980
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Pregnancy-associated plasma protein-A2 (PAPP-A2), a novel insulin-like growth factor-binding protein-5 proteinase.
    Overgaard MT; Boldt HB; Laursen LS; Sottrup-Jensen L; Conover CA; Oxvig C
    J Biol Chem; 2001 Jun; 276(24):21849-53. PubMed ID: 11264294
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Complex of pregnancy-associated plasma protein-A and the proform of eosinophil major basic protein. Disulfide structure and carbohydrate attachment.
    Overgaard MT; Sorensen ES; Stachowiak D; Boldt HB; Kristensen L; Sottrup-Jensen L; Oxvig C
    J Biol Chem; 2003 Jan; 278(4):2106-17. PubMed ID: 12421832
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Mutational analysis of the proteolytic domain of pregnancy-associated plasma protein-A (PAPP-A): classification as a metzincin.
    Boldt HB; Overgaard MT; Laursen LS; Weyer K; Sottrup-Jensen L; Oxvig C
    Biochem J; 2001 Sep; 358(Pt 2):359-67. PubMed ID: 11513734
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Inhibition of proteolysis by the proform of eosinophil major basic protein (proMBP) requires covalent binding to its target proteinase.
    Overgaard MT; Glerup S; Boldt HB; Rodacker V; Olsen IM; Christiansen M; Sottrup-Jensen L; Giudice LC; Oxvig C
    FEBS Lett; 2004 Feb; 560(1-3):147-52. PubMed ID: 14988014
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Expression of recombinant murine pregnancy-associated plasma protein-A (PAPP-A) and a novel variant (PAPP-Ai) with differential proteolytic activity.
    Søe R; Overgaard MT; Thomsen AR; Laursen LS; Olsen IM; Sottrup-Jensen L; Haaning J; Giudice LC; Conover CA; Oxvig C
    Eur J Biochem; 2002 Apr; 269(8):2247-56. PubMed ID: 11985604
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Interactions of the basic N-terminal and the acidic C-terminal domains of the maize chromosomal HMGB1 protein.
    Thomsen MS; Franssen L; Launholt D; Fojan P; Grasser KD
    Biochemistry; 2004 Jun; 43(25):8029-37. PubMed ID: 15209498
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Pregnancy-associated plasma protein A proteolytic activity is associated with the human placental trophoblast cell membrane.
    Sun IY; Overgaard MT; Oxvig C; Giudice LC
    J Clin Endocrinol Metab; 2002 Nov; 87(11):5235-40. PubMed ID: 12414897
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Cell surface detachment of pregnancy-associated plasma protein-A requires the formation of intermolecular proteinase-inhibitor disulfide bonds and glycosaminoglycan covalently bound to the inhibitor.
    Glerup S; Kløverpris S; Laursen LS; Dagnaes-Hansen F; Thiel S; Conover CA; Oxvig C
    J Biol Chem; 2007 Jan; 282(3):1769-78. PubMed ID: 17145752
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Heparin-binding, highly basic regions within the thyroglobulin type-1 repeat of insulin-like growth factor (IGF)-binding proteins (IGFBPs) -3, -5, and -6 inhibit IGFBP-4 degradation.
    Fowlkes JL; Thrailkill KM; George-Nascimento C; Rosenberg CK; Serra DM
    Endocrinology; 1997 Jun; 138(6):2280-5. PubMed ID: 9165012
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The Kaposi's sarcoma-associated herpesvirus complement control protein (KCP) binds to heparin and cell surfaces via positively charged amino acids in CCP1-2.
    Mark L; Lee WH; Spiller OB; Villoutreix BO; Blom AM
    Mol Immunol; 2006 Apr; 43(10):1665-75. PubMed ID: 16442624
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Pregnancy-associated plasma protein-A (PAPP-A): a local regulator of IGF bioavailability through cleavage of IGFBPs.
    Boldt HB; Conover CA
    Growth Horm IGF Res; 2007 Feb; 17(1):10-8. PubMed ID: 17218136
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Covalent interaction between proform of eosinophil major basic protein (proMBP) and pregnancy-associated plasma protein-A (PAPP-A) is a cell-mediated event and required for proMBP inhibition of the catalytic activity of PAPP-A.
    Sivanandam AS; Mohan S; Kapur S; Kita H; Lau KH; Bagi G; Baylink DJ; Qin X
    Arch Biochem Biophys; 2004 Mar; 423(2):343-50. PubMed ID: 15001398
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.