969 related articles for article (PubMed ID: 15150094)
1. Different effects of point mutations within the B-Raf glycine-rich loop in colorectal tumors on mitogen-activated protein/extracellular signal-regulated kinase kinase/extracellular signal-regulated kinase and nuclear factor kappaB pathway and cellular transformation.
Ikenoue T; Hikiba Y; Kanai F; Aragaki J; Tanaka Y; Imamura J; Imamura T; Ohta M; Ijichi H; Tateishi K; Kawakami T; Matsumura M; Kawabe T; Omata M
Cancer Res; 2004 May; 64(10):3428-35. PubMed ID: 15150094
[TBL] [Abstract][Full Text] [Related]
2. Functional analysis of mutations within the kinase activation segment of B-Raf in human colorectal tumors.
Ikenoue T; Hikiba Y; Kanai F; Tanaka Y; Imamura J; Imamura T; Ohta M; Ijichi H; Tateishi K; Kawakami T; Aragaki J; Matsumura M; Kawabe T; Omata M
Cancer Res; 2003 Dec; 63(23):8132-7. PubMed ID: 14678966
[TBL] [Abstract][Full Text] [Related]
3. Radicicol suppresses transformation and restores tropomyosin-2 expression in both ras- and MEK-transformed cells without inhibiting the Raf/MEK/ERK signaling cascade.
Kim PN; Jonasch E; Mosterman BC; Mier JW; Janssen RA
Cell Growth Differ; 2001 Nov; 12(11):543-50. PubMed ID: 11714635
[TBL] [Abstract][Full Text] [Related]
4. Induction of beta3-integrin gene expression by sustained activation of the Ras-regulated Raf-MEK-extracellular signal-regulated kinase signaling pathway.
Woods D; Cherwinski H; Venetsanakos E; Bhat A; Gysin S; Humbert M; Bray PF; Saylor VL; McMahon M
Mol Cell Biol; 2001 May; 21(9):3192-205. PubMed ID: 11287623
[TBL] [Abstract][Full Text] [Related]
5. Two transforming C-RAF germ-line mutations identified in patients with therapy-related acute myeloid leukemia.
Zebisch A; Staber PB; Delavar A; Bodner C; Hiden K; Fischereder K; Janakiraman M; Linkesch W; Auner HW; Emberger W; Windpassinger C; Schimek MG; Hoefler G; Troppmair J; Sill H
Cancer Res; 2006 Apr; 66(7):3401-8. PubMed ID: 16585161
[TBL] [Abstract][Full Text] [Related]
6. A Raf-1 mutant that dissociates MEK/extracellular signal-regulated kinase activation from malignant transformation and differentiation but not proliferation.
Dhillon AS; Meikle S; Peyssonnaux C; Grindlay J; Kaiser C; Steen H; Shaw PE; Mischak H; Eychène A; Kolch W
Mol Cell Biol; 2003 Mar; 23(6):1983-93. PubMed ID: 12612072
[TBL] [Abstract][Full Text] [Related]
7. Curcumin-induced antiproliferative and proapoptotic effects in melanoma cells are associated with suppression of IkappaB kinase and nuclear factor kappaB activity and are independent of the B-Raf/mitogen-activated/extracellular signal-regulated protein kinase pathway and the Akt pathway.
Siwak DR; Shishodia S; Aggarwal BB; Kurzrock R
Cancer; 2005 Aug; 104(4):879-90. PubMed ID: 16007726
[TBL] [Abstract][Full Text] [Related]
8. Rit, a non-lipid-modified Ras-related protein, transforms NIH3T3 cells without activating the ERK, JNK, p38 MAPK or PI3K/Akt pathways.
Rusyn EV; Reynolds ER; Shao H; Grana TM; Chan TO; Andres DA; Cox AD
Oncogene; 2000 Sep; 19(41):4685-94. PubMed ID: 11032018
[TBL] [Abstract][Full Text] [Related]
9. Mechanism of activation of the RAF-ERK signaling pathway by oncogenic mutations of B-RAF.
Wan PT; Garnett MJ; Roe SM; Lee S; Niculescu-Duvaz D; Good VM; Jones CM; Marshall CJ; Springer CJ; Barford D; Marais R;
Cell; 2004 Mar; 116(6):855-67. PubMed ID: 15035987
[TBL] [Abstract][Full Text] [Related]
10. Functional consequences of mutations in a putative Akt phosphorylation motif of B-raf in human cancers.
Ikenoue T; Kanai F; Hikiba Y; Tanaka Y; Imamura J; Ohta M; Jazag A; Guleng B; Asaoka Y; Tateishi K; Kawakami T; Matsumura M; Kawabe T; Omata M
Mol Carcinog; 2005 May; 43(1):59-63. PubMed ID: 15791648
[TBL] [Abstract][Full Text] [Related]
11. Mutations in conserved regions 1, 2, and 3 of Raf-1 that activate transforming activity.
Chan EY; Stang SL; Bottorff DA; Stone JC
Mol Carcinog; 2002 Apr; 33(4):189-97. PubMed ID: 11933072
[TBL] [Abstract][Full Text] [Related]
12. Mutation of B-Raf in human choroidal melanoma cells mediates cell proliferation and transformation through the MEK/ERK pathway.
Calipel A; Lefevre G; Pouponnot C; Mouriaux F; Eychène A; Mascarelli F
J Biol Chem; 2003 Oct; 278(43):42409-18. PubMed ID: 12917419
[TBL] [Abstract][Full Text] [Related]
13. Mutations of the BRAF gene in human cancer.
Davies H; Bignell GR; Cox C; Stephens P; Edkins S; Clegg S; Teague J; Woffendin H; Garnett MJ; Bottomley W; Davis N; Dicks E; Ewing R; Floyd Y; Gray K; Hall S; Hawes R; Hughes J; Kosmidou V; Menzies A; Mould C; Parker A; Stevens C; Watt S; Hooper S; Wilson R; Jayatilake H; Gusterson BA; Cooper C; Shipley J; Hargrave D; Pritchard-Jones K; Maitland N; Chenevix-Trench G; Riggins GJ; Bigner DD; Palmieri G; Cossu A; Flanagan A; Nicholson A; Ho JW; Leung SY; Yuen ST; Weber BL; Seigler HF; Darrow TL; Paterson H; Marais R; Marshall CJ; Wooster R; Stratton MR; Futreal PA
Nature; 2002 Jun; 417(6892):949-54. PubMed ID: 12068308
[TBL] [Abstract][Full Text] [Related]
14. Similarity of the phenotypic patterns associated with BRAF and KRAS mutations in colorectal neoplasia.
Yuen ST; Davies H; Chan TL; Ho JW; Bignell GR; Cox C; Stephens P; Edkins S; Tsui WW; Chan AS; Futreal PA; Stratton MR; Wooster R; Leung SY
Cancer Res; 2002 Nov; 62(22):6451-5. PubMed ID: 12438234
[TBL] [Abstract][Full Text] [Related]
15. K-ras codon 12 mutation induces higher level of resistance to apoptosis and predisposition to anchorage-independent growth than codon 13 mutation or proto-oncogene overexpression.
Guerrero S; Casanova I; Farré L; Mazo A; Capellà G; Mangues R
Cancer Res; 2000 Dec; 60(23):6750-6. PubMed ID: 11118062
[TBL] [Abstract][Full Text] [Related]
16. Ras mediates radioresistance through both phosphatidylinositol 3-kinase-dependent and Raf-dependent but mitogen-activated protein kinase/extracellular signal-regulated kinase kinase-independent signaling pathways.
Grana TM; Rusyn EV; Zhou H; Sartor CI; Cox AD
Cancer Res; 2002 Jul; 62(14):4142-50. PubMed ID: 12124353
[TBL] [Abstract][Full Text] [Related]
17. Inhibition of the Raf/MEK/ERK pathway up-regulates expression of the coxsackievirus and adenovirus receptor in cancer cells.
Anders M; Christian C; McMahon M; McCormick F; Korn WM
Cancer Res; 2003 May; 63(9):2088-95. PubMed ID: 12727824
[TBL] [Abstract][Full Text] [Related]
18. Lysyl oxidase inhibits ras-mediated transformation by preventing activation of NF-kappa B.
Jeay S; Pianetti S; Kagan HM; Sonenshein GE
Mol Cell Biol; 2003 Apr; 23(7):2251-63. PubMed ID: 12640111
[TBL] [Abstract][Full Text] [Related]
19. Differential contribution of the ERK and JNK mitogen-activated protein kinase cascades to Ras transformation of HT1080 fibrosarcoma and DLD-1 colon carcinoma cells.
Plattner R; Gupta S; Khosravi-Far R; Sato KY; Perucho M; Der CJ; Stanbridge EJ
Oncogene; 1999 Mar; 18(10):1807-17. PubMed ID: 10086335
[TBL] [Abstract][Full Text] [Related]
20. Nuclear factor-kappaB is constitutively active in C-cell carcinoma and required for RET-induced transformation.
Ludwig L; Kessler H; Wagner M; Hoang-Vu C; Dralle H; Adler G; Böhm BO; Schmid RM
Cancer Res; 2001 Jun; 61(11):4526-35. PubMed ID: 11389085
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]