BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

175 related articles for article (PubMed ID: 15118096)

  • 1. Negative selection of semimature CD4(+)8(-)HSA+ thymocytes requires the BH3-only protein Bim but is independent of death receptor signaling.
    Villunger A; Marsden VS; Zhan Y; Erlacher M; Lew AM; Bouillet P; Berzins S; Godfrey DI; Heath WR; Strasser A
    Proc Natl Acad Sci U S A; 2004 May; 101(18):7052-7. PubMed ID: 15118096
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Regulation of Bim by TCR signals in CD4/CD8 double-positive thymocytes.
    Bunin A; Khwaja FW; Kersh GJ
    J Immunol; 2005 Aug; 175(3):1532-9. PubMed ID: 16034091
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Differential roles for Bim and Nur77 in thymocyte clonal deletion induced by ubiquitous self-antigen.
    Hu QN; Baldwin TA
    J Immunol; 2015 Mar; 194(6):2643-53. PubMed ID: 25687757
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Ligation of retinoic acid receptor alpha regulates negative selection of thymocytes by inhibiting both DNA binding of nur77 and synthesis of bim.
    Szegezdi E; Kiss I; Simon A; Blaskó B; Reichert U; Michel S; Sándor M; Fésüs L; Szondy Z
    J Immunol; 2003 Apr; 170(7):3577-84. PubMed ID: 12646620
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Proapoptotic protein Bim is differentially required during thymic clonal deletion to ubiquitous versus tissue-restricted antigens.
    Suen AY; Baldwin TA
    Proc Natl Acad Sci U S A; 2012 Jan; 109(3):893-8. PubMed ID: 22215602
    [TBL] [Abstract][Full Text] [Related]  

  • 6. BH3-only Bcl-2 family member Bim is required for apoptosis of autoreactive thymocytes.
    Bouillet P; Purton JF; Godfrey DI; Zhang LC; Coultas L; Puthalakath H; Pellegrini M; Cory S; Adams JM; Strasser A
    Nature; 2002 Feb; 415(6874):922-6. PubMed ID: 11859372
    [TBL] [Abstract][Full Text] [Related]  

  • 7. BCL-2, BCL-X(L) sequester BH3 domain-only molecules preventing BAX- and BAK-mediated mitochondrial apoptosis.
    Cheng EH; Wei MC; Weiler S; Flavell RA; Mak TW; Lindsten T; Korsmeyer SJ
    Mol Cell; 2001 Sep; 8(3):705-11. PubMed ID: 11583631
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Reduction of Runx1 transcription factor activity up-regulates Fas and Bim expression and enhances the apoptotic sensitivity of double positive thymocytes.
    Abe N; Kohu K; Ohmori H; Hayashi K; Watanabe T; Hozumi K; Sato T; Habu S; Satake M
    J Immunol; 2005 Oct; 175(7):4475-82. PubMed ID: 16177090
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Apoptosis during negative selection of autoreactive thymocytes.
    Sohn SJ; Thompson J; Winoto A
    Curr Opin Immunol; 2007 Oct; 19(5):510-5. PubMed ID: 17656079
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Helios marks strongly autoreactive CD4+ T cells in two major waves of thymic deletion distinguished by induction of PD-1 or NF-κB.
    Daley SR; Hu DY; Goodnow CC
    J Exp Med; 2013 Feb; 210(2):269-85. PubMed ID: 23337809
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Loss of Bim results in abnormal accumulation of mature CD4-CD8-CD44-CD25- thymocytes.
    Hutcheson J; Perlman H
    Immunobiology; 2007; 212(8):629-36. PubMed ID: 17869640
    [TBL] [Abstract][Full Text] [Related]  

  • 12. A novel TCR transgenic model reveals that negative selection involves an immediate, Bim-dependent pathway and a delayed, Bim-independent pathway.
    Kovalovsky D; Pezzano M; Ortiz BD; Sant'Angelo DB
    PLoS One; 2010 Jan; 5(1):e8675. PubMed ID: 20072628
    [TBL] [Abstract][Full Text] [Related]  

  • 13. CD30 overexpression enhances negative selection in the thymus and mediates programmed cell death via a Bcl-2-sensitive pathway.
    Chiarle R; Podda A; Prolla G; Podack ER; Thorbecke GJ; Inghirami G
    J Immunol; 1999 Jul; 163(1):194-205. PubMed ID: 10384116
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Programmed death-1 (PD-1):PD-ligand 1 interactions inhibit TCR-mediated positive selection of thymocytes.
    Keir ME; Latchman YE; Freeman GJ; Sharpe AH
    J Immunol; 2005 Dec; 175(11):7372-9. PubMed ID: 16301644
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The proteasome inhibitor bortezomib sensitizes cells to killing by death receptor ligand TRAIL via BH3-only proteins Bik and Bim.
    Nikrad M; Johnson T; Puthalalath H; Coultas L; Adams J; Kraft AS
    Mol Cancer Ther; 2005 Mar; 4(3):443-9. PubMed ID: 15767553
    [TBL] [Abstract][Full Text] [Related]  

  • 16. XIAP inhibition of caspase-3 preserves its association with the Apaf-1 apoptosome and prevents CD95- and Bax-induced apoptosis.
    Bratton SB; Lewis J; Butterworth M; Duckett CS; Cohen GM
    Cell Death Differ; 2002 Sep; 9(9):881-92. PubMed ID: 12181739
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Translocation of Bim to the endoplasmic reticulum (ER) mediates ER stress signaling for activation of caspase-12 during ER stress-induced apoptosis.
    Morishima N; Nakanishi K; Tsuchiya K; Shibata T; Seiwa E
    J Biol Chem; 2004 Nov; 279(48):50375-81. PubMed ID: 15452118
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The BH3-only proteins Bim and Puma cooperate to impose deletional tolerance of organ-specific antigens.
    Gray DH; Kupresanin F; Berzins SP; Herold MJ; O'Reilly LA; Bouillet P; Strasser A
    Immunity; 2012 Sep; 37(3):451-62. PubMed ID: 22960223
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Reactive oxygen species regulate quiescent T-cell apoptosis via the BH3-only proapoptotic protein BIM.
    Sade H; Sarin A
    Cell Death Differ; 2004 Apr; 11(4):416-23. PubMed ID: 14713957
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Glucose induces pancreatic islet cell apoptosis that requires the BH3-only proteins Bim and Puma and multi-BH domain protein Bax.
    McKenzie MD; Jamieson E; Jansen ES; Scott CL; Huang DC; Bouillet P; Allison J; Kay TW; Strasser A; Thomas HE
    Diabetes; 2010 Mar; 59(3):644-52. PubMed ID: 19959756
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.