BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

132 related articles for article (PubMed ID: 15095015)

  • 1. Helix H1 of the prion protein is rather stable against environmental perturbations: molecular dynamics of mutation and deletion variants of PrP(90-231).
    Santini S; Derreumaux P
    Cell Mol Life Sci; 2004 Apr; 61(7-8):951-60. PubMed ID: 15095015
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Molecular dynamics simulations of human prion protein: importance of correct treatment of electrostatic interactions.
    Zuegg J; Gready JE
    Biochemistry; 1999 Oct; 38(42):13862-76. PubMed ID: 10529232
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Folding and intrinsic stability of deletion variants of PrP(121-231), the folded C-terminal domain of the prion protein.
    Eberl H; Glockshuber R
    Biophys Chem; 2002 May; 96(2-3):293-303. PubMed ID: 12034448
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Conformational transition of amyloid beta-peptide.
    Xu Y; Shen J; Luo X; Zhu W; Chen K; Ma J; Jiang H
    Proc Natl Acad Sci U S A; 2005 Apr; 102(15):5403-7. PubMed ID: 15800039
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Impact of the tail and mutations G131V and M129V on prion protein flexibility.
    Santini S; Claude JB; Audic S; Derreumaux P
    Proteins; 2003 May; 51(2):258-65. PubMed ID: 12660994
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Structural differences between allelic variants of the ovine prion protein revealed by molecular dynamics simulations.
    Bujdoso R; Burke DF; Thackray AM
    Proteins; 2005 Dec; 61(4):840-9. PubMed ID: 16252284
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Conformational polymorphism of the amyloidogenic peptide homologous to residues 113-127 of the prion protein.
    Satheeshkumar KS; Jayakumar R
    Biophys J; 2003 Jul; 85(1):473-83. PubMed ID: 12829502
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Perturbations in inter-domain associations may trigger the onset of pathogenic transformations in PrP(C): insights from atomistic simulations.
    Menon S; Sengupta N
    Mol Biosyst; 2015 May; 11(5):1443-53. PubMed ID: 25855580
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Prion protein peptides induce alpha-helix to beta-sheet conformational transitions.
    Nguyen J; Baldwin MA; Cohen FE; Prusiner SB
    Biochemistry; 1995 Apr; 34(13):4186-92. PubMed ID: 7703230
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Prion proteins with pathogenic and protective mutations show similar structure and dynamics.
    Bae SH; Legname G; Serban A; Prusiner SB; Wright PE; Dyson HJ
    Biochemistry; 2009 Sep; 48(34):8120-8. PubMed ID: 19618915
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A scrapie-like unfolding intermediate of the prion protein domain PrP(121-231) induced by acidic pH.
    Hornemann S; Glockshuber R
    Proc Natl Acad Sci U S A; 1998 May; 95(11):6010-4. PubMed ID: 9600908
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Evidence that the 127-164 region of prion proteins has two equi-energetic conformations with beta or alpha features.
    Derreumaux P
    Biophys J; 2001 Sep; 81(3):1657-65. PubMed ID: 11509378
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The key-role of tyrosine 155 in the mechanism of prion transconformation as highlighted by a study of sheep mutant peptides.
    Bertho G; Bouvier G; Hoa GH; Girault JP
    Peptides; 2008 Jul; 29(7):1073-84. PubMed ID: 18455265
    [TBL] [Abstract][Full Text] [Related]  

  • 14. beta-sheet constitution of prion proteins.
    Ji HF; Zhang HY
    Trends Biochem Sci; 2010 Mar; 35(3):129-34. PubMed ID: 20060302
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Exploring the propensities of helices in PrP(C) to form beta sheet using NMR structures and sequence alignments.
    Dima RI; Thirumalai D
    Biophys J; 2002 Sep; 83(3):1268-80. PubMed ID: 12202354
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Influence of the pathogenic mutations T188K/R/A on the structural stability and misfolding of human prion protein: insight from molecular dynamics simulations.
    Guo J; Ning L; Ren H; Liu H; Yao X
    Biochim Biophys Acta; 2012 Feb; 1820(2):116-23. PubMed ID: 22155634
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Comparative computational analysis of prion proteins reveals two fragments with unusual structural properties and a pattern of increase in hydrophobicity associated with disease-promoting mutations.
    Kuznetsov IB; Rackovsky S
    Protein Sci; 2004 Dec; 13(12):3230-44. PubMed ID: 15557265
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Kinetic intermediate in the folding of human prion protein.
    Apetri AC; Surewicz WK
    J Biol Chem; 2002 Nov; 277(47):44589-92. PubMed ID: 12356762
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Probing the N-terminal β-sheet conversion in the crystal structure of the human prion protein bound to a nanobody.
    Abskharon RN; Giachin G; Wohlkonig A; Soror SH; Pardon E; Legname G; Steyaert J
    J Am Chem Soc; 2014 Jan; 136(3):937-44. PubMed ID: 24400836
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Sheep prion protein synthetic peptide spanning helix 1 and beta-strand 2 (residues 142-166) shows beta-hairpin structure in solution.
    Kozin SA; Bertho G; Mazur AK; Rabesona H; Girault JP; Haertlé T; Takahashi M; Debey P; Hoa GH
    J Biol Chem; 2001 Dec; 276(49):46364-70. PubMed ID: 11577109
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.