BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

701 related articles for article (PubMed ID: 15094777)

  • 1. Inhibition of tumor-associated fatty acid synthase activity antagonizes estradiol- and tamoxifen-induced agonist transactivation of estrogen receptor (ER) in human endometrial adenocarcinoma cells.
    Menendez JA; Oza BP; Atlas E; Verma VA; Mehmi I; Lupu R
    Oncogene; 2004 Jun; 23(28):4945-58. PubMed ID: 15094777
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The estrogenic activity of synthetic progestins used in oral contraceptives enhances fatty acid synthase-dependent breast cancer cell proliferation and survival.
    Menendez JA; Oza BP; Colomer R; Lupu R
    Int J Oncol; 2005 Jun; 26(6):1507-15. PubMed ID: 15870863
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Novel signaling molecules implicated in tumor-associated fatty acid synthase-dependent breast cancer cell proliferation and survival: Role of exogenous dietary fatty acids, p53-p21WAF1/CIP1, ERK1/2 MAPK, p27KIP1, BRCA1, and NF-kappaB.
    Menendez JA; Mehmi I; Atlas E; Colomer R; Lupu R
    Int J Oncol; 2004 Mar; 24(3):591-608. PubMed ID: 14767544
    [TBL] [Abstract][Full Text] [Related]  

  • 4. RNA interference-mediated silencing of the p53 tumor-suppressor protein drastically increases apoptosis after inhibition of endogenous fatty acid metabolism in breast cancer cells.
    Menendez JA; Lupu R
    Int J Mol Med; 2005 Jan; 15(1):33-40. PubMed ID: 15583825
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Overexpression and hyperactivity of breast cancer-associated fatty acid synthase (oncogenic antigen-519) is insensitive to normal arachidonic fatty acid-induced suppression in lipogenic tissues but it is selectively inhibited by tumoricidal alpha-linolenic and gamma-linolenic fatty acids: a novel mechanism by which dietary fat can alter mammary tumorigenesis.
    Menendez JA; Ropero S; Mehmi I; Atlas E; Colomer R; Lupu R
    Int J Oncol; 2004 Jun; 24(6):1369-83. PubMed ID: 15138577
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Targeting fatty acid synthase in breast and endometrial cancer: An alternative to selective estrogen receptor modulators?
    Lupu R; Menendez JA
    Endocrinology; 2006 Sep; 147(9):4056-66. PubMed ID: 16809439
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Does endogenous fatty acid metabolism allow cancer cells to sense hypoxia and mediate hypoxic vasodilatation? Characterization of a novel molecular connection between fatty acid synthase (FAS) and hypoxia-inducible factor-1alpha (HIF-1alpha)-related expression of vascular endothelial growth factor (VEGF) in cancer cells overexpressing her-2/neu oncogene.
    Menendez JA; Vellon L; Oza BP; Lupu R
    J Cell Biochem; 2005 Apr; 94(5):857-63. PubMed ID: 15669079
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Resveratrol exhibits cytostatic and antiestrogenic properties with human endometrial adenocarcinoma (Ishikawa) cells.
    Bhat KP; Pezzuto JM
    Cancer Res; 2001 Aug; 61(16):6137-44. PubMed ID: 11507064
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Pharmacological inhibition of fatty acid synthase (FAS): a novel therapeutic approach for breast cancer chemoprevention through its ability to suppress Her-2/neu (erbB-2) oncogene-induced malignant transformation.
    Menendez JA; Mehmi I; Verma VA; Teng PK; Lupu R
    Mol Carcinog; 2004 Nov; 41(3):164-78. PubMed ID: 15390078
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Inhibition of fatty acid synthase-dependent neoplastic lipogenesis as the mechanism of gamma-linolenic acid-induced toxicity to tumor cells: an extension to Nwankwo's hypothesis.
    Menendez JA; Colomer R; Lupu R
    Med Hypotheses; 2005; 64(2):337-41. PubMed ID: 15607568
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Effects of the antiestrogens tamoxifen and raloxifene on the estrogen receptor transactivation machinery.
    Glaeser M; Niederacher D; Djahansouzi S; Hanstein B; Dittrich R; Beckmann MW; Fasching PA; Ackermann S
    Anticancer Res; 2006; 26(1B):735-44. PubMed ID: 16739346
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Tamoxifen induces p21WAF1 and p27KIP1 expression in estrogen receptor-negative lung cancer cells.
    Lee TH; Chuang LY; Hung WC
    Oncogene; 1999 Jul; 18(29):4269-74. PubMed ID: 10435640
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Tamoxifen regulates human telomerase reverse transcriptase (hTERT) gene expression differently in breast and endometrial cancer cells.
    Wang Z; Kyo S; Maida Y; Takakura M; Tanaka M; Yatabe N; Kanaya T; Nakamura M; Koike K; Hisamoto K; Ohmichi M; Inoue M
    Oncogene; 2002 May; 21(22):3517-24. PubMed ID: 12032853
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Idoxifene antagonizes estradiol-dependent MCF-7 breast cancer xenograft growth through sustained induction of apoptosis.
    Johnston SR; Boeddinghaus IM; Riddler S; Haynes BP; Hardcastle IR; Rowlands M; Grimshaw R; Jarman M; Dowsett M
    Cancer Res; 1999 Aug; 59(15):3646-51. PubMed ID: 10446976
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Cloning and functional characterization of PELP1/MNAR promoter.
    Mishra SK; Balasenthil S; Nguyen D; Vadlamudi RK
    Gene; 2004 Apr; 330():115-22. PubMed ID: 15087130
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Estrogen receptor alpha and beta subtype expression and transactivation capacity are differentially affected by receptor-, hsp90- and immunophilin-ligands in human breast cancer cells.
    Gougelet A; Bouclier C; Marsaud V; Maillard S; Mueller SO; Korach KS; Renoir JM
    J Steroid Biochem Mol Biol; 2005 Feb; 94(1-3):71-81. PubMed ID: 15862952
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Induction of p21WAF1 expression via Sp1-binding sites by tamoxifen in estrogen receptor-negative lung cancer cells.
    Lee TH; Chuang LY; Hung WC
    Oncogene; 2000 Aug; 19(33):3766-73. PubMed ID: 10949931
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A HOXA10 estrogen response element (ERE) is differentially regulated by 17 beta-estradiol and diethylstilbestrol (DES).
    Akbas GE; Song J; Taylor HS
    J Mol Biol; 2004 Jul; 340(5):1013-23. PubMed ID: 15236964
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Pharmacological inhibition of fatty acid synthase activity produces both cytostatic and cytotoxic effects modulated by p53.
    Li JN; Gorospe M; Chrest FJ; Kumaravel TS; Evans MK; Han WF; Pizer ES
    Cancer Res; 2001 Feb; 61(4):1493-9. PubMed ID: 11245456
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Activation of bone morphogenetic protein-6 gene transcription in MCF-7 cells by estrogen.
    Zhang M; Yan JD; Zhang L; Wang Q; Lü SJ; Zhang J; Zhu TH
    Chin Med J (Engl); 2005 Oct; 118(19):1629-36. PubMed ID: 16232348
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 36.