102 related articles for article (PubMed ID: 15102940)
21. High affinity HERG K(+) channel blockade by the antiarrhythmic agent dronedarone: resistance to mutations of the S6 residues Y652 and F656.
Ridley JM; Milnes JT; Witchel HJ; Hancox JC
Biochem Biophys Res Commun; 2004 Dec; 325(3):883-91. PubMed ID: 15541373
[TBL] [Abstract][Full Text] [Related]
22. PD-118057 contacts the pore helix of hERG1 channels to attenuate inactivation and enhance K+ conductance.
Perry M; Sachse FB; Abbruzzese J; Sanguinetti MC
Proc Natl Acad Sci U S A; 2009 Nov; 106(47):20075-80. PubMed ID: 19892732
[TBL] [Abstract][Full Text] [Related]
23. Effect of S5P alpha-helix charge mutants on inactivation of hERG K+ channels.
Clarke CE; Hill AP; Zhao J; Kondo M; Subbiah RN; Campbell TJ; Vandenberg JI
J Physiol; 2006 Jun; 573(Pt 2):291-304. PubMed ID: 16556651
[TBL] [Abstract][Full Text] [Related]
24. Blockade of HERG channels by the class III antiarrhythmic azimilide: mode of action.
Busch AE; Eigenberger B; Jurkiewicz NK; Salata JJ; Pica A; Suessbrich H; Lang F
Br J Pharmacol; 1998 Jan; 123(1):23-30. PubMed ID: 9484850
[TBL] [Abstract][Full Text] [Related]
25. Molecular determinant of high-affinity dofetilide binding to HERG1 expressed in Xenopus oocytes: involvement of S6 sites.
Lees-Miller JP; Duan Y; Teng GQ; Duff HJ
Mol Pharmacol; 2000 Feb; 57(2):367-74. PubMed ID: 10648647
[TBL] [Abstract][Full Text] [Related]
26. Hydrophobic mutations alter the movement of Mg2+ in the pore of voltage-gated potassium channels.
Harris RE; Isacoff EY
Biophys J; 1996 Jul; 71(1):209-19. PubMed ID: 8804604
[TBL] [Abstract][Full Text] [Related]
27. Molecular regions responsible for differences in activation between heag channels.
Ju M; Wray D
Biochem Biophys Res Commun; 2006 Apr; 342(4):1088-97. PubMed ID: 16513085
[TBL] [Abstract][Full Text] [Related]
28. Tuning of EAG K(+) channel inactivation: molecular determinants of amplification by mutations and a small molecule.
Garg V; Sachse FB; Sanguinetti MC
J Gen Physiol; 2012 Sep; 140(3):307-24. PubMed ID: 22930803
[TBL] [Abstract][Full Text] [Related]
29. Molecular basis of slow activation of the human ether-a-go-go related gene potassium channel.
Subbiah RN; Clarke CE; Smith DJ; Zhao J; Campbell TJ; Vandenberg JI
J Physiol; 2004 Jul; 558(Pt 2):417-31. PubMed ID: 15181157
[TBL] [Abstract][Full Text] [Related]
30. Differential effects of amino-terminal distal and proximal domains in the regulation of human erg K(+) channel gating.
Viloria CG; Barros F; Giráldez T; Gómez-Varela D; de la Peña P
Biophys J; 2000 Jul; 79(1):231-46. PubMed ID: 10866950
[TBL] [Abstract][Full Text] [Related]
31. Blockade of HERG channels expressed in Xenopus laevis oocytes by external divalent cations.
Ho WK; Kim I; Lee CO; Youm JB; Lee SH; Earm YE
Biophys J; 1999 Apr; 76(4):1959-71. PubMed ID: 10096894
[TBL] [Abstract][Full Text] [Related]
32. Molecular interaction of droperidol with human ether-a-go-go-related gene channels: prolongation of action potential duration without inducing early afterdepolarization.
Schwoerer AP; Blütner C; Brandt S; Binder S; Siebrands CC; Ehmke H; Friederich P
Anesthesiology; 2007 May; 106(5):967-76. PubMed ID: 17457128
[TBL] [Abstract][Full Text] [Related]
33. An amino acid residue whose change by mutation affects drug binding to the HERG channel.
Ishii K; Kondo K; Takahashi M; Kimura M; Endoh M
FEBS Lett; 2001 Oct; 506(3):191-5. PubMed ID: 11602243
[TBL] [Abstract][Full Text] [Related]
34. Structural basis of action for a human ether-a-go-go-related gene 1 potassium channel activator.
Perry M; Sachse FB; Sanguinetti MC
Proc Natl Acad Sci U S A; 2007 Aug; 104(34):13827-32. PubMed ID: 17693551
[TBL] [Abstract][Full Text] [Related]
35. Block of the inactivating potassium channel by clofilium and hydroxylamine depends on the sequence of the pore region.
Yool AJ
Mol Pharmacol; 1994 Nov; 46(5):970-6. PubMed ID: 7969088
[TBL] [Abstract][Full Text] [Related]
36. Physicochemical basis for binding and voltage-dependent block of hERG channels by structurally diverse drugs.
Sanguinetti MC; Chen J; Fernandez D; Kamiya K; Mitcheson J; Sanchez-Chapula JA
Novartis Found Symp; 2005; 266():159-66; discussion 166-70. PubMed ID: 16050267
[TBL] [Abstract][Full Text] [Related]
37. Molecular characterization, functional expression, and developmental profile of an ether à-go-go K+ channel in the tobacco hornworm Manduca sexta.
Keyser MR; Anson BD; Titus SA; Ganetzky B; Witten JL
J Neurobiol; 2003 Apr; 55(1):73-85. PubMed ID: 12605460
[TBL] [Abstract][Full Text] [Related]
38. The voltage dependence of hEag currents is not determined solely by membrane-spanning domains.
Lörinczi E; Napp J; Contreras-Jurado C; Pardo LA; Stühmer W
Eur Biophys J; 2009 Mar; 38(3):279-84. PubMed ID: 18379771
[TBL] [Abstract][Full Text] [Related]
39. Altered gating of HERG potassium channels by cobalt and lanthanum.
Sanchez-Chapula JA; Sanguinetti MC
Pflugers Arch; 2000 Jun; 440(2):264-74. PubMed ID: 10898527
[TBL] [Abstract][Full Text] [Related]
40. Mechanism of block of hEag1 K+ channels by imipramine and astemizole.
García-Ferreiro RE; Kerschensteiner D; Major F; Monje F; Stühmer W; Pardo LA
J Gen Physiol; 2004 Oct; 124(4):301-17. PubMed ID: 15365094
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
