585 related articles for article (PubMed ID: 15165029)
1. Functional characterization of sphingosine 1-phosphate receptor agonist in human endothelial cells.
Butler J; Lana D; Round O; LaMontagne K
Prostaglandins Other Lipid Mediat; 2004 Jan; 73(1-2):29-45. PubMed ID: 15165029
[TBL] [Abstract][Full Text] [Related]
2. Phosphorylation and action of the immunomodulator FTY720 inhibits vascular endothelial cell growth factor-induced vascular permeability.
Sanchez T; Estrada-Hernandez T; Paik JH; Wu MT; Venkataraman K; Brinkmann V; Claffey K; Hla T
J Biol Chem; 2003 Nov; 278(47):47281-90. PubMed ID: 12954648
[TBL] [Abstract][Full Text] [Related]
3. Molecular targets of FTY720 (fingolimod).
Pitman MR; Woodcock JM; Lopez AF; Pitson SM
Curr Mol Med; 2012 Dec; 12(10):1207-19. PubMed ID: 22834825
[TBL] [Abstract][Full Text] [Related]
4. Effects of phosphorylation of immunomodulatory agent FTY720 (fingolimod) on antiproliferative activity against breast and colon cancer cells.
Nagaoka Y; Otsuki K; Fujita T; Uesato S
Biol Pharm Bull; 2008 Jun; 31(6):1177-81. PubMed ID: 18520051
[TBL] [Abstract][Full Text] [Related]
5. Endothelial barrier protection by FTY720 under hyperglycemic condition: involvement of focal adhesion kinase, small GTPases, and adherens junction proteins.
Sarai K; Shikata K; Shikata Y; Omori K; Watanabe N; Sasaki M; Nishishita S; Wada J; Goda N; Kataoka N; Makino H
Am J Physiol Cell Physiol; 2009 Oct; 297(4):C945-54. PubMed ID: 19657053
[TBL] [Abstract][Full Text] [Related]
6. Targeting sphingosine-1-phosphate in hematologic malignancies.
Stevenson CE; Takabe K; Nagahashi M; Milstien S; Spiegel S
Anticancer Agents Med Chem; 2011 Nov; 11(9):794-8. PubMed ID: 21707492
[TBL] [Abstract][Full Text] [Related]
7. Sphingosine signalling regulates decidual NK cell angiogenic phenotype and trophoblast migration.
Zhang J; Dunk CE; Lye SJ
Hum Reprod; 2013 Nov; 28(11):3026-37. PubMed ID: 24001716
[TBL] [Abstract][Full Text] [Related]
8. Mapping pathways downstream of sphingosine 1-phosphate subtype 1 by differential chemical perturbation and proteomics.
Gonzalez-Cabrera PJ; Hla T; Rosen H
J Biol Chem; 2007 Mar; 282(10):7254-64. PubMed ID: 17218309
[TBL] [Abstract][Full Text] [Related]
9. Production and release of sphingosine 1-phosphate and the phosphorylated form of the immunomodulator FTY720.
Kihara A; Igarashi Y
Biochim Biophys Acta; 2008 Sep; 1781(9):496-502. PubMed ID: 18555808
[TBL] [Abstract][Full Text] [Related]
10. FTY720: sphingosine 1-phosphate receptor-1 in the control of lymphocyte egress and endothelial barrier function.
Brinkmann V; Cyster JG; Hla T
Am J Transplant; 2004 Jul; 4(7):1019-25. PubMed ID: 15196057
[TBL] [Abstract][Full Text] [Related]
11. FTY720 inhibits S1P-mediated endothelial healing: relationship to S1P1-receptor surface expression.
Krump-Konvalinkova V; Chwalla I; Siess W
Biochem Biophys Res Commun; 2008 Jun; 370(4):603-8. PubMed ID: 18402775
[TBL] [Abstract][Full Text] [Related]
12. The immunomodulator FTY720 and its phosphorylated derivative activate the Smad signalling cascade and upregulate connective tissue growth factor and collagen type IV expression in renal mesangial cells.
Xin C; Ren S; Eberhardt W; Pfeilschifter J; Huwiler A
Br J Pharmacol; 2006 Jan; 147(2):164-74. PubMed ID: 16299553
[TBL] [Abstract][Full Text] [Related]
13. FTY720 inhibits ceramide synthases and up-regulates dihydrosphingosine 1-phosphate formation in human lung endothelial cells.
Berdyshev EV; Gorshkova I; Skobeleva A; Bittman R; Lu X; Dudek SM; Mirzapoiazova T; Garcia JG; Natarajan V
J Biol Chem; 2009 Feb; 284(9):5467-77. PubMed ID: 19119142
[TBL] [Abstract][Full Text] [Related]
14. Sphingosine-1-phosphate, FTY720, and sphingosine-1-phosphate receptors in the pathobiology of acute lung injury.
Natarajan V; Dudek SM; Jacobson JR; Moreno-Vinasco L; Huang LS; Abassi T; Mathew B; Zhao Y; Wang L; Bittman R; Weichselbaum R; Berdyshev E; Garcia JG
Am J Respir Cell Mol Biol; 2013 Jul; 49(1):6-17. PubMed ID: 23449739
[TBL] [Abstract][Full Text] [Related]
15. Antagonism of sphingosine-1-phosphate receptors by FTY720 inhibits angiogenesis and tumor vascularization.
LaMontagne K; Littlewood-Evans A; Schnell C; O'Reilly T; Wyder L; Sanchez T; Probst B; Butler J; Wood A; Liau G; Billy E; Theuer A; Hla T; Wood J
Cancer Res; 2006 Jan; 66(1):221-31. PubMed ID: 16397235
[TBL] [Abstract][Full Text] [Related]
16. Synthesis of 4(5)-phenylimidazole-based analogues of sphingosine-1-phosphate and FTY720: discovery of potent S1P1 receptor agonists.
Clemens JJ; Davis MD; Lynch KR; Macdonald TL
Bioorg Med Chem Lett; 2005 Aug; 15(15):3568-72. PubMed ID: 15982878
[TBL] [Abstract][Full Text] [Related]
17. Immunosuppressive and anti-angiogenic sphingosine 1-phosphate receptor-1 agonists induce ubiquitinylation and proteasomal degradation of the receptor.
Oo ML; Thangada S; Wu MT; Liu CH; Macdonald TL; Lynch KR; Lin CY; Hla T
J Biol Chem; 2007 Mar; 282(12):9082-9. PubMed ID: 17237497
[TBL] [Abstract][Full Text] [Related]
18. Cis-4-methylsphingosine is a sphingosine-1-phosphate receptor modulator.
Ter Braak M; Claas RF; Hegen B; Labocha S; Ferreirós N; Pfeilschifter J; Huwiler A; van Echten-Deckert G; Meyer Zu Heringdorf D
Biochem Pharmacol; 2011 Mar; 81(5):617-25. PubMed ID: 21163254
[TBL] [Abstract][Full Text] [Related]
19. Individual variation of human S1P₁ coding sequence leads to heterogeneity in receptor function and drug interactions.
Obinata H; Gutkind S; Stitham J; Okuno T; Yokomizo T; Hwa J; Hla T
J Lipid Res; 2014 Dec; 55(12):2665-75. PubMed ID: 25293589
[TBL] [Abstract][Full Text] [Related]
20. Essential requirement for sphingosine kinase 2 in a sphingolipid apoptosis pathway activated by FTY720 analogues.
Don AS; Martinez-Lamenca C; Webb WR; Proia RL; Roberts E; Rosen H
J Biol Chem; 2007 May; 282(21):15833-42. PubMed ID: 17400555
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
