214 related articles for article (PubMed ID: 15144219)
1. Metabolism is required for the expression of ecstasy-induced cardiotoxicity in vitro.
Carvalho M; Remião F; Milhazes N; Borges F; Fernandes E; Monteiro Mdo C; Gonçalves MJ; Seabra V; Amado F; Carvalho F; Bastos ML
Chem Res Toxicol; 2004 May; 17(5):623-32. PubMed ID: 15144219
[TBL] [Abstract][Full Text] [Related]
2. The toxicity of N-methyl-alpha-methyldopamine to freshly isolated rat hepatocytes is prevented by ascorbic acid and N-acetylcysteine.
Carvalho M; Remião F; Milhazes N; Borges F; Fernandes E; Carvalho F; Bastos ML
Toxicology; 2004 Aug; 200(2-3):193-203. PubMed ID: 15212815
[TBL] [Abstract][Full Text] [Related]
3. Hepatotoxicity of 3,4-methylenedioxyamphetamine and alpha-methyldopamine in isolated rat hepatocytes: formation of glutathione conjugates.
Carvalho M; Milhazes N; Remião F; Borges F; Fernandes E; Amado F; Monks TJ; Carvalho F; Bastos ML
Arch Toxicol; 2004 Jan; 78(1):16-24. PubMed ID: 14586543
[TBL] [Abstract][Full Text] [Related]
4. Neurotoxicity mechanisms of thioether ecstasy metabolites.
Capela JP; Macedo C; Branco PS; Ferreira LM; Lobo AM; Fernandes E; Remião F; Bastos ML; Dirnagl U; Meisel A; Carvalho F
Neuroscience; 2007 Jun; 146(4):1743-57. PubMed ID: 17467183
[TBL] [Abstract][Full Text] [Related]
5. Role of metabolites in MDMA (ecstasy)-induced nephrotoxicity: an in vitro study using rat and human renal proximal tubular cells.
Carvalho M; Hawksworth G; Milhazes N; Borges F; Monks TJ; Fernandes E; Carvalho F; Bastos ML
Arch Toxicol; 2002 Oct; 76(10):581-8. PubMed ID: 12373454
[TBL] [Abstract][Full Text] [Related]
6. Neurotoxicity of Ecstasy metabolites in rat cortical neurons, and influence of hyperthermia.
Capela JP; Meisel A; Abreu AR; Branco PS; Ferreira LM; Lobo AM; Remião F; Bastos ML; Carvalho F
J Pharmacol Exp Ther; 2006 Jan; 316(1):53-61. PubMed ID: 16183702
[TBL] [Abstract][Full Text] [Related]
7. "Ecstasy"-induced toxicity in SH-SY5Y differentiated cells: role of hyperthermia and metabolites.
Barbosa DJ; Capela JP; Silva R; Ferreira LM; Branco PS; Fernandes E; Bastos ML; Carvalho F
Arch Toxicol; 2014 Feb; 88(2):515-31. PubMed ID: 24177245
[TBL] [Abstract][Full Text] [Related]
8. Effects of intracerebroventricular administration of 5-(glutathion-S-yl)-alpha-methyldopamine on brain dopamine, serotonin, and norepinephrine concentrations in male Sprague-Dawley rats.
Miller RT; Lau SS; Monks TJ
Chem Res Toxicol; 1996 Mar; 9(2):457-65. PubMed ID: 8839050
[TBL] [Abstract][Full Text] [Related]
9. Thioether metabolites of 3,4-methylenedioxyamphetamine and 3,4-methylenedioxymethamphetamine inhibit human serotonin transporter (hSERT) function and simultaneously stimulate dopamine uptake into hSERT-expressing SK-N-MC cells.
Jones DC; Lau SS; Monks TJ
J Pharmacol Exp Ther; 2004 Oct; 311(1):298-306. PubMed ID: 15169827
[TBL] [Abstract][Full Text] [Related]
10. Glutathione and N-acetylcysteine conjugates of alpha-methyldopamine produce serotonergic neurotoxicity: possible role in methylenedioxyamphetamine-mediated neurotoxicity.
Bai F; Lau SS; Monks TJ
Chem Res Toxicol; 1999 Dec; 12(12):1150-7. PubMed ID: 10604863
[TBL] [Abstract][Full Text] [Related]
11. Induction of glutathione synthesis and conjugation by 3,4-methylenedioxymethamphetamine (MDMA) and 3,4-dihydroxymethamphetamine (HHMA) in human and rat liver cells, including the protective role of some antioxidants.
Antolino-Lobo I; Meulenbelt J; Molendijk J; Nijmeijer SM; Scherpenisse P; van den Berg M; van Duursen MB
Toxicology; 2011 Nov; 289(2-3):175-84. PubMed ID: 21871945
[TBL] [Abstract][Full Text] [Related]
12. Neurotoxicity of "ecstasy" and its metabolites in human dopaminergic differentiated SH-SY5Y cells.
Ferreira PS; Nogueira TB; Costa VM; Branco PS; Ferreira LM; Fernandes E; Bastos ML; Meisel A; Carvalho F; Capela JP
Toxicol Lett; 2013 Feb; 216(2-3):159-70. PubMed ID: 23194825
[TBL] [Abstract][Full Text] [Related]
13. Mixtures of 3,4-methylenedioxymethamphetamine (ecstasy) and its major human metabolites act additively to induce significant toxicity to liver cells when combined at low, non-cytotoxic concentrations.
da Silva DD; Silva E; Carvalho F; Carmo H
J Appl Toxicol; 2014 Jun; 34(6):618-27. PubMed ID: 23670916
[TBL] [Abstract][Full Text] [Related]
14. Synthesis, in vitro formation, and behavioural effects of glutathione regioisomers of alpha-methyldopamine with relevance to MDA and MDMA (ecstasy).
Easton N; Fry J; O'Shea E; Watkins A; Kingston S; Marsden CA
Brain Res; 2003 Oct; 987(2):144-54. PubMed ID: 14499958
[TBL] [Abstract][Full Text] [Related]
15. Pro-oxidant effects of Ecstasy and its metabolites in mouse brain synaptosomes.
Barbosa DJ; Capela JP; Oliveira JM; Silva R; Ferreira LM; Siopa F; Branco PS; Fernandes E; Duarte JA; de Lourdes Bastos M; Carvalho F
Br J Pharmacol; 2012 Feb; 165(4b):1017-33. PubMed ID: 21506960
[TBL] [Abstract][Full Text] [Related]
16. Serotonergic neurotoxic metabolites of ecstasy identified in rat brain.
Jones DC; Duvauchelle C; Ikegami A; Olsen CM; Lau SS; de la Torre R; Monks TJ
J Pharmacol Exp Ther; 2005 Apr; 313(1):422-31. PubMed ID: 15634943
[TBL] [Abstract][Full Text] [Related]
17. 2,5-Bis-(glutathion-S-yl)-alpha-methyldopamine, a putative metabolite of (+/-)-3,4-methylenedioxyamphetamine, decreases brain serotonin concentrations.
Miller RT; Lau SS; Monks TJ
Eur J Pharmacol; 1997 Apr; 323(2-3):173-80. PubMed ID: 9128836
[TBL] [Abstract][Full Text] [Related]
18. Synthesis and cytotoxic profile of 3,4-methylenedioxymethamphetamine ("ecstasy") and its metabolites on undifferentiated PC12 cells: A putative structure-toxicity relationship.
Milhazes N; Cunha-Oliveira T; Martins P; Garrido J; Oliveira C; Rego AC; Borges F
Chem Res Toxicol; 2006 Oct; 19(10):1294-304. PubMed ID: 17040098
[TBL] [Abstract][Full Text] [Related]
19. The role of metabolism in 3,4-(+)-methylenedioxyamphetamine and 3,4-(+)-methylenedioxymethamphetamine (ecstasy) toxicity.
Monks TJ; Jones DC; Bai F; Lau SS
Ther Drug Monit; 2004 Apr; 26(2):132-6. PubMed ID: 15228153
[TBL] [Abstract][Full Text] [Related]
20. Accumulation of neurotoxic thioether metabolites of 3,4-(+/-)-methylenedioxymethamphetamine in rat brain.
Erives GV; Lau SS; Monks TJ
J Pharmacol Exp Ther; 2008 Jan; 324(1):284-91. PubMed ID: 17906065
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
