116 related articles for article (PubMed ID: 15095864)
1. Probing the substrate recognition mechanism of the human MTH1 protein by nucleotide analogs.
Kamiya H; Yakushiji H; Dugué L; Tanimoto M; Pochet S; Nakabeppu Y; Harashima H
J Mol Biol; 2004 Feb; 336(4):843-50. PubMed ID: 15095864
[TBL] [Abstract][Full Text] [Related]
2. Substrate recognition by the human MTH1 protein.
Kamiya H; Dugué L; Yakushiji H; Pochet S; Nakabeppu Y; Harashima H
Nucleic Acids Res Suppl; 2002; (2):85-6. PubMed ID: 12903117
[TBL] [Abstract][Full Text] [Related]
3. Recognition of nucleotide analogs containing the 7,8-dihydro-8-oxo structure by the human MTH1 protein.
Kamiya H; Cadena-Amaro C; Dugué L; Yakushiji H; Minakawa N; Matsuda A; Pochet S; Nakabeppu Y; Harashima H
J Biochem; 2006 Dec; 140(6):843-9. PubMed ID: 17071637
[TBL] [Abstract][Full Text] [Related]
4. Human MTH1 protein hydrolyzes the oxidized ribonucleotide, 2-hydroxy-ATP.
Fujikawa K; Kamiya H; Yakushiji H; Nakabeppu Y; Kasai H
Nucleic Acids Res; 2001 Jan; 29(2):449-54. PubMed ID: 11139615
[TBL] [Abstract][Full Text] [Related]
5. A molecular basis for the selective recognition of 2-hydroxy-dATP and 8-oxo-dGTP by human MTH1.
Sakai Y; Furuichi M; Takahashi M; Mishima M; Iwai S; Shirakawa M; Nakabeppu Y
J Biol Chem; 2002 Mar; 277(10):8579-87. PubMed ID: 11756418
[TBL] [Abstract][Full Text] [Related]
6. 8-Chloro-dGTP, a hypochlorous acid-modified nucleotide, is hydrolyzed by hMTH1, the human MutT homolog.
Fujikawa K; Yakushiji H; Nakabeppu Y; Suzuki T; Masuda M; Ohshima H; Kasai H
FEBS Lett; 2002 Feb; 512(1-3):149-51. PubMed ID: 11852070
[TBL] [Abstract][Full Text] [Related]
7. The oxidized forms of dATP are substrates for the human MutT homologue, the hMTH1 protein.
Fujikawa K; Kamiya H; Yakushiji H; Fujii Y; Nakabeppu Y; Kasai H
J Biol Chem; 1999 Jun; 274(26):18201-5. PubMed ID: 10373420
[TBL] [Abstract][Full Text] [Related]
8. 2-Hydroxy-2'-deoxyadenosine 5'-triphosphate enhances A.T --> C.G mutations caused by 8-hydroxy-2'-deoxyguanosine 5'-triphosphate by suppressing its degradation upon replication in a HeLa extract.
Satou K; Kasai H; Masutani C; Hanaoka F; Harashima H; Kamiya H
Biochemistry; 2007 Jun; 46(22):6639-46. PubMed ID: 17497830
[TBL] [Abstract][Full Text] [Related]
9. MutT homologue 1 (MTH1) removes N6-methyl-dATP from the dNTP pool.
Scaletti ER; Vallin KS; Bräutigam L; Sarno A; Warpman Berglund U; Helleday T; Stenmark P; Jemth AS
J Biol Chem; 2020 Apr; 295(15):4761-4772. PubMed ID: 32144205
[TBL] [Abstract][Full Text] [Related]
10. The GT to GC single nucleotide polymorphism at the beginning of an alternative exon 2C of human MTH1 gene confers an amino terminal extension that functions as a mitochondrial targeting signal.
Sakai Y; Oda H; Yoshimura D; Furuichi M; Kang D; Iwai S; Hara T; Nakabeppu Y
J Mol Med (Berl); 2006 Aug; 84(8):660-70. PubMed ID: 16607562
[TBL] [Abstract][Full Text] [Related]
11. Structure of human MTH1, a Nudix family hydrolase that selectively degrades oxidized purine nucleoside triphosphates.
Mishima M; Sakai Y; Itoh N; Kamiya H; Furuichi M; Takahashi M; Yamagata Y; Iwai S; Nakabeppu Y; Shirakawa M
J Biol Chem; 2004 Aug; 279(32):33806-15. PubMed ID: 15133035
[TBL] [Abstract][Full Text] [Related]
12. MTH1, an oxidized purine nucleoside triphosphatase, prevents the cytotoxicity and neurotoxicity of oxidized purine nucleotides.
Nakabeppu Y; Kajitani K; Sakamoto K; Yamaguchi H; Tsuchimoto D
DNA Repair (Amst); 2006 Jul; 5(7):761-72. PubMed ID: 16621731
[TBL] [Abstract][Full Text] [Related]
13. Development of MTH1-Binding Nucleotide Analogs Based on 7,8-Dihalogenated 7-Deaza-dG Derivatives.
Shi H; Ishikawa R; Heh CH; Sasaki S; Taniguchi Y
Int J Mol Sci; 2021 Jan; 22(3):. PubMed ID: 33525366
[TBL] [Abstract][Full Text] [Related]
14. Molecular genetics and structural biology of human MutT homolog, MTH1.
Nakabeppu Y
Mutat Res; 2001 Jun; 477(1-2):59-70. PubMed ID: 11376687
[TBL] [Abstract][Full Text] [Related]
15. Protonation states of Asp residues in the human Nudix hydrolase MTH1 contribute to its broad substrate recognition.
Nakamura T; Koga-Ogawa Y; Fujimiya K; Chirifu M; Goto M; Ikemizu S; Nakabeppu Y; Yamagata Y
FEBS Lett; 2023 Jul; 597(13):1770-1778. PubMed ID: 36914375
[TBL] [Abstract][Full Text] [Related]
16. MutT homologue 1 (MTH1) catalyzes the hydrolysis of mutagenic O6-methyl-dGTP.
Jemth AS; Gustafsson R; Bräutigam L; Henriksson L; Vallin KSA; Sarno A; Almlöf I; Homan E; Rasti A; Warpman Berglund U; Stenmark P; Helleday T
Nucleic Acids Res; 2018 Nov; 46(20):10888-10904. PubMed ID: 30304478
[TBL] [Abstract][Full Text] [Related]
17. Role of tryptophan residues in the recognition of mutagenic oxidized nucleotides by human antimutator MTH1 protein.
Takahashi M; Maraboeuf F; Sakai Y; Yakushiji H; Mishima M; Shirakawa M; Iwai S; Hayakawa H; Sekiguchi M; Nakabeppu Y
J Mol Biol; 2002 May; 319(1):129-39. PubMed ID: 12051941
[TBL] [Abstract][Full Text] [Related]
18. Structural and Kinetic Studies of the Human Nudix Hydrolase MTH1 Reveal the Mechanism for Its Broad Substrate Specificity.
Waz S; Nakamura T; Hirata K; Koga-Ogawa Y; Chirifu M; Arimori T; Tamada T; Ikemizu S; Nakabeppu Y; Yamagata Y
J Biol Chem; 2017 Feb; 292(7):2785-2794. PubMed ID: 28035004
[TBL] [Abstract][Full Text] [Related]
19. An oxidized purine nucleoside triphosphatase, MTH1, suppresses cell death caused by oxidative stress.
Yoshimura D; Sakumi K; Ohno M; Sakai Y; Furuichi M; Iwai S; Nakabeppu Y
J Biol Chem; 2003 Sep; 278(39):37965-73. PubMed ID: 12857738
[TBL] [Abstract][Full Text] [Related]
20. Crystal structure of human MTH1 and the 8-oxo-dGMP product complex.
Svensson LM; Jemth AS; Desroses M; Loseva O; Helleday T; Högbom M; Stenmark P
FEBS Lett; 2011 Aug; 585(16):2617-21. PubMed ID: 21787772
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
