BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

143 related articles for article (PubMed ID: 15084985)

  • 1. Role of the phosphatidylinositol 3'-kinase-Akt signal pathway in the proliferation of human pancreatic ductal carcinoma cell lines.
    Takeda A; Osaki M; Adachi K; Honjo S; Ito H
    Pancreas; 2004 Apr; 28(3):353-8. PubMed ID: 15084985
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Inhibition of the PI3K-Akt signaling pathway enhances the sensitivity of Fas-mediated apoptosis in human gastric carcinoma cell line, MKN-45.
    Osaki M; Kase S; Adachi K; Takeda A; Hashimoto K; Ito H
    J Cancer Res Clin Oncol; 2004 Jan; 130(1):8-14. PubMed ID: 14605879
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Phosphorylated Akt/PKB controls cell growth and apoptosis in intraductal papillary-mucinous tumor and invasive ductal adenocarcinoma of the pancreas.
    Semba S; Moriya T; Kimura W; Yamakawa M
    Pancreas; 2003 Apr; 26(3):250-7. PubMed ID: 12657951
    [TBL] [Abstract][Full Text] [Related]  

  • 4. BCR signals target p27(Kip1) and cyclin D2 via the PI3-K signalling pathway to mediate cell cycle arrest and apoptosis of WEHI 231 B cells.
    Banerji L; Glassford J; Lea NC; Thomas NS; Klaus GG; Lam EW
    Oncogene; 2001 Nov; 20(50):7352-67. PubMed ID: 11704865
    [TBL] [Abstract][Full Text] [Related]  

  • 5. BCR/ABL regulates expression of the cyclin-dependent kinase inhibitor p27Kip1 through the phosphatidylinositol 3-Kinase/AKT pathway.
    Gesbert F; Sellers WR; Signoretti S; Loda M; Griffin JD
    J Biol Chem; 2000 Dec; 275(50):39223-30. PubMed ID: 11010972
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Regulation of cell apoptosis and proliferation in pancreatic cancer through PI3K/Akt pathway via Polo-like kinase 1.
    Mao Y; Xi L; Li Q; Cai Z; Lai Y; Zhang X; Yu C
    Oncol Rep; 2016 Jul; 36(1):49-56. PubMed ID: 27220401
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Cooperative regulation of the cell division cycle by the protein kinases RAF and AKT.
    Mirza AM; Gysin S; Malek N; Nakayama K; Roberts JM; McMahon M
    Mol Cell Biol; 2004 Dec; 24(24):10868-81. PubMed ID: 15572689
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The in vitro and in vivo effects of 2-(4-morpholinyl)-8-phenyl-chromone (LY294002), a specific inhibitor of phosphatidylinositol 3'-kinase, in human colon cancer cells.
    Semba S; Itoh N; Ito M; Harada M; Yamakawa M
    Clin Cancer Res; 2002 Jun; 8(6):1957-63. PubMed ID: 12060641
    [TBL] [Abstract][Full Text] [Related]  

  • 9. ErbB2/neu kinase modulates cellular p27(Kip1) and cyclin D1 through multiple signaling pathways.
    Lenferink AE; Busse D; Flanagan WM; Yakes FM; Arteaga CL
    Cancer Res; 2001 Sep; 61(17):6583-91. PubMed ID: 11522658
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Inhibition of phosphatidylinositol 3'-kinase/AKT signaling promotes apoptosis of primary effusion lymphoma cells.
    Uddin S; Hussain AR; Al-Hussein KA; Manogaran PS; Wickrema A; Gutierrez MI; Bhatia KG
    Clin Cancer Res; 2005 Apr; 11(8):3102-8. PubMed ID: 15837766
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Role of the phosphatidylinositol 3-kinase/Akt and mTOR/P70S6-kinase pathways in the proliferation and apoptosis in multiple myeloma.
    Pene F; Claessens YE; Muller O; ViguiƩ F; Mayeux P; Dreyfus F; Lacombe C; Bouscary D
    Oncogene; 2002 Sep; 21(43):6587-97. PubMed ID: 12242656
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Epidermal growth factor induces HCCR expression via PI3K/Akt/mTOR signaling in PANC-1 pancreatic cancer cells.
    Xu Z; Zhang Y; Jiang J; Yang Y; Shi R; Hao B; Zhang Z; Huang Z; Kim JW; Zhang G
    BMC Cancer; 2010 Apr; 10():161. PubMed ID: 20423485
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Phosphoinositide-3-kinase signaling controls S-phase kinase-associated protein 2 transcription via E2F1 in pancreatic ductal adenocarcinoma cells.
    Reichert M; Saur D; Hamacher R; Schmid RM; Schneider G
    Cancer Res; 2007 May; 67(9):4149-56. PubMed ID: 17483325
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Inhibition of the phosphatidylinositol 3'-kinase signaling pathway increases the responsiveness of pancreatic carcinoma cells to sulindac.
    Yip-Schneider MT; Wiesenauer CA; Schmidt CM
    J Gastrointest Surg; 2003; 7(3):354-63. PubMed ID: 12654560
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Role of PI3K signaling in survival and progression of LNCaP prostate cancer cells to the androgen refractory state.
    Murillo H; Huang H; Schmidt LJ; Smith DI; Tindall DJ
    Endocrinology; 2001 Nov; 142(11):4795-805. PubMed ID: 11606446
    [TBL] [Abstract][Full Text] [Related]  

  • 16. PTEN/MMAC1/TEP1 suppresses the tumorigenicity and induces G1 cell cycle arrest in human glioblastoma cells.
    Li DM; Sun H
    Proc Natl Acad Sci U S A; 1998 Dec; 95(26):15406-11. PubMed ID: 9860981
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Inhibition of activated phosphatidylinositol 3-kinase/AKT pathway in malignant pleural mesothelioma leads to G1 cell cycle arrest.
    Mikami I; Zhang F; Hirata T; Okamoto J; Koizumi K; Shimizu K; Jablons D; He B
    Oncol Rep; 2010 Dec; 24(6):1677-81. PubMed ID: 21042767
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Selective protection of mitogenically stimulated human lymphocytes but not leukemic cells from cytosine arabinoside-induced apoptosis by LY294002, a phosphoinositol-3 kinase inhibitor.
    Du L; Smolewski P; Bedner E; Traganos F; Darzynkiewicz Z
    Int J Oncol; 2001 Oct; 19(4):811-9. PubMed ID: 11562760
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Inhibition of phosphatidylinositol-3-kinase causes cell death through a protein kinase B (PKB)-dependent mechanism and growth arrest through a PKB-independent mechanism.
    Gottschalk AR; Doan A; Nakamura JL; Haas-Kogan DA; Stokoe D
    Int J Radiat Oncol Biol Phys; 2005 Mar; 61(4):1183-8. PubMed ID: 15752900
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Cotargeting of epidermal growth factor receptor and PI3K overcomes PI3K-Akt oncogenic dependence in pancreatic ductal adenocarcinoma.
    Wong MH; Xue A; Julovi SM; Pavlakis N; Samra JS; Hugh TJ; Gill AJ; Peters L; Baxter RC; Smith RC
    Clin Cancer Res; 2014 Aug; 20(15):4047-58. PubMed ID: 24895459
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.