1111 related articles for article (PubMed ID: 15122348)
1. Oxygen sensing by HIF hydroxylases.
Schofield CJ; Ratcliffe PJ
Nat Rev Mol Cell Biol; 2004 May; 5(5):343-54. PubMed ID: 15122348
[No Abstract] [Full Text] [Related]
2. Catalytic properties of the asparaginyl hydroxylase (FIH) in the oxygen sensing pathway are distinct from those of its prolyl 4-hydroxylases.
Koivunen P; Hirsilä M; Günzler V; Kivirikko KI; Myllyharju J
J Biol Chem; 2004 Mar; 279(11):9899-904. PubMed ID: 14701857
[TBL] [Abstract][Full Text] [Related]
3. HIF hydroxylation and cellular oxygen sensing.
Metzen E; Ratcliffe PJ
Biol Chem; 2004; 385(3-4):223-30. PubMed ID: 15134335
[TBL] [Abstract][Full Text] [Related]
4. Hypoxia, hypoxia-inducible factors (HIF), HIF hydroxylases and oxygen sensing.
Webb JD; Coleman ML; Pugh CW
Cell Mol Life Sci; 2009 Nov; 66(22):3539-54. PubMed ID: 19756382
[TBL] [Abstract][Full Text] [Related]
5. Intracellular localisation of human HIF-1 alpha hydroxylases: implications for oxygen sensing.
Metzen E; Berchner-Pfannschmidt U; Stengel P; Marxsen JH; Stolze I; Klinger M; Huang WQ; Wotzlaw C; Hellwig-Bürgel T; Jelkmann W; Acker H; Fandrey J
J Cell Sci; 2003 Apr; 116(Pt 7):1319-26. PubMed ID: 12615973
[TBL] [Abstract][Full Text] [Related]
6. Hypoxia-induced gene expression occurs solely through the action of hypoxia-inducible factor 1alpha (HIF-1alpha): role of cytoplasmic trapping of HIF-2alpha.
Park SK; Dadak AM; Haase VH; Fontana L; Giaccia AJ; Johnson RS
Mol Cell Biol; 2003 Jul; 23(14):4959-71. PubMed ID: 12832481
[TBL] [Abstract][Full Text] [Related]
7. Regulating cellular oxygen sensing by hydroxylation.
Fandrey J; Gorr TA; Gassmann M
Cardiovasc Res; 2006 Sep; 71(4):642-51. PubMed ID: 16780822
[TBL] [Abstract][Full Text] [Related]
8. Hypoxia-inducible factor (HIF) asparagine hydroxylase is identical to factor inhibiting HIF (FIH) and is related to the cupin structural family.
Hewitson KS; McNeill LA; Riordan MV; Tian YM; Bullock AN; Welford RW; Elkins JM; Oldham NJ; Bhattacharya S; Gleadle JM; Ratcliffe PJ; Pugh CW; Schofield CJ
J Biol Chem; 2002 Jul; 277(29):26351-5. PubMed ID: 12042299
[TBL] [Abstract][Full Text] [Related]
9. HIF prolyl and asparaginyl hydroxylases in the biological response to intracellular O(2) levels.
Masson N; Ratcliffe PJ
J Cell Sci; 2003 Aug; 116(Pt 15):3041-9. PubMed ID: 12829734
[TBL] [Abstract][Full Text] [Related]
10. Differential sensitivity of hypoxia inducible factor hydroxylation sites to hypoxia and hydroxylase inhibitors.
Tian YM; Yeoh KK; Lee MK; Eriksson T; Kessler BM; Kramer HB; Edelmann MJ; Willam C; Pugh CW; Schofield CJ; Ratcliffe PJ
J Biol Chem; 2011 Apr; 286(15):13041-51. PubMed ID: 21335549
[TBL] [Abstract][Full Text] [Related]
11. Hypoxia-inducible factor-1 (HIF-1) promotes its degradation by induction of HIF-alpha-prolyl-4-hydroxylases.
Marxsen JH; Stengel P; Doege K; Heikkinen P; Jokilehto T; Wagner T; Jelkmann W; Jaakkola P; Metzen E
Biochem J; 2004 Aug; 381(Pt 3):761-7. PubMed ID: 15104534
[TBL] [Abstract][Full Text] [Related]
12. Human AlkB homologue 5 is a nuclear 2-oxoglutarate dependent oxygenase and a direct target of hypoxia-inducible factor 1α (HIF-1α).
Thalhammer A; Bencokova Z; Poole R; Loenarz C; Adam J; O'Flaherty L; Schödel J; Mole D; Giaslakiotis K; Schofield CJ; Hammond EM; Ratcliffe PJ; Pollard PJ
PLoS One; 2011 Jan; 6(1):e16210. PubMed ID: 21264265
[TBL] [Abstract][Full Text] [Related]
13. The role of the hypoxia-inducible factor in tumor metabolism growth and invasion.
Brahimi-Horn C; Pouysségur J
Bull Cancer; 2006 Aug; 93(8):E73-80. PubMed ID: 16935775
[TBL] [Abstract][Full Text] [Related]
14. [Cellular and tissue hypoxia--role of the von Hippel Lindau gene and hypoxia-inducible factor-1].
Sýkora V; Necas E
Cas Lek Cesk; 2003; 142(10):595-8. PubMed ID: 14635422
[TBL] [Abstract][Full Text] [Related]
15. FIH-1 is an asparaginyl hydroxylase enzyme that regulates the transcriptional activity of hypoxia-inducible factor.
Lando D; Peet DJ; Gorman JJ; Whelan DA; Whitelaw ML; Bruick RK
Genes Dev; 2002 Jun; 16(12):1466-71. PubMed ID: 12080085
[TBL] [Abstract][Full Text] [Related]
16. Reactivating HIF prolyl hydroxylases under hypoxia results in metabolic catastrophe and cell death.
Tennant DA; Frezza C; MacKenzie ED; Nguyen QD; Zheng L; Selak MA; Roberts DL; Dive C; Watson DG; Aboagye EO; Gottlieb E
Oncogene; 2009 Nov; 28(45):4009-21. PubMed ID: 19718054
[TBL] [Abstract][Full Text] [Related]
17. Genetic analysis of the role of the asparaginyl hydroxylase factor inhibiting hypoxia-inducible factor (FIH) in regulating hypoxia-inducible factor (HIF) transcriptional target genes [corrected].
Stolze IP; Tian YM; Appelhoff RJ; Turley H; Wykoff CC; Gleadle JM; Ratcliffe PJ
J Biol Chem; 2004 Oct; 279(41):42719-25. PubMed ID: 15302861
[TBL] [Abstract][Full Text] [Related]
18. OS-9 interacts with hypoxia-inducible factor 1alpha and prolyl hydroxylases to promote oxygen-dependent degradation of HIF-1alpha.
Baek JH; Mahon PC; Oh J; Kelly B; Krishnamachary B; Pearson M; Chan DA; Giaccia AJ; Semenza GL
Mol Cell; 2005 Feb; 17(4):503-12. PubMed ID: 15721254
[TBL] [Abstract][Full Text] [Related]
19. Investigating the dependence of the hypoxia-inducible factor hydroxylases (factor inhibiting HIF and prolyl hydroxylase domain 2) on ascorbate and other reducing agents.
Flashman E; Davies SL; Yeoh KK; Schofield CJ
Biochem J; 2010 Mar; 427(1):135-42. PubMed ID: 20055761
[TBL] [Abstract][Full Text] [Related]
20. HIF-1: the knowns and unknowns of hypoxia sensing.
Zagórska A; Dulak J
Acta Biochim Pol; 2004; 51(3):563-85. PubMed ID: 15448722
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]