These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

96 related articles for article (PubMed ID: 15093185)

  • 1. Long-term lowering of plasma cholesterol levels in LDL-receptor-deficient WHHL rabbits by gene therapy.
    Kankkonen HM; Vähäkangas E; Marr RA; Pakkanen T; Laurema A; Leppänen P; Jalkanen J; Verma IM; Ylä-Herttuala S
    Mol Ther; 2004 Apr; 9(4):548-56. PubMed ID: 15093185
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Long-term reversal of hypercholesterolemia in low density lipoprotein receptor (LDLR)-deficient mice by adenovirus-mediated LDLR gene transfer combined with CD154 blockade.
    Stein CS; Martins I; Davidson BL
    J Gene Med; 2000; 2(1):41-51. PubMed ID: 10765504
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Enhanced plasma cholesterol lowering effect of retrovirus-mediated LDL receptor gene transfer to WHHL rabbit liver after improved surgical technique and stimulation of hepatocyte proliferation by combined partial liver resection and thymidine kinase--ganciclovir treatment.
    Pakkanen TM; Laitinen M; Hippeläinen M; Kallionpää H; Lehtolainen P; Leppänen P; Luoma JS; Tarvainen R; Alhava E; Ylä-Herttuala S
    Gene Ther; 1999 Jan; 6(1):34-41. PubMed ID: 10341873
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Sleeping Beauty Transposon Vectors in Liver-directed Gene Delivery of LDLR and VLDLR for Gene Therapy of Familial Hypercholesterolemia.
    Turunen TA; Kurkipuro J; Heikura T; Vuorio T; Hytönen E; Izsvák Z; Ylä-Herttuala S
    Mol Ther; 2016 Mar; 24(3):620-35. PubMed ID: 26670130
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A sensitive noninvasive method for monitoring successful liver-directed gene transfer of the low-density lipoprotein receptor in Watanabe hyperlipidemic rabbits in vivo.
    Tietge UJ; Cichon G; Büttner C; Genschel J; Heeren J; Gielow P; Grewe N; Dogar M; Beisiegel U; Manns MP; Lochs H; Burchert W; Schmidt HH
    Gene Ther; 2004 Apr; 11(7):574-80. PubMed ID: 14724675
    [TBL] [Abstract][Full Text] [Related]  

  • 6. In vivo gene therapy for hyperlipidemia: phenotypic correction in Watanabe rabbits by hepatic delivery of the rabbit LDL receptor gene.
    Li J; Fang B; Eisensmith RC; Li XH; Nasonkin I; Lin-Lee YC; Mims MP; Hughes A; Montgomery CD; Roberts JD
    J Clin Invest; 1995 Feb; 95(2):768-73. PubMed ID: 7860759
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Bile-duct proliferation as an unexpected side-effect after AAV2-LDLR gene transfer to rabbit liver.
    Hytönen E; Laurema A; Kankkonen H; Miyanohara A; Kärjä V; Hujo M; Laham-Karam N; Ylä-Herttuala S
    Sci Rep; 2019 May; 9(1):6934. PubMed ID: 31061510
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Improving lipoprotein profiles by liver-directed gene transfer of low density lipoprotein receptor gene in hypercholesterolaemia mice.
    Ou H; Zhang Q; Zeng J
    J Genet; 2016 Jun; 95(2):311-6. PubMed ID: 27350674
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Non-physiological overexpression of the low density lipoprotein receptor (LDLr) gene in the liver induces pathological intracellular lipid and cholesterol storage.
    Cichon G; Willnow T; Herwig S; Uckert W; Löser P; Schmidt HH; Benhidjeb T; Schlag PM; Schnieders F; Niedzielska D; Heeren J
    J Gene Med; 2004 Feb; 6(2):166-75. PubMed ID: 14978770
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Correction of the genetic defect in hepatocytes from the Watanabe heritable hyperlipidemic rabbit.
    Wilson JM; Johnston DE; Jefferson DM; Mulligan RC
    Proc Natl Acad Sci U S A; 1988 Jun; 85(12):4421-5. PubMed ID: 2454468
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Unexpected inhibition of cholesterol 7 alpha-hydroxylase by cholesterol in New Zealand white and Watanabe heritable hyperlipidemic rabbits.
    Xu G; Salen G; Shefer S; Ness GC; Nguyen LB; Parker TS; Chen TS; Zhao Z; Donnelly TM; Tint GS
    J Clin Invest; 1995 Apr; 95(4):1497-504. PubMed ID: 7706454
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Ex vivo gene therapy of familial hypercholesterolemia.
    Wilson JM; Grossman M; Raper SE; Baker JR; Newton RS; Thoene JG
    Hum Gene Ther; 1992 Apr; 3(2):179-222. PubMed ID: 1391038
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Hepatocyte transplantation for the low-density lipoprotein receptor-deficient state. A study in the Watanabe rabbit.
    Wiederkehr JC; Kondos GT; Pollak R
    Transplantation; 1990 Sep; 50(3):466-71. PubMed ID: 2144923
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Improved Hepatocyte Engraftment After Portal Vein Occlusion in LDL Receptor-Deficient WHHL Rabbits and Lentiviral-Mediated Phenotypic Correction In Vitro.
    Goulinet-Mainot S; Tranchart H; Groyer-Picard MT; Lainas P; Saloum Diop P; Holopherne D; Gonin P; Benihoud K; Ba N; Gauthier O; Franco D; Guettier C; Pariente D; Weber A; Dagher I; Huy Nguyen T
    Cell Med; 2012 Feb; 4(2):85-98. PubMed ID: 26858856
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Increasing hepatic cholesterol 7alpha-hydroxylase reduces plasma cholesterol concentrations in normocholesterolemic and hypercholesterolemic rabbits.
    Xu G; Salen G; Shefer S; Ness GC; Nguyen LB; Tint GS; Parker TS; Roberts J; Batta AK; Chen TS; Zhao Z; Kong X
    Hepatology; 1996 Oct; 24(4):882-7. PubMed ID: 8855192
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Adenovirus-mediated gene transfer of human lipoprotein lipase ameliorates the hyperlipidemias associated with apolipoprotein E and LDL receptor deficiencies in mice.
    Zsigmond E; Kobayashi K; Tzung KW; Li L; Fuke Y; Chan L
    Hum Gene Ther; 1997 Nov; 8(16):1921-33. PubMed ID: 9382958
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Retroviral vector-mediated in vivo expression of low-density-lipoprotein receptors in the Watanabe heritable hyperlipidemic rabbit.
    Dichek DA; Bratthauer GL; Beg ZH; Anderson KD; Newman KD; Zwiebel JA; Hoeg JM; Anderson WF
    Somat Cell Mol Genet; 1991 May; 17(3):287-301. PubMed ID: 1675491
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Helper-dependent adenovirus-mediated gene transfer of a secreted LDL receptor/transferrin chimeric protein reduces aortic atherosclerosis in LDL receptor-deficient mice.
    Leggiero E; Labruna G; Iaffaldano L; Lombardo B; Greco A; Fiorenza D; Gramanzini M; Montanaro D; Baldi A; Cerullo V; Sacchetti L; Pastore L
    Gene Ther; 2019 Apr; 26(3-4):121-130. PubMed ID: 30700805
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Long-term improvement of hypercholesterolemia after ex vivo gene therapy in LDLR-deficient rabbits.
    Chowdhury JR; Grossman M; Gupta S; Chowdhury NR; Baker JR; Wilson JM
    Science; 1991 Dec; 254(5039):1802-5. PubMed ID: 1722351
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Construction of minicircle DNA vectors capable of correcting familial hypercholesterolemia phenotype in a LDLR-deficient mouse model.
    Hou X; Jiao R; Guo X; Wang T; Chen P; Wang D; Chen Y; He CY; Chen ZY
    Gene Ther; 2016 Aug; 23(8-9):657-63. PubMed ID: 27092942
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 5.