BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

165 related articles for article (PubMed ID: 15070696)

  • 1. Rapamycin sensitizes multiple myeloma cells to apoptosis induced by dexamethasone.
    Strömberg T; Dimberg A; Hammarberg A; Carlson K; Osterborg A; Nilsson K; Jernberg-Wiklund H
    Blood; 2004 Apr; 103(8):3138-47. PubMed ID: 15070696
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Mechanism by which mammalian target of rapamycin inhibitors sensitize multiple myeloma cells to dexamethasone-induced apoptosis.
    Yan H; Frost P; Shi Y; Hoang B; Sharma S; Fisher M; Gera J; Lichtenstein A
    Cancer Res; 2006 Feb; 66(4):2305-13. PubMed ID: 16489035
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Targeting mTOR/p70S6K/glycolysis signaling pathway restores glucocorticoid sensitivity to 4E-BP1 null Burkitt Lymphoma.
    Gu L; Xie L; Zuo C; Ma Z; Zhang Y; Zhu Y; Gao J
    BMC Cancer; 2015 Jul; 15():529. PubMed ID: 26189041
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Mammalian target of rapamycin inhibitors activate the AKT kinase in multiple myeloma cells by up-regulating the insulin-like growth factor receptor/insulin receptor substrate-1/phosphatidylinositol 3-kinase cascade.
    Shi Y; Yan H; Frost P; Gera J; Lichtenstein A
    Mol Cancer Ther; 2005 Oct; 4(10):1533-40. PubMed ID: 16227402
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Rapamycin-induced G1 arrest in cycling B-CLL cells is associated with reduced expression of cyclin D3, cyclin E, cyclin A, and survivin.
    Decker T; Hipp S; Ringshausen I; Bogner C; Oelsner M; Schneller F; Peschel C
    Blood; 2003 Jan; 101(1):278-85. PubMed ID: 12393642
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Receptor synergy of interleukin-6 (IL-6) and insulin-like growth factor-I in myeloma cells that highly express IL-6 receptor alpha [corrected].
    Abroun S; Ishikawa H; Tsuyama N; Liu S; Li FJ; Otsuyama K; Zheng X; Obata M; Kawano MM
    Blood; 2004 Mar; 103(6):2291-8. PubMed ID: 14592826
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Role of the phosphatidylinositol 3-kinase/Akt and mTOR/P70S6-kinase pathways in the proliferation and apoptosis in multiple myeloma.
    Pene F; Claessens YE; Muller O; Viguié F; Mayeux P; Dreyfus F; Lacombe C; Bouscary D
    Oncogene; 2002 Sep; 21(43):6587-97. PubMed ID: 12242656
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Control of apoptosis in human multiple myeloma by insulin-like growth factor I (IGF-I).
    Jernberg-Wiklund H; Nilsson K
    Adv Cancer Res; 2007; 97():139-65. PubMed ID: 17419944
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Rapamycin sensitizes T-ALL cells to dexamethasone-induced apoptosis.
    Gu L; Zhou C; Liu H; Gao J; Li Q; Mu D; Ma Z
    J Exp Clin Cancer Res; 2010 Nov; 29(1):150. PubMed ID: 21083937
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Rapamycin-mediated mTOR inhibition attenuates survivin and sensitizes glioblastoma cells to radiation therapy.
    Anandharaj A; Cinghu S; Park WY
    Acta Biochim Biophys Sin (Shanghai); 2011 Apr; 43(4):292-300. PubMed ID: 21367753
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Mechanism of ribosomal p70S6 kinase activation by granulocyte macrophage colony-stimulating factor in neutrophils: cooperation of a MEK-related, THR421/SER424 kinase and a rapamycin-sensitive, m-TOR-related THR389 kinase.
    Lehman JA; Calvo V; Gomez-Cambronero J
    J Biol Chem; 2003 Jul; 278(30):28130-8. PubMed ID: 12740386
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Requirement of ClC-3 in G0/G1 to S Phase Transition Induced by IGF-1 via ERK1/2-Cyclins Cascade in Multiple Myeloma Cells.
    Du Y; Tu YS; Tang YB; Huang YY; Zhou FM; Tian T; Li XY
    Clin Lab; 2018 Jun; 64(6):929-936. PubMed ID: 29945325
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Longitudinal inhibition of PI3K/Akt/mTOR signaling by LY294002 and rapamycin induces growth arrest of adult T-cell leukemia cells.
    Ikezoe T; Nishioka C; Bandobashi K; Yang Y; Kuwayama Y; Adachi Y; Takeuchi T; Koeffler HP; Taguchi H
    Leuk Res; 2007 May; 31(5):673-82. PubMed ID: 17007924
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Molecular mechanisms underlying interferon-alpha-induced G0/G1 arrest: CKI-mediated regulation of G1 Cdk-complexes and activation of pocket proteins.
    Sangfelt O; Erickson S; Castro J; Heiden T; Gustafsson A; Einhorn S; Grandér D
    Oncogene; 1999 May; 18(18):2798-810. PubMed ID: 10362250
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Mammalian target of rapamycin inhibitors rapamycin and RAD001 (everolimus) induce anti-proliferative effects in GH-secreting pituitary tumor cells in vitro.
    Gorshtein A; Rubinfeld H; Kendler E; Theodoropoulou M; Cerovac V; Stalla GK; Cohen ZR; Hadani M; Shimon I
    Endocr Relat Cancer; 2009 Sep; 16(3):1017-27. PubMed ID: 19509067
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Simultaneous targeting of PI3K and mTOR with NVP-BGT226 is highly effective in multiple myeloma.
    Baumann P; Schneider L; Mandl-Weber S; Oduncu F; Schmidmaier R
    Anticancer Drugs; 2012 Jan; 23(1):131-8. PubMed ID: 21959532
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Cell cycle progression of chronic lymphocytic leukemia cells is controlled by cyclin D2, cyclin D3, cyclin-dependent kinase (cdk) 4 and the cdk inhibitor p27.
    Decker T; Schneller F; Hipp S; Miething C; Jahn T; Duyster J; Peschel C
    Leukemia; 2002 Mar; 16(3):327-34. PubMed ID: 11896535
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Rapamycin reverses NPM-ALK-induced glucocorticoid resistance in lymphoid tumor cells by inhibiting mTOR signaling pathway, enhancing G1 cell cycle arrest and apoptosis.
    Gu L; Gao J; Li Q; Zhu YP; Jia CS; Fu RY; Chen Y; Liao QK; Ma Z
    Leukemia; 2008 Nov; 22(11):2091-6. PubMed ID: 18685609
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Synergistic induction of oxidative injury and apoptosis in human multiple myeloma cells by the proteasome inhibitor bortezomib and histone deacetylase inhibitors.
    Pei XY; Dai Y; Grant S
    Clin Cancer Res; 2004 Jun; 10(11):3839-52. PubMed ID: 15173093
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The novel orally bioavailable inhibitor of phosphoinositol-3-kinase and mammalian target of rapamycin, NVP-BEZ235, inhibits growth and proliferation in multiple myeloma.
    Baumann P; Mandl-Weber S; Oduncu F; Schmidmaier R
    Exp Cell Res; 2009 Feb; 315(3):485-97. PubMed ID: 19071109
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.