274 related articles for article (PubMed ID: 15132818)
1. Inactivation gating determines drug potency: a common mechanism for drug blockade of HERG channels.
Yang BF; Xu DH; Xu CQ; Li Z; Du ZM; Wang HZ; Dong DL
Acta Pharmacol Sin; 2004 May; 25(5):554-60. PubMed ID: 15132818
[TBL] [Abstract][Full Text] [Related]
2. Acidification alters antiarrhythmic drug blockade of the ether-a-go-go-related Gene (HERG) Channels.
Dong DL; Li Z; Wang HZ; Du ZM; Song WH; Yang BF
Basic Clin Pharmacol Toxicol; 2004 May; 94(5):209-12. PubMed ID: 15125690
[TBL] [Abstract][Full Text] [Related]
3. Molecular determinants of dofetilide block of HERG K+ channels.
Ficker E; Jarolimek W; Kiehn J; Baumann A; Brown AM
Circ Res; 1998 Feb; 82(3):386-95. PubMed ID: 9486667
[TBL] [Abstract][Full Text] [Related]
4. Inactivation gating determines nicotine blockade of human HERG channels.
Wang HZ; Shi H; Liao SJ; Wang Z
Am J Physiol; 1999 Sep; 277(3):H1081-8. PubMed ID: 10484431
[TBL] [Abstract][Full Text] [Related]
5. Dofetilide block involves interactions with open and inactivated states of HERG channels.
Weerapura M; Hébert TE; Nattel S
Pflugers Arch; 2002 Feb; 443(4):520-31. PubMed ID: 11907818
[TBL] [Abstract][Full Text] [Related]
6. Molecular determinants of inactivation and dofetilide block in ether a-go-go (EAG) channels and EAG-related K(+) channels.
Ficker E; Jarolimek W; Brown AM
Mol Pharmacol; 2001 Dec; 60(6):1343-8. PubMed ID: 11723241
[TBL] [Abstract][Full Text] [Related]
7. The influence of extracellular acidosis on the effect of IKr blockers.
Lin C; Ke X; Cvetanovic I; Ranade V; Somberg J
J Cardiovasc Pharmacol Ther; 2005 Mar; 10(1):67-76. PubMed ID: 15821840
[TBL] [Abstract][Full Text] [Related]
8. High-affinity blockade of human ether-a-go-go-related gene human cardiac potassium channels by the novel antiarrhythmic drug BRL-32872.
Thomas D; Wendt-Nordahl G; Röckl K; Ficker E; Brown AM; Kiehn J
J Pharmacol Exp Ther; 2001 May; 297(2):753-61. PubMed ID: 11303067
[TBL] [Abstract][Full Text] [Related]
9. Modulation of HERG potassium channels by extracellular magnesium and quinidine.
Po SS; Wang DW; Yang IC; Johnson JP; Nie L; Bennett PB
J Cardiovasc Pharmacol; 1999 Feb; 33(2):181-5. PubMed ID: 10028924
[TBL] [Abstract][Full Text] [Related]
10. Blockade of HERG channels by the class III antiarrhythmic azimilide: mode of action.
Busch AE; Eigenberger B; Jurkiewicz NK; Salata JJ; Pica A; Suessbrich H; Lang F
Br J Pharmacol; 1998 Jan; 123(1):23-30. PubMed ID: 9484850
[TBL] [Abstract][Full Text] [Related]
11. Pharmacological inhibition of the hERG potassium channel is modulated by extracellular but not intracellular acidosis.
DU CY; El Harchi A; Zhang YH; Orchard CH; Hancox JC
J Cardiovasc Electrophysiol; 2011 Oct; 22(10):1163-70. PubMed ID: 21489024
[TBL] [Abstract][Full Text] [Related]
12. Dissociation of E-4031 from the HERG channel caused by mutations of an amino acid results in greater block at high stimulation frequency.
Ishii K; Nagai M; Takahashi M; Endoh M
Cardiovasc Res; 2003 Mar; 57(3):651-9. PubMed ID: 12618227
[TBL] [Abstract][Full Text] [Related]
13. Mechanism of block and identification of the verapamil binding domain to HERG potassium channels.
Zhang S; Zhou Z; Gong Q; Makielski JC; January CT
Circ Res; 1999 May; 84(9):989-98. PubMed ID: 10325236
[TBL] [Abstract][Full Text] [Related]
14. Characterisation of recombinant HERG K+ channel blockade by the Class Ia antiarrhythmic drug procainamide.
Ridley JM; Milnes JT; Benest AV; Masters JD; Witchel HJ; Hancox JC
Biochem Biophys Res Commun; 2003 Jun; 306(2):388-93. PubMed ID: 12804575
[TBL] [Abstract][Full Text] [Related]
15. The effect of high extracellular potassium on IKr inhibition by anti-arrhythmic agents.
Lin C; Ke X; Cvetanovic I; Ranade V; Somberg J
Cardiology; 2007; 108(1):18-27. PubMed ID: 16960444
[TBL] [Abstract][Full Text] [Related]
16. Structural determinants of HERG channel block by clofilium and ibutilide.
Perry M; de Groot MJ; Helliwell R; Leishman D; Tristani-Firouzi M; Sanguinetti MC; Mitcheson J
Mol Pharmacol; 2004 Aug; 66(2):240-9. PubMed ID: 15266014
[TBL] [Abstract][Full Text] [Related]
17. Redox state dependency of HERGS631C channel pharmacology: relation to C-type inactivation.
Ulens C; Tytgat J
FEBS Lett; 2000 May; 474(1):111-5. PubMed ID: 10828461
[TBL] [Abstract][Full Text] [Related]
18. Altering extracellular potassium concentration does not modulate drug block of human ether-a-go-go-related gene (hERG) channels.
Limberis JT; Su Z; Cox BF; Gintant GA; Martin RL
Clin Exp Pharmacol Physiol; 2006 Nov; 33(11):1059-65. PubMed ID: 17042915
[TBL] [Abstract][Full Text] [Related]
19. Inactivation block of the HERG human cardiac K+ channels by RP58866.
Wang H; Shi H; Wang Z
Br J Pharmacol; 1999 Aug; 127(8):1899-907. PubMed ID: 10482922
[TBL] [Abstract][Full Text] [Related]
20. Protein kinase A-mediated phosphorylation of HERG potassium channels in a human cell line.
Wei Z; Thomas D; Karle CA; Kathöfer S; Schenkel J; Kreye VA; Ficker E; Wible BA; Kiehn J
Chin Med J (Engl); 2002 May; 115(5):668-76. PubMed ID: 12133532
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
