These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
24. Structural basis for the anticoagulant activity of the thrombin-thrombomodulin complex. Fuentes-Prior P; Iwanaga Y; Huber R; Pagila R; Rumennik G; Seto M; Morser J; Light DR; Bode W Nature; 2000 Mar; 404(6777):518-25. PubMed ID: 10761923 [TBL] [Abstract][Full Text] [Related]
25. New insights into the regulation of the blood clotting cascade derived from the X-ray crystal structure of bovine meizothrombin des F1 in complex with PPACK. Martin PD; Malkowski MG; Box J; Esmon CT; Edwards BF Structure; 1997 Dec; 5(12):1681-93. PubMed ID: 9438869 [TBL] [Abstract][Full Text] [Related]
26. Thermodynamic compensation upon binding to exosite 1 and the active site of thrombin. Treuheit NA; Beach MA; Komives EA Biochemistry; 2011 May; 50(21):4590-6. PubMed ID: 21526769 [TBL] [Abstract][Full Text] [Related]
27. NMR reveals a dynamic allosteric pathway in thrombin. Handley LD; Fuglestad B; Stearns K; Tonelli M; Fenwick RB; Markwick PR; Komives EA Sci Rep; 2017 Jan; 7():39575. PubMed ID: 28059082 [TBL] [Abstract][Full Text] [Related]
28. Biophysical investigation of GpIbalpha binding to thrombin anion binding exosite II. Sabo TM; Maurer MC Biochemistry; 2009 Aug; 48(30):7110-22. PubMed ID: 19591434 [TBL] [Abstract][Full Text] [Related]
29. Identification of protein-protein interfaces by decreased amide proton solvent accessibility. Mandell JG; Falick AM; Komives EA Proc Natl Acad Sci U S A; 1998 Dec; 95(25):14705-10. PubMed ID: 9843953 [TBL] [Abstract][Full Text] [Related]
30. Role of the thrombin insertion loop 144-155. Study of thrombin mutations W148G, K154E and a thrombin-based synthetic peptide. Bouton MC; Plantier JL; Dembak M; Guillin MC; Rabiet MJ; Jandrot-Perrus M Eur J Biochem; 1995 Apr; 229(2):526-32. PubMed ID: 7744076 [TBL] [Abstract][Full Text] [Related]
31. A novel serine protease inhibition motif involving a multi-centered short hydrogen bonding network at the active site. Katz BA; Elrod K; Luong C; Rice MJ; Mackman RL; Sprengeler PA; Spencer J; Hataye J; Janc J; Link J; Litvak J; Rai R; Rice K; Sideris S; Verner E; Young W J Mol Biol; 2001 Apr; 307(5):1451-86. PubMed ID: 11292354 [TBL] [Abstract][Full Text] [Related]
32. Crystal structure of thrombin-ecotin reveals conformational changes and extended interactions. Wang SX; Esmon CT; Fletterick RJ Biochemistry; 2001 Aug; 40(34):10038-46. PubMed ID: 11513582 [TBL] [Abstract][Full Text] [Related]
33. Crystal structure of the complex of human alpha-thrombin and nonhydrolyzable bifunctional inhibitors, hirutonin-2 and hirutonin-6. Zdanov A; Wu S; DiMaio J; Konishi Y; Li Y; Wu X; Edwards BF; Martin PD; Cygler M Proteins; 1993 Nov; 17(3):252-65. PubMed ID: 8272424 [TBL] [Abstract][Full Text] [Related]
35. Crystallographic determination of the structures of human alpha-thrombin complexed with BMS-186282 and BMS-189090. Malley MF; Tabernero L; Chang CY; Ohringer SL; Roberts DG; Das J; Sack JS Protein Sci; 1996 Feb; 5(2):221-8. PubMed ID: 8745399 [TBL] [Abstract][Full Text] [Related]
36. Crystal structures of murine thrombin in complex with the extracellular fragments of murine protease-activated receptors PAR3 and PAR4. Bah A; Chen Z; Bush-Pelc LA; Mathews FS; Di Cera E Proc Natl Acad Sci U S A; 2007 Jul; 104(28):11603-8. PubMed ID: 17606903 [TBL] [Abstract][Full Text] [Related]
37. Structural basis of thrombin-mediated factor V activation: the Glu666-Glu672 sequence is critical for processing at the heavy chain-B domain junction. Corral-Rodríguez MÁ; Bock PE; Hernández-Carvajal E; Gutiérrez-Gallego R; Fuentes-Prior P Blood; 2011 Jun; 117(26):7164-73. PubMed ID: 21555742 [TBL] [Abstract][Full Text] [Related]
38. Crystallographic structures of thrombin complexed with thrombin receptor peptides: existence of expected and novel binding modes. Mathews II; Padmanabhan KP; Ganesh V; Tulinsky A; Ishii M; Chen J; Turck CW; Coughlin SR; Fenton JW Biochemistry; 1994 Mar; 33(11):3266-79. PubMed ID: 8136362 [TBL] [Abstract][Full Text] [Related]
39. Designing allosteric regulators of thrombin. Exosite 2 features multiple subsites that can be targeted by sulfated small molecules for inducing inhibition. Sidhu PS; Abdel Aziz MH; Sarkar A; Mehta AY; Zhou Q; Desai UR J Med Chem; 2013 Jun; 56(12):5059-70. PubMed ID: 23718540 [TBL] [Abstract][Full Text] [Related]
40. Evidence that catalytically-inactivated thrombin forms non-covalently linked dimers that bridge between fibrin/fibrinogen fibers and enhance fibrin polymerization. Mosesson MW; Hernandez I; Siebenlist KR Biophys Chem; 2004 Jul; 110(1-2):93-100. PubMed ID: 15223147 [TBL] [Abstract][Full Text] [Related] [Previous] [Next] [New Search]