BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

471 related articles for article (PubMed ID: 15104253)

  • 1. The induction of human UDP-glucuronosyltransferase 1A1 mediated through a distal enhancer module by flavonoids and xenobiotics.
    Sugatani J; Yamakawa K; Tonda E; Nishitani S; Yoshinari K; Degawa M; Abe I; Noguchi H; Miwa M
    Biochem Pharmacol; 2004 Mar; 67(5):989-1000. PubMed ID: 15104253
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Bioactive terpenoids and flavonoids from Ginkgo biloba extract induce the expression of hepatic drug-metabolizing enzymes through pregnane X receptor, constitutive androstane receptor, and aryl hydrocarbon receptor-mediated pathways.
    Li L; Stanton JD; Tolson AH; Luo Y; Wang H
    Pharm Res; 2009 Apr; 26(4):872-82. PubMed ID: 19034627
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Induction of UGT1A1 and CYP2B6 by an antimitogenic factor in HepG2 cells is mediated through suppression of cyclin-dependent kinase 2 activity: cell cycle-dependent expression.
    Sugatani J; Osabe M; Kurosawa M; Kitamura N; Ikari A; Miwa M
    Drug Metab Dispos; 2010 Jan; 38(1):177-86. PubMed ID: 19797611
    [TBL] [Abstract][Full Text] [Related]  

  • 4. A novel distal enhancer module regulated by pregnane X receptor/constitutive androstane receptor is essential for the maximal induction of CYP2B6 gene expression.
    Wang H; Faucette S; Sueyoshi T; Moore R; Ferguson S; Negishi M; LeCluyse EL
    J Biol Chem; 2003 Apr; 278(16):14146-52. PubMed ID: 12571232
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Valproic acid induces CYP3A4 and MDR1 gene expression by activation of constitutive androstane receptor and pregnane X receptor pathways.
    Cerveny L; Svecova L; Anzenbacherova E; Vrzal R; Staud F; Dvorak Z; Ulrichova J; Anzenbacher P; Pavek P
    Drug Metab Dispos; 2007 Jul; 35(7):1032-41. PubMed ID: 17392393
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Cell Cycle and Apoptosis Regulator 1, CCAR1, Regulates Enhancer-Dependent Nuclear Receptor CAR Transactivation.
    Kanno Y; Zhao S; Yamashita N; Saito N; Ujiie A; Iijima R; Kikawa N; Nemoto K; Inouye Y
    Mol Pharmacol; 2019 Jan; 95(1):120-126. PubMed ID: 30397001
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Regulation of pregnane X receptor (PXR) function and UGT1A1 gene expression by posttranslational modification of PXR protein.
    Sugatani J; Uchida T; Kurosawa M; Yamaguchi M; Yamazaki Y; Ikari A; Miwa M
    Drug Metab Dispos; 2012 Oct; 40(10):2031-40. PubMed ID: 22829544
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Differential regulation of hepatic CYP2B6 and CYP3A4 genes by constitutive androstane receptor but not pregnane X receptor.
    Faucette SR; Sueyoshi T; Smith CM; Negishi M; Lecluyse EL; Wang H
    J Pharmacol Exp Ther; 2006 Jun; 317(3):1200-9. PubMed ID: 16513849
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Polycyclic aromatic hydrocarbons stimulate human CYP3A4 promoter activity via PXR.
    Luckert C; Ehlers A; Buhrke T; Seidel A; Lampen A; Hessel S
    Toxicol Lett; 2013 Oct; 222(2):180-8. PubMed ID: 23845848
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Transcriptional regulation of human UGT1A1 gene expression through distal and proximal promoter motifs: implication of defects in the UGT1A1 gene promoter.
    Sugatani J; Mizushima K; Osabe M; Yamakawa K; Kakizaki S; Takagi H; Mori M; Ikari A; Miwa M
    Naunyn Schmiedebergs Arch Pharmacol; 2008 Jun; 377(4-6):597-605. PubMed ID: 18172616
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Transcriptional regulation of human UGT1A1 gene expression: activated glucocorticoid receptor enhances constitutive androstane receptor/pregnane X receptor-mediated UDP-glucuronosyltransferase 1A1 regulation with glucocorticoid receptor-interacting protein 1.
    Sugatani J; Nishitani S; Yamakawa K; Yoshinari K; Sueyoshi T; Negishi M; Miwa M
    Mol Pharmacol; 2005 Mar; 67(3):845-55. PubMed ID: 15557560
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The pregnane X receptor binds to response elements in a genomic context-dependent manner, and PXR activator rifampicin selectively alters the binding among target genes.
    Song X; Xie M; Zhang H; Li Y; Sachdeva K; Yan B
    Drug Metab Dispos; 2004 Jan; 32(1):35-42. PubMed ID: 14709618
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Up-regulation of CYP expression in hepatoma cells stably transfected by chimeric nuclear receptors.
    Küblbeck J; Reinisalo M; Mustonen R; Honkakoski P
    Eur J Pharm Sci; 2010 Jul; 40(4):263-72. PubMed ID: 20381613
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Glucocorticoid receptor enhancement of pregnane X receptor-mediated CYP2B6 regulation in primary human hepatocytes.
    Wang H; Faucette SR; Gilbert D; Jolley SL; Sueyoshi T; Negishi M; LeCluyse EL
    Drug Metab Dispos; 2003 May; 31(5):620-30. PubMed ID: 12695351
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Regulation of cytochrome P450 2C9 expression in primary cultures of human hepatocytes.
    Sahi J; Shord SS; Lindley C; Ferguson S; LeCluyse EL
    J Biochem Mol Toxicol; 2009; 23(1):43-58. PubMed ID: 19202563
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Differential activation of pregnane X receptor and constitutive androstane receptor by buprenorphine in primary human hepatocytes and HepG2 cells.
    Li L; Hassan HE; Tolson AH; Ferguson SS; Eddington ND; Wang H
    J Pharmacol Exp Ther; 2010 Dec; 335(3):562-71. PubMed ID: 20829393
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Differences in Gene Regulation by Dual Ligands of Nuclear Receptors Constitutive Androstane Receptor (CAR) and Pregnane X Receptor (PXR) in HepG2 Cells Stably Expressing CAR/PXR.
    Kanno Y; Tanuma N; Yazawa S; Zhao S; Inaba M; Nakamura S; Nemoto K; Inouye Y
    Drug Metab Dispos; 2016 Aug; 44(8):1158-63. PubMed ID: 27197997
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Human constitutive androstane receptor mediates induction of CYP2B6 gene expression by phenytoin.
    Wang H; Faucette S; Moore R; Sueyoshi T; Negishi M; LeCluyse E
    J Biol Chem; 2004 Jul; 279(28):29295-301. PubMed ID: 15123723
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Mechanisms of cytochrome P450 induction.
    Tompkins LM; Wallace AD
    J Biochem Mol Toxicol; 2007; 21(4):176-81. PubMed ID: 17936931
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Endosulfan induces CYP2B6 and CYP3A4 by activating the pregnane X receptor.
    Casabar RC; Das PC; Dekrey GK; Gardiner CS; Cao Y; Rose RL; Wallace AD
    Toxicol Appl Pharmacol; 2010 Jun; 245(3):335-43. PubMed ID: 20361990
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 24.