These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

129 related articles for article (PubMed ID: 15123685)

  • 1. Conditional expression of 15-lipoxygenase-1 inhibits the selenoenzyme thioredoxin reductase: modulation of selenoproteins by lipoxygenase enzymes.
    Yu MK; Moos PJ; Cassidy P; Wade M; Fitzpatrick FA
    J Biol Chem; 2004 Jul; 279(27):28028-35. PubMed ID: 15123685
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Electrophilic prostaglandins and lipid aldehydes repress redox-sensitive transcription factors p53 and hypoxia-inducible factor by impairing the selenoprotein thioredoxin reductase.
    Moos PJ; Edes K; Cassidy P; Massuda E; Fitzpatrick FA
    J Biol Chem; 2003 Jan; 278(2):745-50. PubMed ID: 12424231
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Selenium metabolism, selenoproteins and mechanisms of cancer prevention: complexities with thioredoxin reductase.
    Ganther HE
    Carcinogenesis; 1999 Sep; 20(9):1657-66. PubMed ID: 10469608
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Motexafin gadolinium, a tumor-selective drug targeting thioredoxin reductase and ribonucleotide reductase.
    Hashemy SI; Ungerstedt JS; Zahedi Avval F; Holmgren A
    J Biol Chem; 2006 Apr; 281(16):10691-7. PubMed ID: 16481328
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Mechanisms controlling cell cycle arrest and induction of apoptosis after 12-lipoxygenase inhibition in prostate cancer cells.
    Pidgeon GP; Kandouz M; Meram A; Honn KV
    Cancer Res; 2002 May; 62(9):2721-7. PubMed ID: 11980674
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Inhibition of thioredoxin and thioredoxin reductase by 4-hydroxy-2-nonenal in vitro and in vivo.
    Fang J; Holmgren A
    J Am Chem Soc; 2006 Feb; 128(6):1879-85. PubMed ID: 16464088
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Thioredoxin reductase reduces lipid hydroperoxides and spares alpha-tocopherol.
    May JM; Morrow JD; Burk RF
    Biochem Biophys Res Commun; 2002 Mar; 292(1):45-9. PubMed ID: 11890669
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Inhibition of cellular thioredoxin reductase by diaziquone and doxorubicin. Relationship to the inhibition of cell proliferation and decreased ribonucleotide reductase activity.
    Mau BL; Powis G
    Biochem Pharmacol; 1992 Apr; 43(7):1621-7. PubMed ID: 1567483
    [TBL] [Abstract][Full Text] [Related]  

  • 9. A diterpenoid derivate compound targets selenocysteine of thioredoxin reductases and induces Bax/Bak-independent apoptosis.
    Liu J; Mu C; Yue W; Li J; Ma B; Zhao L; Liu L; Chen Q; Yan C; Liu H; Hao X; Zhu Y
    Free Radic Biol Med; 2013 Oct; 63():485-94. PubMed ID: 23732520
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Loss of activity of the selenoenzyme thioredoxin reductase causes induction of hepatic heme oxygenase-1.
    Mostert V; Hill KE; Burk RF
    FEBS Lett; 2003 Apr; 541(1-3):85-8. PubMed ID: 12706824
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A thioredoxin reductase inhibitor induces growth inhibition and apoptosis in five cultured human carcinoma cell lines.
    Zhao F; Yan J; Deng S; Lan L; He F; Kuang B; Zeng H
    Cancer Lett; 2006 May; 236(1):46-53. PubMed ID: 15982805
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Methylseleninate is a substrate rather than an inhibitor of mammalian thioredoxin reductase. Implications for the antitumor effects of selenium.
    Gromer S; Gross JH
    J Biol Chem; 2002 Mar; 277(12):9701-6. PubMed ID: 11782468
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Selenite and selenate inhibit human lymphocyte growth via different mechanisms.
    Spyrou G; Björnstedt M; Skog S; Holmgren A
    Cancer Res; 1996 Oct; 56(19):4407-12. PubMed ID: 8813134
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The mechanism of apoptosis induced by a novel thioredoxin reductase inhibitor in A549 cells: possible involvement of nuclear factor-kappaB-dependent pathway.
    Lan L; Zhao F; Wang Y; Zeng H
    Eur J Pharmacol; 2007 Jan; 555(2-3):83-92. PubMed ID: 17116300
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Thioredoxin reductase as a potential molecular target for anticancer agents that induce oxidative stress.
    Smart DK; Ortiz KL; Mattson D; Bradbury CM; Bisht KS; Sieck LK; Brechbiel MW; Gius D
    Cancer Res; 2004 Sep; 64(18):6716-24. PubMed ID: 15374989
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The mechanism of action of the nitrosourea anti-tumor drugs on thioredoxin reductase, glutathione reductase and ribonucleotide reductase.
    Schallreuter KU; Gleason FK; Wood JM
    Biochim Biophys Acta; 1990 Aug; 1054(1):14-20. PubMed ID: 2200526
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Suppression of human prostate cancer cell growth by ciprofloxacin is associated with cell cycle arrest and apoptosis.
    Aranha O; Grignon R; Fernandes N; McDonnell TJ; Wood DP; Sarkar FH
    Int J Oncol; 2003 Apr; 22(4):787-94. PubMed ID: 12632069
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Mutational studies confirm the catalytic triad in the human selenoenzyme thioredoxin reductase predicted by molecular modeling.
    Gromer S; Wessjohann LA; Eubel J; Brandt W
    Chembiochem; 2006 Nov; 7(11):1649-52. PubMed ID: 16977661
    [No Abstract]   [Full Text] [Related]  

  • 19. Human placenta thioredoxin reductase. Isolation of the selenoenzyme, steady state kinetics, and inhibition by therapeutic gold compounds.
    Gromer S; Arscott LD; Williams CH; Schirmer RH; Becker K
    J Biol Chem; 1998 Aug; 273(32):20096-101. PubMed ID: 9685351
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Thioredoxin reductase activity is decreased by selenium deficiency.
    Hill KE; McCollum GW; Boeglin ME; Burk RF
    Biochem Biophys Res Commun; 1997 May; 234(2):293-5. PubMed ID: 9177261
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.