174 related articles for article (PubMed ID: 15161934)
1. IC101 induces apoptosis by Akt dephosphorylation via an inhibition of heat shock protein 90-ATP binding activity accompanied by preventing the interaction with Akt in L1210 cells.
Fujiwara H; Yamakuni T; Ueno M; Ishizuka M; Shinkawa T; Isobe T; Ohizumi Y
J Pharmacol Exp Ther; 2004 Sep; 310(3):1288-95. PubMed ID: 15161934
[TBL] [Abstract][Full Text] [Related]
2. Phosphatidylinositol 3-kinase (PI-3K)/Akt but not PI-3K/p70 S6 kinase signaling mediates IGF-1-promoted lens epithelial cell survival.
Chandrasekher G; Sailaja D
Invest Ophthalmol Vis Sci; 2004 Oct; 45(10):3577-88. PubMed ID: 15452065
[TBL] [Abstract][Full Text] [Related]
3. Inhibition of heat shock protein 90 function by 17-allylamino-17-demethoxy-geldanamycin in Hodgkin's lymphoma cells down-regulates Akt kinase, dephosphorylates extracellular signal-regulated kinase, and induces cell cycle arrest and cell death.
Georgakis GV; Li Y; Rassidakis GZ; Martinez-Valdez H; Medeiros LJ; Younes A
Clin Cancer Res; 2006 Jan; 12(2):584-90. PubMed ID: 16428504
[TBL] [Abstract][Full Text] [Related]
4. Modulation of Akt kinase activity by binding to Hsp90.
Sato S; Fujita N; Tsuruo T
Proc Natl Acad Sci U S A; 2000 Sep; 97(20):10832-7. PubMed ID: 10995457
[TBL] [Abstract][Full Text] [Related]
5. Sensitization of mesothelioma cells to tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis by heat stress via the inhibition of the 3-phosphoinositide-dependent kinase 1/Akt pathway.
Pespeni MH; Hodnett M; Abayasiriwardana KS; Roux J; Howard M; Broaddus VC; Pittet JF
Cancer Res; 2007 Mar; 67(6):2865-71. PubMed ID: 17363610
[TBL] [Abstract][Full Text] [Related]
6. Stimulated HSP90 binding to eNOS and activation of the PI3-Akt pathway contribute to globular adiponectin-induced NO production: vasorelaxation in response to globular adiponectin.
Xi W; Satoh H; Kase H; Suzuki K; Hattori Y
Biochem Biophys Res Commun; 2005 Jun; 332(1):200-5. PubMed ID: 15896318
[TBL] [Abstract][Full Text] [Related]
7. IL-7 inhibits dexamethasone-induced apoptosis via Akt/PKB in mature, peripheral T cells.
Sade H; Sarin A
Eur J Immunol; 2003 Apr; 33(4):913-9. PubMed ID: 12672057
[TBL] [Abstract][Full Text] [Related]
8. Down-regulation of Mcl-1 by inhibition of the PI3-K/Akt pathway is required for cell shrinkage-dependent cell death.
Araki T; Hayashi M; Watanabe N; Kanuka H; Yoshino J; Miura M; Saruta T
Biochem Biophys Res Commun; 2002 Feb; 290(4):1275-81. PubMed ID: 11812001
[TBL] [Abstract][Full Text] [Related]
9. Anti-apoptotic effect of heat shock protein 90 on hypoxia-mediated cardiomyocyte damage is mediated via the phosphatidylinositol 3-kinase/AKT pathway.
Wang W; Peng Y; Wang Y; Zhao X; Yuan Z
Clin Exp Pharmacol Physiol; 2009 Sep; 36(9):899-903. PubMed ID: 19298537
[TBL] [Abstract][Full Text] [Related]
10. Simvastatin induces proliferation inhibition and apoptosis in C6 glioma cells via c-jun N-terminal kinase.
Koyuturk M; Ersoz M; Altiok N
Neurosci Lett; 2004 Nov; 370(2-3):212-7. PubMed ID: 15488325
[TBL] [Abstract][Full Text] [Related]
11. SHP-1 sensitizes MCF-7 cells to trichostatin A-induced apoptosis by modulating PI3K-dependent events.
Xu Y; Mousseau DD; Banville D; Zhao X; Shen SH
Cell Death Differ; 2003 Oct; 10(10):1213-4. PubMed ID: 14502244
[No Abstract] [Full Text] [Related]
12. Hsp90 functions to balance the phosphorylation state of Akt during C2C12 myoblast differentiation.
Yun BG; Matts RL
Cell Signal; 2005 Dec; 17(12):1477-85. PubMed ID: 15935620
[TBL] [Abstract][Full Text] [Related]
13. Suppression of apoptosis by UVB irradiation: survival signaling via PI3-kinase/Akt pathway.
Ibuki Y; Goto R
Biochem Biophys Res Commun; 2000 Dec; 279(3):872-8. PubMed ID: 11162442
[TBL] [Abstract][Full Text] [Related]
14. The integrity of cholesterol-enriched microdomains is essential for the constitutive high activity of protein kinase B in tumour cells.
Elhyany S; Assa-Kunik E; Tsory S; Muller T; Fedida S; Segal S; Fishman D
Biochem Soc Trans; 2004 Nov; 32(Pt 5):837-9. PubMed ID: 15494028
[TBL] [Abstract][Full Text] [Related]
15. Inhibition of cell death by a novel 16.2 kD heat shock protein predominantly via Hsp90 mediated lipid rafts stabilization and Akt activation pathway.
Bellyei S; Szigeti A; Boronkai A; Pozsgai E; Gomori E; Melegh B; Janaky T; Bognar Z; Hocsak E; Sumegi B; Gallyas F
Apoptosis; 2007 Jan; 12(1):97-112. PubMed ID: 17136496
[TBL] [Abstract][Full Text] [Related]
16. The heat-shock protein 90 inhibitor, geldanamycin, induces apoptotic cell death in Epstein-Barr virus-positive NK/T-cell lymphoma by Akt down-regulation.
Jeon YK; Park CH; Kim KY; Li YC; Kim J; Kim YA; Paik JH; Park BK; Kim CW; Kim YN
J Pathol; 2007 Oct; 213(2):170-9. PubMed ID: 17768706
[TBL] [Abstract][Full Text] [Related]
17. Mahanine inhibits growth and induces apoptosis in prostate cancer cells through the deactivation of Akt and activation of caspases.
Sinha S; Pal BC; Jagadeesh S; Banerjee PP; Bandyopadhaya A; Bhattacharya S
Prostate; 2006 Sep; 66(12):1257-65. PubMed ID: 16683271
[TBL] [Abstract][Full Text] [Related]
18. Differential effects of Hsp90 inhibition on protein kinases regulating signal transduction pathways required for myoblast differentiation.
Yun BG; Matts RL
Exp Cell Res; 2005 Jul; 307(1):212-23. PubMed ID: 15922741
[TBL] [Abstract][Full Text] [Related]
19. A novel, small molecule inhibitor of Hsc70/Hsp70 potentiates Hsp90 inhibitor induced apoptosis in HCT116 colon carcinoma cells.
Massey AJ; Williamson DS; Browne H; Murray JB; Dokurno P; Shaw T; Macias AT; Daniels Z; Geoffroy S; Dopson M; Lavan P; Matassova N; Francis GL; Graham CJ; Parsons R; Wang Y; Padfield A; Comer M; Drysdale MJ; Wood M
Cancer Chemother Pharmacol; 2010 Aug; 66(3):535-45. PubMed ID: 20012863
[TBL] [Abstract][Full Text] [Related]
20. Inhibition of signal transduction by the Hsp90 inhibitor 17-allylamino-17-demethoxygeldanamycin results in cytostasis and apoptosis.
Hostein I; Robertson D; DiStefano F; Workman P; Clarke PA
Cancer Res; 2001 May; 61(10):4003-9. PubMed ID: 11358818
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]