99 related articles for article (PubMed ID: 15130534)
1. In vivo examination of hydroxyurea and the novel ribonucleotide reductase inhibitors trimidox and didox in combination with the reverse transcriptase inhibitor abacavir: suppression of retrovirus-induced immunodeficiency disease.
Sumpter LR; Inayat MS; Yost EE; Duvall W; Hagan E; Mayhew CN; Elford HL; Gallicchio VS
Antiviral Res; 2004 Jun; 62(3):111-20. PubMed ID: 15130534
[TBL] [Abstract][Full Text] [Related]
2. Suppression of retrovirus-induced immunodeficiency disease (murine AIDS) by trimidox and didox: novel ribonucleotide reductase inhibitors with less bone marrow toxicity than hydroxyurea.
Mayhew CN; Mampuru LJ; Chendil D; Ahmed MM; Phillips JD; Greenberg RN; Elford HL; Gallicchio VS
Antiviral Res; 2002 Nov; 56(2):167-81. PubMed ID: 12367722
[TBL] [Abstract][Full Text] [Related]
3. Combination of inhibitors of lymphocyte activation (hydroxyurea, trimidox, and didox) and reverse transcriptase (didanosine) suppresses development of murine retrovirus-induced lymphoproliferative disease.
Mayhew CN; Sumpter R; Inayat M; Cibull M; Phillips JD; Elford HL; Gallicchio VS
Antiviral Res; 2005 Jan; 65(1):13-22. PubMed ID: 15652967
[TBL] [Abstract][Full Text] [Related]
4. Effective use of ribonucleotide reductase inhibitors (Didox and Trimidox) alone or in combination with didanosine (ddI) to suppress disease progression and increase survival in murine acquired immunodeficiency syndrome (MAIDS).
Mayhew C; Oakley O; Piper J; Hughes NK; Phillips J; Birch NJ; Elford HL; Gallicchio VS
Cell Mol Biol (Noisy-le-grand); 1997 Nov; 43(7):1019-29. PubMed ID: 9449534
[TBL] [Abstract][Full Text] [Related]
5. In vivo and in vitro comparison of the short-term hematopoietic toxicity between hydroxyurea and trimidox or didox, novel ribonucleotide reductase inhibitors with potential anti-HIV-1 activity.
Mayhew CN; Phillips JD; Greenberg RN; Birch NJ; Elford HL; Gallicchio VS
Stem Cells; 1999; 17(6):345-56. PubMed ID: 10606163
[TBL] [Abstract][Full Text] [Related]
6. Short-term treatment with novel ribonucleotide reductase inhibitors Trimidox and Didox reverses late-stage murine retrovirus-induced lymphoproliferative disease with less bone marrow toxicity than hydroxyurea.
Mayhew CN; Phillips JD; Cibull ML; Elford HL; Gallicchio VS
Antivir Chem Chemother; 2002 Sep; 13(5):305-14. PubMed ID: 12630679
[TBL] [Abstract][Full Text] [Related]
7. Beyond hydroxyurea.
Smart T
GMHC Treat Issues; 1995 Sep; 9(9):5. PubMed ID: 11362909
[TBL] [Abstract][Full Text] [Related]
8. DNA-protective activity of new ribonucleotide reductase inhibitors.
Rauko P; Romanova D; Miadokova E; Macakova K; Novotny L; Elford HL; Szekeres T
Anticancer Res; 1997; 17(5A):3437-40. PubMed ID: 9413183
[TBL] [Abstract][Full Text] [Related]
9. Ribonucleotide reductase inhibitors hydroxyurea, didox, and trimidox inhibit human cytomegalovirus replication in vitro and synergize with ganciclovir.
Bhave S; Elford H; McVoy MA
Antiviral Res; 2013 Oct; 100(1):151-8. PubMed ID: 23933116
[TBL] [Abstract][Full Text] [Related]
10. Enhancement of hemoglobin and F-cell production by targeting growth inhibition and differentiation of K562 cells with ribonucleotide reductase inhibitors (didox and trimidox) in combination with streptozotocin.
Iyamu WE; Adunyah SE; Fasold H; Horiuchi K; Elford HL; Asakura T; Turner EA
Am J Hematol; 2000 Apr; 63(4):176-83. PubMed ID: 10706760
[TBL] [Abstract][Full Text] [Related]
11. Combined effects of temozolomide and the ribonucleotide reductase inhibitors didox and trimidox in malignant brain tumor cells.
Figul M; Söling A; Dong HJ; Chou TC; Rainov NG
Cancer Chemother Pharmacol; 2003 Jul; 52(1):41-6. PubMed ID: 12690517
[TBL] [Abstract][Full Text] [Related]
12. The efficacy of the ribonucleotide reductase inhibitor Didox in preclinical models of AML.
Cook GJ; Caudell DL; Elford HL; Pardee TS
PLoS One; 2014; 9(11):e112619. PubMed ID: 25402485
[TBL] [Abstract][Full Text] [Related]
13. Ribavirin potentiates the efficacy and toxicity of 2',3'- dideoxyinosine in the murine acquired immunodeficiency syndrome model.
Harvie P; Omar RF; Dusserre N; Lansac N; Désormeaux A; Gourde P; Simard M; Tremblay M; Beauchamp D; Bergeron MG
J Pharmacol Exp Ther; 1996 Nov; 279(2):1009-17. PubMed ID: 8930211
[TBL] [Abstract][Full Text] [Related]
14. Biochemical and antitumor activity of trimidox, a new inhibitor of ribonucleotide reductase.
Szekeres T; Gharehbaghi K; Fritzer M; Woody M; Srivastava A; van't Riet B; Jayaram HN; Elford HL
Cancer Chemother Pharmacol; 1994; 34(1):63-6. PubMed ID: 8174204
[TBL] [Abstract][Full Text] [Related]
15. Hydroxyurea and trimidox enhance the radiation effect in human pancreatic adenocarcinoma cells.
Leyden D; Ahmed N; Hassan HT
Anticancer Res; 2000; 20(1A):133-8. PubMed ID: 10769645
[TBL] [Abstract][Full Text] [Related]
16. The enzyme ribonucleotide reductase: target for antitumor and anti-HIV therapy.
Szekeres T; Fritzer-Szekeres M; Elford HL
Crit Rev Clin Lab Sci; 1997; 34(6):503-28. PubMed ID: 9439883
[TBL] [Abstract][Full Text] [Related]
17. Didox, a ribonucleotide reductase inhibitor, induces apoptosis and inhibits DNA repair in multiple myeloma cells.
Raje N; Kumar S; Hideshima T; Ishitsuka K; Yasui H; Chhetri S; Vallet S; Vonescu E; Shiraishi N; Kiziltepe T; Elford HL; Munshi NC; Anderson KC
Br J Haematol; 2006 Oct; 135(1):52-61. PubMed ID: 16925573
[TBL] [Abstract][Full Text] [Related]
18. Genotoxic properties of the newly synthesized antineoplastic agents amidox, didox and trimidox.
Miadoková E; Macáková K; Podstavková S; Vlcek D
Pharmazie; 1997 Jul; 52(7):540-4. PubMed ID: 9266591
[TBL] [Abstract][Full Text] [Related]
19. The effects of lithium in reversing hydroxyurea induced suppression of hematopoietic progenitor cells in vitro using retroviral infected long-term marrow cultures.
Oakley OR; Hughes NK; Phillips JD; Birch NJ; Gallicchio VS
Rom J Physiol; 1998; 35(1-2):67-78. PubMed ID: 11000867
[TBL] [Abstract][Full Text] [Related]
20. Inhibition of murine AIDS (MAIDS) development in C57BL/6J mice by tyrphostin AG-1387.
Sklan EH; Gazit A; Priel E
Virology; 2000 Dec; 278(1):95-102. PubMed ID: 11112485
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]