BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

196 related articles for article (PubMed ID: 15120650)

  • 1. MDA-7/IL-24 is a unique cytokine--tumor suppressor in the IL-10 family.
    Chada S; Sutton RB; Ekmekcioglu S; Ellerhorst J; Mumm JB; Leitner WW; Yang HY; Sahin AA; Hunt KK; Fuson KL; Poìndexter N; Roth JA; Ramesh R; Grimm EA; Mhashilkar AM
    Int Immunopharmacol; 2004 May; 4(5):649-67. PubMed ID: 15120650
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Bystander activity of Ad-mda7: human MDA-7 protein kills melanoma cells via an IL-20 receptor-dependent but STAT3-independent mechanism.
    Chada S; Mhashilkar AM; Ramesh R; Mumm JB; Sutton RB; Bocangel D; Zheng M; Grimm EA; Ekmekcioglu S
    Mol Ther; 2004 Dec; 10(6):1085-95. PubMed ID: 15564140
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Melanoma differentiation-associated gene-7 (mda-7)/interleukin (IL)-24 induces anticancer immunity in a syngeneic murine model.
    Miyahara R; Banerjee S; Kawano K; Efferson C; Tsuda N; Miyahara Y; Ioannides CG; Chada S; Ramesh R
    Cancer Gene Ther; 2006 Aug; 13(8):753-61. PubMed ID: 16543916
    [TBL] [Abstract][Full Text] [Related]  

  • 4. mda-7/IL24 kills pancreatic cancer cells by inhibition of the Wnt/PI3K signaling pathways: identification of IL-20 receptor-mediated bystander activity against pancreatic cancer.
    Chada S; Bocangel D; Ramesh R; Grimm EA; Mumm JB; Mhashilkar AM; Zheng M
    Mol Ther; 2005 May; 11(5):724-33. PubMed ID: 15851011
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Selective induction of cell cycle arrest and apoptosis in human prostate cancer cells through adenoviral transfer of the melanoma differentiation-associated -7 (mda-7)/interleukin-24 (IL-24) gene.
    Saito Y; Miyahara R; Gopalan B; Litvak A; Inoue S; Shanker M; Branch CD; Mhashilkar AM; Roth JA; Chada S; Ramesh R
    Cancer Gene Ther; 2005 Mar; 12(3):238-47. PubMed ID: 15578066
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Activation of the Fas-FasL signaling pathway by MDA-7/IL-24 kills human ovarian cancer cells.
    Gopalan B; Litvak A; Sharma S; Mhashilkar AM; Chada S; Ramesh R
    Cancer Res; 2005 Apr; 65(8):3017-24. PubMed ID: 15833826
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Unique aspects of mda-7/IL-24 antitumor bystander activity: establishing a role for secretion of MDA-7/IL-24 protein by normal cells.
    Su Z; Emdad L; Sauane M; Lebedeva IV; Sarkar D; Gupta P; James CD; Randolph A; Valerie K; Walter MR; Dent P; Fisher PB
    Oncogene; 2005 Nov; 24(51):7552-66. PubMed ID: 16044151
    [TBL] [Abstract][Full Text] [Related]  

  • 8. mda-7/IL-24, novel anticancer cytokine: focus on bystander antitumor, radiosensitization and antiangiogenic properties and overview of the phase I clinical experience (Review).
    Lebedeva IV; Emdad L; Su ZZ; Gupta P; Sauane M; Sarkar D; Staudt MR; Liu SJ; Taher MM; Xiao R; Barral P; Lee SG; Wang D; Vozhilla N; Park ES; Chatman L; Boukerche H; Ramesh R; Inoue S; Chada S; Li R; De Pass AL; Mahasreshti PJ; Dmitriev IP; Curiel DT; Yacoub A; Grant S; Dent P; Senzer N; Nemunaitis JJ; Fisher PB
    Int J Oncol; 2007 Nov; 31(5):985-1007. PubMed ID: 17912425
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Cytokine and tumor cell apoptosis inducing activity of mda-7/IL-24.
    Gopalkrishnan RV; Sauane M; Fisher PB
    Int Immunopharmacol; 2004 May; 4(5):635-47. PubMed ID: 15120649
    [TBL] [Abstract][Full Text] [Related]  

  • 10. MDA-7/IL-24, a novel tumor suppressor/cytokine is ubiquitinated and regulated by the ubiquitin-proteasome system, and inhibition of MDA-7/IL-24 degradation enhances the antitumor activity.
    Gopalan B; Shanker M; Scott A; Branch CD; Chada S; Ramesh R
    Cancer Gene Ther; 2008 Jan; 15(1):1-8. PubMed ID: 17828282
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Genomic structure, chromosomal localization and expression profile of a novel melanoma differentiation associated (mda-7) gene with cancer specific growth suppressing and apoptosis inducing properties.
    Huang EY; Madireddi MT; Gopalkrishnan RV; Leszczyniecka M; Su Z; Lebedeva IV; Kang D; Jiang H; Lin JJ; Alexandre D; Chen Y; Vozhilla N; Mei MX; Christiansen KA; Sivo F; Goldstein NI; Mhashilkar AB; Chada S; Huberman E; Pestka S; Fisher PB
    Oncogene; 2001 Oct; 20(48):7051-63. PubMed ID: 11704829
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Bcl-2 and Bcl-x(L) differentially protect human prostate cancer cells from induction of apoptosis by melanoma differentiation associated gene-7, mda-7/IL-24.
    Lebedeva IV; Sarkar D; Su ZZ; Kitada S; Dent P; Stein CA; Reed JC; Fisher PB
    Oncogene; 2003 Nov; 22(54):8758-73. PubMed ID: 14647471
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Intratumoral injection of INGN 241, a nonreplicating adenovector expressing the melanoma-differentiation associated gene-7 (mda-7/IL24): biologic outcome in advanced cancer patients.
    Tong AW; Nemunaitis J; Su D; Zhang Y; Cunningham C; Senzer N; Netto G; Rich D; Mhashilkar A; Parker K; Coffee K; Ramesh R; Ekmekcioglu S; Grimm EA; van Wart Hood J; Merritt J; Chada S
    Mol Ther; 2005 Jan; 11(1):160-72. PubMed ID: 15585417
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Melanoma differentiation-associated gene-7 protein physically associates with the double-stranded RNA-activated protein kinase PKR.
    Pataer A; Vorburger SA; Chada S; Balachandran S; Barber GN; Roth JA; Hunt KK; Swisher SG
    Mol Ther; 2005 May; 11(5):717-23. PubMed ID: 15851010
    [TBL] [Abstract][Full Text] [Related]  

  • 15. mda-7 (IL-24): signaling and functional roles.
    Sarkar D; Su ZZ; Lebedeva IV; Sauane M; Gopalkrishnan RV; Dent P; Fisher PB
    Biotechniques; 2002 Oct; Suppl():30-9. PubMed ID: 12395925
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Induction of reactive oxygen species renders mutant and wild-type K-ras pancreatic carcinoma cells susceptible to Ad.mda-7-induced apoptosis.
    Lebedeva IV; Su ZZ; Sarkar D; Gopalkrishnan RV; Waxman S; Yacoub A; Dent P; Fisher PB
    Oncogene; 2005 Jan; 24(4):585-96. PubMed ID: 15580305
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Mechanistic aspects of mda-7/IL-24 cancer cell selectivity analysed via a bacterial fusion protein.
    Sauane M; Gopalkrishnan RV; Choo HT; Gupta P; Lebedeva IV; Yacoub A; Dent P; Fisher PB
    Oncogene; 2004 Oct; 23(46):7679-90. PubMed ID: 15334067
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Cytokine induction of interleukin-24 in human peripheral blood mononuclear cells.
    Poindexter NJ; Walch ET; Chada S; Grimm EA
    J Leukoc Biol; 2005 Sep; 78(3):745-52. PubMed ID: 16000394
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Melanoma differentiation associated gene-7, mda-7/interleukin-24, induces apoptosis in prostate cancer cells by promoting mitochondrial dysfunction and inducing reactive oxygen species.
    Lebedeva IV; Su ZZ; Sarkar D; Kitada S; Dent P; Waxman S; Reed JC; Fisher PB
    Cancer Res; 2003 Dec; 63(23):8138-44. PubMed ID: 14678967
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Ionizing radiation enhances therapeutic activity of mda-7/IL-24: overcoming radiation- and mda-7/IL-24-resistance in prostate cancer cells overexpressing the antiapoptotic proteins bcl-xL or bcl-2.
    Su ZZ; Lebedeva IV; Sarkar D; Emdad L; Gupta P; Kitada S; Dent P; Reed JC; Fisher PB
    Oncogene; 2006 Apr; 25(16):2339-48. PubMed ID: 16331261
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.