BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

158 related articles for article (PubMed ID: 15077183)

  • 1. The PAX8/PPARgamma fusion oncoprotein transforms immortalized human thyrocytes through a mechanism probably involving wild-type PPARgamma inhibition.
    Gregory Powell J; Wang X; Allard BL; Sahin M; Wang XL; Hay ID; Hiddinga HJ; Deshpande SS; Kroll TG; Grebe SK; Eberhardt NL; McIver B
    Oncogene; 2004 Apr; 23(20):3634-41. PubMed ID: 15077183
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Proteomic analysis of differentially expressed proteins in normal human thyroid cells transfected with PPFP.
    Li X; Wang Z; Liu J; Tang C; Duan C; Li C
    Endocr Relat Cancer; 2012 Oct; 19(5):681-94. PubMed ID: 22903648
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The PAX8/PPAR gamma fusion oncogene as a potential therapeutic target in follicular thyroid carcinoma.
    McIver B; Grebe SK; Eberhardt NL
    Curr Drug Targets Immune Endocr Metabol Disord; 2004 Sep; 4(3):221-34. PubMed ID: 15379724
    [TBL] [Abstract][Full Text] [Related]  

  • 4. PAX8PPARgamma stimulates cell viability and modulates expression of thyroid-specific genes in a human thyroid cell line.
    Espadinha C; Cavaco BM; Leite V
    Thyroid; 2007 Jun; 17(6):497-509. PubMed ID: 17614769
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Adipogenic Differentiation of Thyroid Cancer Cells Through the Pax8-PPARγ Fusion Protein Is Regulated by Thyroid Transcription Factor 1 (TTF-1).
    Xu B; O'Donnell M; O'Donnell J; Yu J; Zhang Y; Sartor MA; Koenig RJ
    J Biol Chem; 2016 Sep; 291(37):19274-86. PubMed ID: 27435678
    [TBL] [Abstract][Full Text] [Related]  

  • 6. PAX8-peroxisome proliferator-activated receptor gamma (PPARgamma) disrupts normal PAX8 or PPARgamma transcriptional function and stimulates follicular thyroid cell growth.
    Au AY; McBride C; Wilhelm KG; Koenig RJ; Speller B; Cheung L; Messina M; Wentworth J; Tasevski V; Learoyd D; Robinson BG; Clifton-Bligh RJ
    Endocrinology; 2006 Jan; 147(1):367-76. PubMed ID: 16179407
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The expression of PAX8-PPARgamma rearrangements is not specific to follicular thyroid carcinoma.
    Nakabashi CC; Guimarães GS; Michaluart P; Ward LS; Cerutti JM; Maciel RM
    Clin Endocrinol (Oxf); 2004 Aug; 61(2):280-2. PubMed ID: 15272927
    [No Abstract]   [Full Text] [Related]  

  • 8. Delineation, functional validation, and bioinformatic evaluation of gene expression in thyroid follicular carcinomas with the PAX8-PPARG translocation.
    Giordano TJ; Au AY; Kuick R; Thomas DG; Rhodes DR; Wilhelm KG; Vinco M; Misek DE; Sanders D; Zhu Z; Ciampi R; Hanash S; Chinnaiyan A; Clifton-Bligh RJ; Robinson BG; Nikiforov YE; Koenig RJ
    Clin Cancer Res; 2006 Apr; 12(7 Pt 1):1983-93. PubMed ID: 16609007
    [TBL] [Abstract][Full Text] [Related]  

  • 9. PAX8-PPARgamma rearrangement in thyroid tumors: RT-PCR and immunohistochemical analyses.
    Nikiforova MN; Biddinger PW; Caudill CM; Kroll TG; Nikiforov YE
    Am J Surg Pathol; 2002 Aug; 26(8):1016-23. PubMed ID: 12170088
    [TBL] [Abstract][Full Text] [Related]  

  • 10. PPARgamma staining as a surrogate for PAX8/PPARgamma fusion oncogene expression in follicular neoplasms: clinicopathological correlation and histopathological diagnostic value.
    Sahin M; Allard BL; Yates M; Powell JG; Wang XL; Hay ID; Zhao Y; Goellner JR; Sebo TJ; Grebe SK; Eberhardt NL; McIver B
    J Clin Endocrinol Metab; 2005 Jan; 90(1):463-8. PubMed ID: 15483076
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Expression of PAX8-PPAR gamma 1 rearrangements in both follicular thyroid carcinomas and adenomas.
    Marques AR; Espadinha C; Catarino AL; Moniz S; Pereira T; Sobrinho LG; Leite V
    J Clin Endocrinol Metab; 2002 Aug; 87(8):3947-52. PubMed ID: 12161538
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Thyroid transcription factor 1 rescues PAX8/p300 synergism impaired by a natural PAX8 paired domain mutation with dominant negative activity.
    Grasberger H; Ringkananont U; Lefrancois P; Abramowicz M; Vassart G; Refetoff S
    Mol Endocrinol; 2005 Jul; 19(7):1779-91. PubMed ID: 15718293
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The Putative PAX8/PPARγ Fusion Oncoprotein Exhibits Partial Tumor Suppressor Activity through Up-Regulation of Micro-RNA-122 and Dominant-Negative PPARγ Activity.
    Reddi HV; Madde P; Milosevic D; Hackbarth JS; Algeciras-Schimnich A; McIver B; Grebe SK; Eberhardt NL
    Genes Cancer; 2011 Jan; 2(1):46-55. PubMed ID: 21779480
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Paired box gene 8-peroxisome proliferator-activated receptor-gamma fusion protein and loss of phosphatase and tensin homolog synergistically cause thyroid hyperplasia in transgenic mice.
    Diallo-Krou E; Yu J; Colby LA; Inoki K; Wilkinson JE; Thomas DG; Giordano TJ; Koenig RJ
    Endocrinology; 2009 Nov; 150(11):5181-90. PubMed ID: 19797117
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Pioglitazone induces a proadipogenic antitumor response in mice with PAX8-PPARgamma fusion protein thyroid carcinoma.
    Dobson ME; Diallo-Krou E; Grachtchouk V; Yu J; Colby LA; Wilkinson JE; Giordano TJ; Koenig RJ
    Endocrinology; 2011 Nov; 152(11):4455-65. PubMed ID: 21952241
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Expression of the PAX8/PPARγ Fusion Protein Is Associated with Decreased Neovascularization In Vivo: Impact on Tumorigenesis and Disease Prognosis.
    Reddi HV; Madde P; Marlow LA; Copland JA; McIver B; Grebe SK; Eberhardt NL
    Genes Cancer; 2010 May; 1(5):480-492. PubMed ID: 20827445
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Follicular cells of the thyroid gland require Pax8 gene function.
    Mansouri A; Chowdhury K; Gruss P
    Nat Genet; 1998 May; 19(1):87-90. PubMed ID: 9590297
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Detection of the PAX8-PPAR gamma fusion oncogene in both follicular thyroid carcinomas and adenomas.
    Cheung L; Messina M; Gill A; Clarkson A; Learoyd D; Delbridge L; Wentworth J; Philips J; Clifton-Bligh R; Robinson BG
    J Clin Endocrinol Metab; 2003 Jan; 88(1):354-7. PubMed ID: 12519876
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Genomic binding and regulation of gene expression by the thyroid carcinoma-associated PAX8-PPARG fusion protein.
    Zhang Y; Yu J; Lee C; Xu B; Sartor MA; Koenig RJ
    Oncotarget; 2015 Dec; 6(38):40418-32. PubMed ID: 26595524
    [TBL] [Abstract][Full Text] [Related]  

  • 20. PAX8-PPARgamma1 fusion oncogene in human thyroid carcinoma [corrected].
    Kroll TG; Sarraf P; Pecciarini L; Chen CJ; Mueller E; Spiegelman BM; Fletcher JA
    Science; 2000 Aug; 289(5483):1357-60. PubMed ID: 10958784
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.