251 related articles for article (PubMed ID: 15138591)
1. A G-quadruplex-interactive agent, telomestatin (SOT-095), induces telomere shortening with apoptosis and enhances chemosensitivity in acute myeloid leukemia.
Sumi M; Tauchi T; Sashida G; Nakajima A; Gotoh A; Shin-Ya K; Ohyashiki JH; Ohyashiki K
Int J Oncol; 2004 Jun; 24(6):1481-7. PubMed ID: 15138591
[TBL] [Abstract][Full Text] [Related]
2. Telomerase inhibition, telomere shortening, cell growth suppression and induction of apoptosis by telomestatin in childhood neuroblastoma cells.
Binz N; Shalaby T; Rivera P; Shin-ya K; Grotzer MA
Eur J Cancer; 2005 Dec; 41(18):2873-81. PubMed ID: 16253503
[TBL] [Abstract][Full Text] [Related]
3. Telomerase inhibition with a novel G-quadruplex-interactive agent, telomestatin: in vitro and in vivo studies in acute leukemia.
Tauchi T; Shin-ya K; Sashida G; Sumi M; Okabe S; Ohyashiki JH; Ohyashiki K
Oncogene; 2006 Sep; 25(42):5719-25. PubMed ID: 16652154
[TBL] [Abstract][Full Text] [Related]
4. Activity of a novel G-quadruplex-interactive telomerase inhibitor, telomestatin (SOT-095), against human leukemia cells: involvement of ATM-dependent DNA damage response pathways.
Tauchi T; Shin-Ya K; Sashida G; Sumi M; Nakajima A; Shimamoto T; Ohyashiki JH; Ohyashiki K
Oncogene; 2003 Aug; 22(34):5338-47. PubMed ID: 12917635
[TBL] [Abstract][Full Text] [Related]
5. The different biological effects of telomestatin and TMPyP4 can be attributed to their selectivity for interaction with intramolecular or intermolecular G-quadruplex structures.
Kim MY; Gleason-Guzman M; Izbicka E; Nishioka D; Hurley LH
Cancer Res; 2003 Jun; 63(12):3247-56. PubMed ID: 12810655
[TBL] [Abstract][Full Text] [Related]
6. [Telomerase inhibitor, telomestatin, a specific mechanism to interact with telomere structure].
Shin-ya K
Nihon Rinsho; 2004 Jul; 62(7):1277-82. PubMed ID: 15283144
[TBL] [Abstract][Full Text] [Related]
7. G-Quadruplex stabilization by telomestatin induces TRF2 protein dissociation from telomeres and anaphase bridge formation accompanied by loss of the 3' telomeric overhang in cancer cells.
Tahara H; Shin-Ya K; Seimiya H; Yamada H; Tsuruo T; Ide T
Oncogene; 2006 Mar; 25(13):1955-66. PubMed ID: 16302000
[TBL] [Abstract][Full Text] [Related]
8. The G-quadruplex ligand telomestatin inhibits POT1 binding to telomeric sequences in vitro and induces GFP-POT1 dissociation from telomeres in human cells.
Gomez D; O'Donohue MF; Wenner T; Douarre C; Macadré J; Koebel P; Giraud-Panis MJ; Kaplan H; Kolkes A; Shin-ya K; Riou JF
Cancer Res; 2006 Jul; 66(14):6908-12. PubMed ID: 16849533
[TBL] [Abstract][Full Text] [Related]
9. Telomerase inhibition enhances apoptosis in human acute leukemia cells: possibility of antitelomerase therapy.
Nakajima A; Tauchi T; Sashida G; Sumi M; Abe K; Yamamoto K; Ohyashiki JH; Ohyashiki K
Leukemia; 2003 Mar; 17(3):560-7. PubMed ID: 12646945
[TBL] [Abstract][Full Text] [Related]
10. Resistance to senescence induction and telomere shortening by a G-quadruplex ligand inhibitor of telomerase.
Gomez D; Aouali N; Renaud A; Douarre C; Shin-Ya K; Tazi J; Martinez S; Trentesaux C; Morjani H; Riou JF
Cancer Res; 2003 Oct; 63(19):6149-53. PubMed ID: 14559794
[TBL] [Abstract][Full Text] [Related]
11. Critically short telomeres in acute myeloid leukemia with loss or gain of parts of chromosomes.
Swiggers SJ; Kuijpers MA; de Cort MJ; Beverloo HB; Zijlmans JM
Genes Chromosomes Cancer; 2006 Mar; 45(3):247-56. PubMed ID: 16281260
[TBL] [Abstract][Full Text] [Related]
12. Human stem cell factor-antibody [anti-SCF] enhances chemotherapy cytotoxicity in human CD34+ resistant myeloid leukaemia cells.
Lu C; Hassan HT
Leuk Res; 2006 Mar; 30(3):296-302. PubMed ID: 16112192
[TBL] [Abstract][Full Text] [Related]
13. Affinity and selectivity of G4 ligands measured by FRET.
De Cian A; Guittat L; Shin-ya K; Riou JF; Mergny JL
Nucleic Acids Symp Ser (Oxf); 2005; (49):235-6. PubMed ID: 17150720
[TBL] [Abstract][Full Text] [Related]
14. Pharmacodynamics of the G-quadruplex-stabilizing telomerase inhibitor 3,11-difluoro-6,8,13-trimethyl-8H-quino[4,3,2-kl]acridinium methosulfate (RHPS4) in vitro: activity in human tumor cells correlates with telomere length and can be enhanced, or antagonized, with cytotoxic agents.
Cookson JC; Dai F; Smith V; Heald RA; Laughton CA; Stevens MF; Burger AM
Mol Pharmacol; 2005 Dec; 68(6):1551-8. PubMed ID: 16150933
[TBL] [Abstract][Full Text] [Related]
15. Apoptosis related to telomere instability and cell cycle alterations in human glioma cells treated by new highly selective G-quadruplex ligands.
Pennarun G; Granotier C; Gauthier LR; Gomez D; Hoffschir F; Mandine E; Riou JF; Mergny JL; Mailliet P; Boussin FD
Oncogene; 2005 Apr; 24(18):2917-28. PubMed ID: 15735722
[TBL] [Abstract][Full Text] [Related]
16. The telomerase inhibitor telomestatin induces telomere shortening and cell death in Arabidopsis.
Zhang L; Tamura K; Shin-ya K; Takahashi H
Biochim Biophys Acta; 2006 Jan; 1763(1):39-44. PubMed ID: 16473138
[TBL] [Abstract][Full Text] [Related]
17. Inhibition of human telomerase enhances the effect of chemotherapeutic agents in lung cancer cells.
Misawa M; Tauchi T; Sashida G; Nakajima A; Abe K; Ohyashiki JH; Ohyashiki K
Int J Oncol; 2002 Nov; 21(5):1087-92. PubMed ID: 12370759
[TBL] [Abstract][Full Text] [Related]
18. Energetics of the human Tel-22 quadruplex-telomestatin interaction: a molecular dynamics study.
Agrawal S; Ojha RP; Maiti S
J Phys Chem B; 2008 Jun; 112(22):6828-36. PubMed ID: 18461983
[TBL] [Abstract][Full Text] [Related]
19. Inhibition of telomerase limits the growth of human cancer cells.
Hahn WC; Stewart SA; Brooks MW; York SG; Eaton E; Kurachi A; Beijersbergen RL; Knoll JH; Meyerson M; Weinberg RA
Nat Med; 1999 Oct; 5(10):1164-70. PubMed ID: 10502820
[TBL] [Abstract][Full Text] [Related]
20. Telomerase antagonists GRN163 and GRN163L inhibit tumor growth and increase chemosensitivity of human hepatoma.
Djojosubroto MW; Chin AC; Go N; Schaetzlein S; Manns MP; Gryaznov S; Harley CB; Rudolph KL
Hepatology; 2005 Nov; 42(5):1127-36. PubMed ID: 16114043
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
