164 related articles for article (PubMed ID: 15110095)
1. CYP1A2 and NAT2 genotype/phenotype relations and urinary excretion of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in a human dietary intervention study.
Moonen HJ; Moonen EJ; Maas L; Dallinga JW; Kleinjans JC; de Kok TM
Food Chem Toxicol; 2004 Jun; 42(6):869-78. PubMed ID: 15110095
[TBL] [Abstract][Full Text] [Related]
2. Urinary excretion of unmetabolized and phase II conjugates of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine and 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline in humans: relationship to cytochrome P4501A2 and N-acetyltransferase activity.
Stillwell WG; Kidd LC; Wishnok JS; Tannenbaum SR; Sinha R
Cancer Res; 1997 Aug; 57(16):3457-64. PubMed ID: 9270013
[TBL] [Abstract][Full Text] [Related]
3. Excretion of the N(2)-glucuronide conjugate of 2-hydroxyamino-1-methyl-6-phenylimidazo[4,5-b]pyridine in urine and its relationship to CYP1A2 and NAT2 activity levels in humans.
Stillwell WG; Sinha R; Tannenbaum SR
Carcinogenesis; 2002 May; 23(5):831-8. PubMed ID: 12016157
[TBL] [Abstract][Full Text] [Related]
4. Pan-fried meat containing high levels of heterocyclic aromatic amines but low levels of polycyclic aromatic hydrocarbons induces cytochrome P4501A2 activity in humans.
Sinha R; Rothman N; Brown ED; Mark SD; Hoover RN; Caporaso NE; Levander OA; Knize MG; Lang NP; Kadlubar FF
Cancer Res; 1994 Dec; 54(23):6154-9. PubMed ID: 7954461
[TBL] [Abstract][Full Text] [Related]
5. Combined effects of well-done red meat, smoking, and rapid N-acetyltransferase 2 and CYP1A2 phenotypes in increasing colorectal cancer risk.
Le Marchand L; Hankin JH; Wilkens LR; Pierce LM; Franke A; Kolonel LN; Seifried A; Custer LJ; Chang W; Lum-Jones A; Donlon T
Cancer Epidemiol Biomarkers Prev; 2001 Dec; 10(12):1259-66. PubMed ID: 11751443
[TBL] [Abstract][Full Text] [Related]
6. Urinary mutagenesis and fried red meat intake: influence of cooking temperature, phenotype, and genotype of metabolizing enzymes in a controlled feeding study.
Peters U; Sinha R; Bell DA; Rothman N; Grant DJ; Watson MA; Kulldorff M; Brooks LR; Warren SH; DeMarini DM
Environ Mol Mutagen; 2004; 43(1):53-74. PubMed ID: 14743346
[TBL] [Abstract][Full Text] [Related]
7. The CYP1A2-164A-->C polymorphism (CYP1A2*1F) is associated with the risk for colorectal adenomas in humans.
Moonen H; Engels L; Kleinjans J; Kok Td
Cancer Lett; 2005 Nov; 229(1):25-31. PubMed ID: 16157215
[TBL] [Abstract][Full Text] [Related]
8. 2-amino-1-methyl-6-phenylimidazo [4,5-b] pyridine-induced DNA adducts and genotoxicity in chinese hamster ovary (CHO) cells expressing human CYP1A2 and rapid or slow acetylator N-acetyltransferase 2.
Metry KJ; Zhao S; Neale JR; Doll MA; States JC; McGregor WG; Pierce WM; Hein DW
Mol Carcinog; 2007 Jul; 46(7):553-63. PubMed ID: 17295238
[TBL] [Abstract][Full Text] [Related]
9. The urinary metabolite profile of the dietary carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine is predictive of colon DNA adducts after a low-dose exposure in humans.
Malfatti MA; Dingley KH; Nowell-Kadlubar S; Ubick EA; Mulakken N; Nelson D; Lang NP; Felton JS; Turteltaub KW
Cancer Res; 2006 Nov; 66(21):10541-7. PubMed ID: 17079477
[TBL] [Abstract][Full Text] [Related]
10. Metabolic activation and DNA adduct detection of PhIP in dogs, rats, and humans in relation to urinary bladder and colon carcinogenesis.
Kadlubar F; Kaderlik RK; Mulder GJ; Lin D; Butler MA; Teitel CH; Minchin RF; Ilett KF; Friesen MD; Bartsch H
Princess Takamatsu Symp; 1995; 23():207-13. PubMed ID: 8844812
[TBL] [Abstract][Full Text] [Related]
11. Exposure levels and cytochrome P450 1A2 activity, but not N-acetyltransferase, glutathione S-transferase (GST) M1 and T1, influence urinary mutagen excretion in smokers.
Pavanello S; Simioli P; Lupi S; Gregorio P; Clonfero E
Cancer Epidemiol Biomarkers Prev; 2002 Oct; 11(10 Pt 1):998-1003. PubMed ID: 12376499
[TBL] [Abstract][Full Text] [Related]
12. Cytochrome P4501A2: enzyme induction and genetic control in determining 4-aminobiphenyl-hemoglobin adduct levels.
Landi MT; Zocchetti C; Bernucci I; Kadlubar FF; Tannenbaum S; Skipper P; Bartsch H; Malaveille C; Shields P; Caporaso NE; Vineis P
Cancer Epidemiol Biomarkers Prev; 1996 Sep; 5(9):693-8. PubMed ID: 8877060
[TBL] [Abstract][Full Text] [Related]
13. Intra- and interindividual variability in systemic exposure in humans to 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline and 2-amino-1-methyl- 6-phenylimidazo[4,5-b]pyridine, carcinogens present in cooked beef.
Lynch AM; Knize MG; Boobis AR; Gooderham NJ; Davies DS; Murray S
Cancer Res; 1992 Nov; 52(22):6216-23. PubMed ID: 1423264
[TBL] [Abstract][Full Text] [Related]
14. N-acetyltransferase-dependent activation of 2-hydroxyamino-1-methyl-6-phenylimidazo[4,5-b]pyridine: formation of 2-amino-1-methyl-6-(5-hydroxy)phenylimidazo [4,5-b]pyridine, a possible biomarker for the reactive dose of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine.
Frandsen H; Alexander J
Carcinogenesis; 2000 Jun; 21(6):1197-203. PubMed ID: 10837010
[TBL] [Abstract][Full Text] [Related]
15. Human cytochrome P4501A2.
Landi MT; Sinha R; Lang NP; Kadlubar FF
IARC Sci Publ; 1999; (148):173-95. PubMed ID: 10493258
[TBL] [Abstract][Full Text] [Related]
16. Analysis of within-subject variation of caffeine metabolism when used to determine cytochrome P4501A2 and N-acetyltransferase-2 activities.
McQuilkin SH; Nierenberg DW; Bresnick E
Cancer Epidemiol Biomarkers Prev; 1995 Mar; 4(2):139-46. PubMed ID: 7742721
[TBL] [Abstract][Full Text] [Related]
17. Detection of 2-amino-1-methyl-6-phenylimidazo[4,5-b]-pyridine-DNA adducts in normal breast tissues and risk of breast cancer.
Zhu J; Chang P; Bondy ML; Sahin AA; Singletary SE; Takahashi S; Shirai T; Li D
Cancer Epidemiol Biomarkers Prev; 2003 Sep; 12(9):830-7. PubMed ID: 14504191
[TBL] [Abstract][Full Text] [Related]
18. Association between dietary heterocyclic amine levels, genetic polymorphisms of NAT2, CYP1A1, and CYP1A2 and risk of colorectal cancer: a hospital-based case-control study in Japan.
Kobayashi M; Otani T; Iwasaki M; Natsukawa S; Shaura K; Koizumi Y; Kasuga Y; Sakamoto H; Yoshida T; Tsugane S
Scand J Gastroenterol; 2009; 44(8):952-9. PubMed ID: 19452301
[TBL] [Abstract][Full Text] [Related]
19. Heterocyclic amines and genotype of N-acetyltransferases as risk factors for prostate cancer.
Rovito PM; Morse PD; Spinek K; Newman N; Jones RF; Wang CY; Haas GP
Prostate Cancer Prostatic Dis; 2005; 8(1):69-74. PubMed ID: 15685255
[TBL] [Abstract][Full Text] [Related]
20. The identification of [2-(14)C]2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine metabolites in humans.
Malfatti MA; Kulp KS; Knize MG; Davis C; Massengill JP; Williams S; Nowell S; MacLeod S; Dingley KH; Turteltaub KW; Lang NP; Felton JS
Carcinogenesis; 1999 Apr; 20(4):705-13. PubMed ID: 10223203
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
