105 related articles for article (PubMed ID: 15075665)
1. The Brk protein tyrosine kinase as a therapeutic target in cancer: opportunities and challenges.
Harvey AJ; Crompton MR
Anticancer Drugs; 2004 Feb; 15(2):107-11. PubMed ID: 15075665
[TBL] [Abstract][Full Text] [Related]
2. Putting the BRK on breast cancer: From molecular target to therapeutics.
Ang HL; Yuan Y; Lai X; Tan TZ; Wang L; Huang BB; Pandey V; Huang RY; Lobie PE; Goh BC; Sethi G; Yap CT; Chan CW; Lee SC; Kumar AP
Theranostics; 2021; 11(3):1115-1128. PubMed ID: 33391524
[TBL] [Abstract][Full Text] [Related]
3. BRK tyrosine kinase expression in a high proportion of human breast carcinomas.
Barker KT; Jackson LE; Crompton MR
Oncogene; 1997 Aug; 15(7):799-805. PubMed ID: 9266966
[TBL] [Abstract][Full Text] [Related]
4. Tracing the footprints of the breast cancer oncogene BRK - Past till present.
Goel RK; Lukong KE
Biochim Biophys Acta; 2015 Aug; 1856(1):39-54. PubMed ID: 25999240
[TBL] [Abstract][Full Text] [Related]
5. Use of RNA interference to validate Brk as a novel therapeutic target in breast cancer: Brk promotes breast carcinoma cell proliferation.
Harvey AJ; Crompton MR
Oncogene; 2003 Aug; 22(32):5006-10. PubMed ID: 12902983
[TBL] [Abstract][Full Text] [Related]
6. Breast tumor kinase (protein tyrosine kinase 6) regulates heregulin-induced activation of ERK5 and p38 MAP kinases in breast cancer cells.
Ostrander JH; Daniel AR; Lofgren K; Kleer CG; Lange CA
Cancer Res; 2007 May; 67(9):4199-209. PubMed ID: 17483331
[TBL] [Abstract][Full Text] [Related]
7. Expression of the BRK tyrosine kinase in mammary epithelial cells enhances the coupling of EGF signalling to PI 3-kinase and Akt, via erbB3 phosphorylation.
Kamalati T; Jolin HE; Fry MJ; Crompton MR
Oncogene; 2000 Nov; 19(48):5471-6. PubMed ID: 11114724
[TBL] [Abstract][Full Text] [Related]
8. Breast tumor kinase phosphorylates p190RhoGAP to regulate rho and ras and promote breast carcinoma growth, migration, and invasion.
Shen CH; Chen HY; Lin MS; Li FY; Chang CC; Kuo ML; Settleman J; Chen RH
Cancer Res; 2008 Oct; 68(19):7779-87. PubMed ID: 18829532
[TBL] [Abstract][Full Text] [Related]
9. Deregulation of the cell cycle by breast tumor kinase (Brk).
Chan E; Nimnual AS
Int J Cancer; 2010 Dec; 127(11):2723-31. PubMed ID: 20162673
[TBL] [Abstract][Full Text] [Related]
10. Brk/PTK6 signaling in normal and cancer cell models.
Ostrander JH; Daniel AR; Lange CA
Curr Opin Pharmacol; 2010 Dec; 10(6):662-9. PubMed ID: 20832360
[TBL] [Abstract][Full Text] [Related]
11. Targeting BRK-Positive Breast Cancers with Small-Molecule Kinase Inhibitors.
Jiang J; Gui F; He Z; Li L; Li Y; Li S; Wu X; Deng Z; Sun X; Huang X; Huang W; Han S; Zhang T; Wang Z; Jiao B; Song S; Wang H; Chen L; Zhou D; Liu Q; Ren R; Zhang J; Deng X
Cancer Res; 2017 Jan; 77(1):175-186. PubMed ID: 27758886
[TBL] [Abstract][Full Text] [Related]
12. Breast tumor kinase/protein tyrosine kinase 6 (Brk/PTK6) activity in normal and neoplastic biliary epithelia.
Mizuguchi Y; Specht S; Isse K; Sasatomi E; Lunz JG; Takizawa T; Demetris AJ
J Hepatol; 2015 Aug; 63(2):399-407. PubMed ID: 25770659
[TBL] [Abstract][Full Text] [Related]
13. Cloning and characterisation of cDNAs encoding a novel non-receptor tyrosine kinase, brk, expressed in human breast tumours.
Mitchell PJ; Barker KT; Martindale JE; Kamalati T; Lowe PN; Page MJ; Gusterson BA; Crompton MR
Oncogene; 1994 Aug; 9(8):2383-90. PubMed ID: 8036022
[TBL] [Abstract][Full Text] [Related]
14. Cancer-Associated Mutations in Breast Tumor Kinase/PTK6 Differentially Affect Enzyme Activity and Substrate Recognition.
Tsui T; Miller WT
Biochemistry; 2015 May; 54(20):3173-82. PubMed ID: 25940761
[TBL] [Abstract][Full Text] [Related]
15. Dual Inhibition of CDK4 and CDK2 via Targeting p27 Tyrosine Phosphorylation Induces a Potent and Durable Response in Breast Cancer Cells.
Patel P; Tsiperson V; Gottesman SRS; Somma J; Blain SW
Mol Cancer Res; 2018 Mar; 16(3):361-377. PubMed ID: 29330290
[TBL] [Abstract][Full Text] [Related]
16. BRK phosphorylates PSF promoting its cytoplasmic localization and cell cycle arrest.
Lukong KE; Huot ME; Richard S
Cell Signal; 2009 Sep; 21(9):1415-22. PubMed ID: 19439179
[TBL] [Abstract][Full Text] [Related]
17. Characterisation and chromosome mapping of the human non receptor tyrosine kinase gene, brk.
Mitchell PJ; Barker KT; Shipley J; Crompton MR
Oncogene; 1997 Sep; 15(12):1497-502. PubMed ID: 9333026
[TBL] [Abstract][Full Text] [Related]
18. Discovery of novel imidazo[1,2-a]pyrazin-8-amines as Brk/PTK6 inhibitors.
Zeng H; Belanger DB; Curran PJ; Shipps GW; Miao H; Bracken JB; Arshad Siddiqui M; Malkowski M; Wang Y
Bioorg Med Chem Lett; 2011 Oct; 21(19):5870-5. PubMed ID: 21855335
[TBL] [Abstract][Full Text] [Related]
19. Small molecule inhibitors reveal PTK6 kinase is not an oncogenic driver in breast cancers.
Qiu L; Levine K; Gajiwala KS; Cronin CN; Nagata A; Johnson E; Kraus M; Tatlock J; Kania R; Foley T; Sun S
PLoS One; 2018; 13(6):e0198374. PubMed ID: 29879184
[TBL] [Abstract][Full Text] [Related]
20. Identification of STAT3 as a specific substrate of breast tumor kinase.
Liu L; Gao Y; Qiu H; Miller WT; Poli V; Reich NC
Oncogene; 2006 Aug; 25(35):4904-12. PubMed ID: 16568091
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
