These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

124 related articles for article (PubMed ID: 15135057)

  • 1. Reconstitution and functional characterization of the unusual bi-subunit type I DNA topoisomerase from Leishmania donovani.
    Das BB; Sen N; Ganguly A; Majumder HK
    FEBS Lett; 2004 May; 565(1-3):81-8. PubMed ID: 15135057
    [TBL] [Abstract][Full Text] [Related]  

  • 2. An insight into the mechanism of inhibition of unusual bi-subunit topoisomerase I from Leishmania donovani by 3,3'-di-indolylmethane, a novel DNA topoisomerase I poison with a strong binding affinity to the enzyme.
    Roy A; Das BB; Ganguly A; Bose Dasgupta S; Khalkho NV; Pal C; Dey S; Giri VS; Jaisankar P; Dey S; Majumder HK
    Biochem J; 2008 Jan; 409(2):611-22. PubMed ID: 17922678
    [TBL] [Abstract][Full Text] [Related]  

  • 3. 'LeishMan' topoisomerase I: an ideal chimera for unraveling the role of the small subunit of unusual bi-subunit topoisomerase I from Leishmania donovani.
    Ganguly A; Das BB; Sen N; Roy A; Dasgupta SB; Majumder HK
    Nucleic Acids Res; 2006; 34(21):6286-97. PubMed ID: 17098934
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Structural insights on the small subunit of DNA topoisomerase I from the unicellular parasite Leishmania donovani.
    Díaz González R; Pérez Pertejo Y; Redondo CM; Pommier Y; Balaña-Fouce R; Reguera RM
    Biochimie; 2007 Dec; 89(12):1517-27. PubMed ID: 17900785
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The large subunit of Leishmania topoisomerase I functions as the 'molecular steer' in type IB topoisomerase.
    BoseDasgupta S; Ganguly A; Das BB; Roy A; Khalkho NV; Majumder HK
    Mol Microbiol; 2008 Jan; 67(1):31-46. PubMed ID: 18036140
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A type 1 DNA topoisomerase from the kinetoplast hemoflagellate Leishmania donovani.
    Chakraborty AK; Gupta A; Majumder HK
    Indian J Biochem Biophys; 1993 Oct; 30(5):257-63. PubMed ID: 8144168
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Differential induction of Leishmania donovani bi-subunit topoisomerase I-DNA cleavage complex by selected flavones and camptothecin: activity of flavones against camptothecin-resistant topoisomerase I.
    Das BB; Sen N; Roy A; Dasgupta SB; Ganguly A; Mohanta BC; Dinda B; Majumder HK
    Nucleic Acids Res; 2006; 34(4):1121-32. PubMed ID: 16488884
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Leishmania donovani bisubunit topoisomerase I gene fusion leads to an active enzyme with conserved type IB enzyme function.
    Das BB; Bose Dasgupta S; Ganguly A; Mazumder S; Roy A; Majumder HK
    FEBS J; 2007 Jan; 274(1):150-63. PubMed ID: 17222179
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The structure of the transition state of the heterodimeric topoisomerase I of Leishmania donovani as a vanadate complex with nicked DNA.
    Davies DR; Mushtaq A; Interthal H; Champoux JJ; Hol WG
    J Mol Biol; 2006 Apr; 357(4):1202-10. PubMed ID: 16487540
    [TBL] [Abstract][Full Text] [Related]  

  • 10. N-terminal region of the large subunit of Leishmania donovani bisubunit topoisomerase I is involved in DNA relaxation and interaction with the smaller subunit.
    Das BB; Sen N; Dasgupta SB; Ganguly A; Majumder HK
    J Biol Chem; 2005 Apr; 280(16):16335-44. PubMed ID: 15711017
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Human topoisomerase I forms double cleavage complexes on natural DNA.
    Søe K; Hartung S; Grosse F
    Biochem Biophys Res Commun; 2006 Oct; 349(1):178-85. PubMed ID: 16930551
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The lignan glycosides lyoniside and saracoside poison the unusual type IB topoisomerase of Leishmania donovani and kill the parasite both in vitro and in vivo.
    Saha S; Mukherjee T; Chowdhury S; Mishra A; Chowdhury SR; Jaisankar P; Mukhopadhyay S; Majumder HK
    Biochem Pharmacol; 2013 Dec; 86(12):1673-87. PubMed ID: 24134912
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Amino acids 39-456 of the large subunit and 210-262 of the small subunit constitute the minimal functionally interacting fragments of the unusual heterodimeric topoisomerase IB of Leishmania.
    Bosedasgupta S; Das BB; Sengupta S; Ganguly A; Roy A; Tripathi G; Majumder HK
    Biochem J; 2008 Jan; 409(2):481-9. PubMed ID: 17924857
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Reconstitution of human topoisomerase I by fragment complementation.
    Stewart L; Ireton GC; Champoux JJ
    J Mol Biol; 1997 Jun; 269(3):355-72. PubMed ID: 9199405
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Characterization of the ATPase activity of topoisomerase II from Leishmania donovani and identification of residues conferring resistance to etoposide.
    Sengupta T; Mukherjee M; Das A; Mandal C; Das R; Mukherjee T; Majumder HK
    Biochem J; 2005 Sep; 390(Pt 2):419-26. PubMed ID: 15901238
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Characterization of the DNA-binding domain and identification of the active site residue in the 'Gyr A' half of Leishmania donovani topoisomerase II.
    Sengupta T; Mukherjee M; Das R; Das A; Majumder HK
    Nucleic Acids Res; 2005; 33(8):2364-73. PubMed ID: 15860773
    [TBL] [Abstract][Full Text] [Related]  

  • 17. ATP independent type IB topoisomerase of Leishmania donovani is stimulated by ATP: an insight into the functional mechanism.
    Sengupta S; Ganguly A; Roy A; Bosedasgupta S; D'Annessa I; Desideri A; Majumder HK
    Nucleic Acids Res; 2011 Apr; 39(8):3295-309. PubMed ID: 21186185
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Synthesis, DNA binding, and Leishmania topoisomerase inhibition activities of a novel series of anthra[1,2-d]imidazole-6,11-dione derivatives.
    Chaudhuri P; Majumder HK; Bhattacharya S
    J Med Chem; 2007 May; 50(10):2536-40. PubMed ID: 17444624
    [TBL] [Abstract][Full Text] [Related]  

  • 19. A tyrosyl DNA phosphodiesterase 1 from kinetoplastid parasite Leishmania donovani (LdTdp1) capable of removing topo I-DNA covalent complexes.
    Banerjee B; Roy A; Sen N; Majumder HK
    Mol Microbiol; 2010 Oct; 78(1):119-37. PubMed ID: 20659295
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Mutational studies reveal lysine 352 on the large subunit is indispensable for catalytic activity of bi-subunit topoisomerase I from Leishmania donovani.
    Ganguly A; Sengupta S; Bosedasgupta S; Roy A; Majumder HK
    Mol Biochem Parasitol; 2009 May; 165(1):57-66. PubMed ID: 19393162
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.