334 related articles for article (PubMed ID: 15165132)
21. Coumarin-derived discodermolide analogues possessing equivalent antiproliferative activity to the natural product--a further simplification of the lactone region.
Shaw SJ; Menzella HG; Myles DC; Xian M; Smith AB
Org Biomol Chem; 2007 Sep; 5(17):2753-5. PubMed ID: 17700839
[TBL] [Abstract][Full Text] [Related]
22. Conception, synthesis, and biological evaluation of original discodermolide analogues.
de Lemos E; Agouridas E; Sorin G; Guerreiro A; Commerçon A; Pancrazi A; Betzer JF; Lannou MI; Ardisson J
Chemistry; 2011 Aug; 17(36):10123-34. PubMed ID: 21793059
[TBL] [Abstract][Full Text] [Related]
23. Total synthesis and biological evaluation of a series of macrocyclic hybrids and analogues of the antimitotic natural products dictyostatin, discodermolide, and taxol.
Paterson I; Naylor GJ; Gardner NM; Guzmán E; Wright AE
Chem Asian J; 2011 Feb; 6(2):459-73. PubMed ID: 21254424
[TBL] [Abstract][Full Text] [Related]
24. Toward a commercial synthesis of (+)-discodermolide.
Mickel SJ
Curr Opin Drug Discov Devel; 2004 Nov; 7(6):869-81. PubMed ID: 15595446
[TBL] [Abstract][Full Text] [Related]
25. The structure activity relationship of discodermolide analogues.
Shaw SJ
Mini Rev Med Chem; 2008 Mar; 8(3):276-84. PubMed ID: 18336347
[TBL] [Abstract][Full Text] [Related]
26. A strategy for exploiting the pseudosymmetry of the C1-C13 stretch of discodermolide.
Parker KA; Katsoulis IA
Org Lett; 2004 Apr; 6(9):1413-6. PubMed ID: 15101755
[TBL] [Abstract][Full Text] [Related]
27. Short synthesis of the C1-C14 stretch of discodermolide from building blocks prepared by asymmetric catalysis.
Cao H; Parker KA
Org Lett; 2008 Apr; 10(7):1353-6. PubMed ID: 18311989
[TBL] [Abstract][Full Text] [Related]
28. Deconstruction-reconstruction strategy for accessing valuable polyketides. Preparation of the C15-C24 stereopentad of discodermolide.
Parker KA; Wang P
Org Lett; 2007 Nov; 9(23):4793-6. PubMed ID: 17924640
[TBL] [Abstract][Full Text] [Related]
29. Design and synthesis of (+)-discodermolide-paclitaxel hybrids leading to enhanced biological activity.
Smith AB; Sugasawa K; Atasoylu O; Yang CP; Horwitz SB
J Med Chem; 2011 Sep; 54(18):6319-27. PubMed ID: 21870795
[TBL] [Abstract][Full Text] [Related]
30. 1,6-asymmetric induction in boron-mediated aldol reactions: application to a practical total synthesis of (+)-discodermolide.
Paterson I; Delgado O; Florence GJ; Lyothier I; Scott JP; Sereinig N
Org Lett; 2003 Jan; 5(1):35-8. PubMed ID: 12509884
[TBL] [Abstract][Full Text] [Related]
31. Synthesis and biological assessment of simplified analogues of the potent microtubule stabilizer (+)-discodermolide.
Mínguez JM; Kim SY; Giuliano KA; Balachandran R; Madiraju C; Day BW; Curran DP
Bioorg Med Chem; 2003 Jul; 11(15):3335-57. PubMed ID: 12837544
[TBL] [Abstract][Full Text] [Related]
32. Discodermolide: just another microtubule-stabilizing agent? No! A lesson in synergy.
Giannakakou P; Fojo T
Clin Cancer Res; 2000 May; 6(5):1613-5. PubMed ID: 10815877
[No Abstract] [Full Text] [Related]
33. Total synthesis of (+)-discodermolide: a highly convergent fourth-generation approach.
Smith AB; Freeze BS; Xian M; Hirose T
Org Lett; 2005 Apr; 7(9):1825-8. PubMed ID: 15844916
[TBL] [Abstract][Full Text] [Related]
34. Discodermolide, a cytotoxic marine agent that stabilizes microtubules more potently than taxol.
ter Haar E; Kowalski RJ; Hamel E; Lin CM; Longley RE; Gunasekera SP; Rosenkranz HS; Day BW
Biochemistry; 1996 Jan; 35(1):243-50. PubMed ID: 8555181
[TBL] [Abstract][Full Text] [Related]
35. Total synthesis of (+)-discodermolide: an improved endgame exploiting a Still-Gennari-type olefination with a C1-C8 beta-ketophosphonate fragment.
Paterson I; Lyothier I
Org Lett; 2004 Dec; 6(26):4933-6. PubMed ID: 15606103
[TBL] [Abstract][Full Text] [Related]
36. Total synthesis of discodermolide: optimization of the effective synthetic route.
de Lemos E; Porée FH; Bourin A; Barbion J; Agouridas E; Lannou MI; Commerçon A; Betzer JF; Pancrazi A; Ardisson J
Chemistry; 2008; 14(35):11092-112. PubMed ID: 18973162
[TBL] [Abstract][Full Text] [Related]
37. Insights into the interaction of discodermolide and docetaxel with tubulin. Mapping the binding sites of microtubule-stabilizing agents by using an integrated NMR and computational approach.
Canales A; Rodríguez-Salarichs J; Trigili C; Nieto L; Coderch C; Andreu JM; Paterson I; Jiménez-Barbero J; Díaz JF
ACS Chem Biol; 2011 Aug; 6(8):789-99. PubMed ID: 21539341
[TBL] [Abstract][Full Text] [Related]
38. Designer discodermolide segments via ozonolysis of vinyl phosphonates.
Mollat du Jourdin X; Noshi M; Fuchs PL
Org Lett; 2009 Feb; 11(3):543-6. PubMed ID: 19117490
[TBL] [Abstract][Full Text] [Related]
39. Tubulin assembly, taxoid site binding, and cellular effects of the microtubule-stabilizing agent dictyostatin.
Madiraju C; Edler MC; Hamel E; Raccor BS; Balachandran R; Zhu G; Giuliano KA; Vogt A; Shin Y; Fournier JH; Fukui Y; Brückner AM; Curran DP; Day BW
Biochemistry; 2005 Nov; 44(45):15053-63. PubMed ID: 16274252
[TBL] [Abstract][Full Text] [Related]
40. Scalable, catalytic asymmetric synthesis of syn, anti stereotriad building blocks for polypropionate antibiotics.
Parker KA; Cao H
Org Lett; 2006 Aug; 8(16):3541-4. PubMed ID: 16869655
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]