These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

182 related articles for article (PubMed ID: 15105115)

  • 1. Novel 4'-substituted stavudine analog with improved anti-human immunodeficiency virus activity and decreased cytotoxicity.
    Dutschman GE; Grill SP; Gullen EA; Haraguchi K; Takeda S; Tanaka H; Baba M; Cheng YC
    Antimicrob Agents Chemother; 2004 May; 48(5):1640-6. PubMed ID: 15105115
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Comparison of the phosphorylation of 4'-ethynyl 2',3'-dihydro-3'-deoxythymidine with that of other anti-human immunodeficiency virus thymidine analogs.
    Hsu CH; Hu R; Dutschman GE; Yang G; Krishnan P; Tanaka H; Baba M; Cheng YC
    Antimicrob Agents Chemother; 2007 May; 51(5):1687-93. PubMed ID: 17353236
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Metabolism of 2',3'-dideoxy-2',3'-didehydro-beta-L(-)-5-fluorocytidine and its activity in combination with clinically approved anti-human immunodeficiency virus beta-D(+) nucleoside analogs in vitro.
    Dutschman GE; Bridges EG; Liu SH; Gullen E; Guo X; Kukhanova M; Cheng YC
    Antimicrob Agents Chemother; 1998 Jul; 42(7):1799-804. PubMed ID: 9661024
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Intracellular metabolism and persistence of the anti-human immunodeficiency virus activity of 2',3'-didehydro-3'-deoxy-4'-ethynylthymidine, a novel thymidine analog.
    Paintsil E; Dutschman GE; Hu R; Grill SP; Lam W; Baba M; Tanaka H; Cheng YC
    Antimicrob Agents Chemother; 2007 Nov; 51(11):3870-9. PubMed ID: 17724147
    [TBL] [Abstract][Full Text] [Related]  

  • 5. 4'-Ethynylstavudine (4'-Ed4T) has potent anti-HIV-1 activity with reduced toxicity and shows a unique activity profile against drug-resistant mutants.
    Tanaka H; Haraguchi K; Kumamoto H; Baba M; Cheng YC
    Antivir Chem Chemother; 2005; 16(4):217-21. PubMed ID: 16130520
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Synthesis of a highly active new anti-HIV agent 2',3'-didehydro-3'-deoxy-4'-ethynylthymidine.
    Haraguchi K; Takeda S; Tanaka H; Nitanda T; Baba M; Dutschman GE; Cheng YC
    Bioorg Med Chem Lett; 2003 Nov; 13(21):3775-7. PubMed ID: 14552777
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Myristoylated derivatives of 2',3'-didehydro-2',3'-dideoxythymidine (stavudine) bi-functional prodrugs with potent anti-HIV-1 activity and low cytotoxicity.
    Singh RK; Miazga A; Dąbrowska A; Lipniacki A; Piasek A; Kulikowski T; Shugar D
    Antivir Chem Chemother; 2014 Dec; 23(6):231-5. PubMed ID: 23985753
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Polyfluoroaromatic stavudine (d4T) ProTides exhibit enhanced anti-HIV activity.
    Kandil S; Pannecouque C; Chapman FM; Westwell AD; McGuigan C
    Bioorg Med Chem Lett; 2019 Dec; 29(24):126721. PubMed ID: 31679972
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Metabolism and activities of 3'-azido-2',3'-dideoxythymidine and 2',3'-didehydro-2',3'-dideoxythymidine in herpesvirus thymidine kinase transduced T-lymphocytes.
    Drake RR; McMasters R; Krisa S; Hume SD; Rechtin TM; Saylors RL; Chiang Y; Govindarajan R; Munshi NC
    Antiviral Res; 1997 Aug; 35(3):177-85. PubMed ID: 9298757
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Cyclosaligenyl-2',3'-didehydro-2',3'-dideoxythymidine monophosphate: efficient intracellular delivery of d4TMP.
    Balzarini J; Aquaro S; Knispel T; Rampazzo C; Bianchi V; Perno CF; De Clercq E; Meier C
    Mol Pharmacol; 2000 Nov; 58(5):928-35. PubMed ID: 11040039
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Enhancing effects of a mono-bromo substitution at the para position of the phenyl moiety on the metabolism and anti-HIV activity of d4T-phenyl methoxyalaninyl phosphate derivatives.
    Venkatachalam TK; Tai HL; Vig R; Chen CL; Jan ST; Uckun FM
    Bioorg Med Chem Lett; 1998 Nov; 8(22):3121-6. PubMed ID: 9873688
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Relative mutagenic potencies of several nucleoside analogs, alone or in drug pairs, at the HPRT and TK loci of human TK6 lymphoblastoid cells.
    Carter MM; Torres SM; Cook DL; McCash CL; Yu M; Walker VE; Walker DM
    Environ Mol Mutagen; 2007; 48(3-4):239-47. PubMed ID: 17358029
    [TBL] [Abstract][Full Text] [Related]  

  • 13. A new approach to the synthesis of 4'-carbon-substituted nucleosides: development of a highly active anti-HIV agent 2', 3'-didehydro-3'-deoxy-4'-ethynylthymidine.
    Haraguchi K; Takeda S; Sumino M; Tanaka H; Dutschman GE; Cheng YC; Nitanda T; Baba M
    Nucleosides Nucleotides Nucleic Acids; 2005; 24(5-7):343-7. PubMed ID: 16247949
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Synthesis and biological evaluation of fatty acyl ester derivatives of 2',3'-didehydro-2',3'-dideoxythymidine.
    Agarwal HK; Loethan K; Mandal D; Doncel GF; Parang K
    Bioorg Med Chem Lett; 2011 Apr; 21(7):1917-21. PubMed ID: 21382714
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Differential patterns of intracellular metabolism of 2',3'-didehydro-2',3'-dideoxythymidine and 3'-azido-2',3'-dideoxythymidine, two potent anti-human immunodeficiency virus compounds.
    Balzarini J; Herdewijn P; De Clercq E
    J Biol Chem; 1989 Apr; 264(11):6127-33. PubMed ID: 2539371
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Mechanism of inhibition of human immunodeficiency virus type 1 reverse transcriptase by a stavudine analogue, 4'-ethynyl stavudine triphosphate.
    Yang G; Wang J; Cheng Y; Dutschman GE; Tanaka H; Baba M; Cheng YC
    Antimicrob Agents Chemother; 2008 Jun; 52(6):2035-42. PubMed ID: 18391035
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Anti-HIV antiviral activity of stavudine in a thymidine kinase-deficient cellular line.
    Turriziani O; Simeoni E; Dianzani F; Antonelli G
    Antivir Ther; 1998; 3(3):191-4. PubMed ID: 10682138
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Synthesis, and in vitro enzymatic and antiviral evaluation of d4T polyphosphate derivatives as chain terminators.
    Yang S; Pannecouque C; Herdewijn P
    Chem Biodivers; 2012 Oct; 9(10):2186-94. PubMed ID: 23081918
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Selection of a T-cell line resistant to stavudine and zidovudine by prolonged treatment with stavudine.
    Turriziani O; Scagnolari C; Bambacioni F; Bellomi F; Focher F; Gentile M; Antonelli G
    Antivir Ther; 2002 Jun; 7(2):105-11. PubMed ID: 12212922
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Retention of metabolites of 2',3'-didehydro-3'-deoxy-4'-ethynylthymidine, a novel anti-human immunodeficiency virus type 1 thymidine analog, in cells.
    Wang X; Tanaka H; Baba M; Cheng YC
    Antimicrob Agents Chemother; 2009 Aug; 53(8):3317-24. PubMed ID: 19470503
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.