333 related articles for article (PubMed ID: 15165132)
41. A convergent approach to cryptophycin 52 analogues: synthesis and biological evaluation of a novel series of fragment a epoxides and chlorohydrins.
Al-Awar RS; Ray JE; Schultz RM; Andis SL; Kennedy JH; Moore RE; Liang J; Golakoti T; Subbaraju GV; Corbett TH
J Med Chem; 2003 Jul; 46(14):2985-3007. PubMed ID: 12825938
[TBL] [Abstract][Full Text] [Related]
42. Chemistry. The renaissance of natural products as drug candidates.
Paterson I; Anderson EA
Science; 2005 Oct; 310(5747):451-3. PubMed ID: 16239465
[No Abstract] [Full Text] [Related]
43. Crotylsilane reagents in the synthesis of complex polyketide natural products: total synthesis of (+)-discodermolide.
Arefolov A; Panek JS
J Am Chem Soc; 2005 Apr; 127(15):5596-603. PubMed ID: 15826198
[TBL] [Abstract][Full Text] [Related]
44. Design, synthesis, and biological evaluation of potent discodermolide fluorescent and photoaffinity molecular probes.
Smith AB; Rucker PV; Brouard I; Freeze BS; Xia S; Horwitz SB
Org Lett; 2005 Nov; 7(23):5199-202. PubMed ID: 16268537
[TBL] [Abstract][Full Text] [Related]
45. alpha-Oxygenated crotyltitanium and dyotropic rearrangement in the total synthesis of discodermolide.
de Lemos E; Porée FH; Commerçon A; Betzer JF; Pancrazi A; Ardisson J
Angew Chem Int Ed Engl; 2007; 46(11):1917-21. PubMed ID: 17262876
[No Abstract] [Full Text] [Related]
46. Synergistic suppression of microtubule dynamics by discodermolide and paclitaxel in non-small cell lung carcinoma cells.
Honore S; Kamath K; Braguer D; Horwitz SB; Wilson L; Briand C; Jordan MA
Cancer Res; 2004 Jul; 64(14):4957-64. PubMed ID: 15256469
[TBL] [Abstract][Full Text] [Related]
47. Synthesis and biological study of a new series of 4'-demethylepipodophyllotoxin derivatives.
Duca M; Guianvarc'h D; Meresse P; Bertounesque E; Dauzonne D; Kraus-Berthier L; Thirot S; Léonce S; Pierré A; Pfeiffer B; Renard P; Arimondo PB; Monneret C
J Med Chem; 2005 Jan; 48(2):593-603. PubMed ID: 15658872
[TBL] [Abstract][Full Text] [Related]
48. Synthesis and antitumour activity of new muricatacin and goniofufurone analogues.
Popsavin V; Srećo B; Krstić I; Popsavin M; Kojić V; Bogdanović G
Eur J Med Chem; 2006 Oct; 41(10):1217-22. PubMed ID: 16891043
[TBL] [Abstract][Full Text] [Related]
49. Structure-activity relationship studies of discodermolide and its semisynthetic acetylated analogs on microtubule function and cytotoxicity.
Isbrucker RA; Gunasekera SP; Longley RE
Cancer Chemother Pharmacol; 2001 Jul; 48(1):29-36. PubMed ID: 11488521
[TBL] [Abstract][Full Text] [Related]
50. Design and synthesis of pironetin analogues with simplified structure and study of their interactions with microtubules.
Marco JA; García-Pla J; Carda M; Murga J; Falomir E; Trigili C; Notararigo S; Díaz JF; Barasoain I
Eur J Med Chem; 2011 May; 46(5):1630-7. PubMed ID: 21396747
[TBL] [Abstract][Full Text] [Related]
51. Decarboxylative Grob-type fragmentations in the synthesis of trisubstituted Z olefins: application to peloruside A, discodermolide, and epothilone D.
Prantz K; Mulzer J
Angew Chem Int Ed Engl; 2009; 48(27):5030-3. PubMed ID: 19492384
[TBL] [Abstract][Full Text] [Related]
52. Five new discodermolide analogues from the marine sponge Discodermia species.
Gunasekera SP; Paul GK; Longley RE; Isbrucker RA; Pomponi SA
J Nat Prod; 2002 Nov; 65(11):1643-8. PubMed ID: 12444691
[TBL] [Abstract][Full Text] [Related]
53. Formal synthesis of (+)-discodermolide.
Francavilla C; Chen W; Kinder FR
Org Lett; 2003 Apr; 5(8):1233-6. PubMed ID: 12688727
[TBL] [Abstract][Full Text] [Related]
54. The discodermolide hairpin structure flows from conformationally stable modular motifs.
Jogalekar AS; Kriel FH; Shi Q; Cornett B; Cicero D; Snyder JP
J Med Chem; 2010 Jan; 53(1):155-65. PubMed ID: 19894728
[TBL] [Abstract][Full Text] [Related]
55. Development of a third-generation total synthesis of (+)-discodermolide: an expedient Still-Gennari-type fragment coupling utilizing an advanced beta-ketophosphonate.
Paterson I; Lyothier I
J Org Chem; 2005 Jul; 70(14):5494-507. PubMed ID: 15989331
[TBL] [Abstract][Full Text] [Related]
56. Distinct pose of discodermolide in taxol binding pocket drives a complementary mode of microtubule stabilization.
Khrapunovich-Baine M; Menon V; Verdier-Pinard P; Smith AB; Angeletti RH; Fiser A; Horwitz SB; Xiao H
Biochemistry; 2009 Dec; 48(49):11664-77. PubMed ID: 19863156
[TBL] [Abstract][Full Text] [Related]
57. Novel cryptophycin antitumor agents: synthesis and cytotoxicity of fragment "B" analogues.
Patel VF; Andis SL; Kennedy JH; Ray JE; Schultz RM
J Med Chem; 1999 Jul; 42(14):2588-603. PubMed ID: 10411479
[TBL] [Abstract][Full Text] [Related]
58. Regulated-stereoselective construction of thirteen stereogenic centers necessary for the frame of (+)-discodermolide, based on iterative Lewis acid-promoted aldol reactions.
Kiyooka S; Shahid KA; Goto F; Okazaki M; Shuto Y
J Org Chem; 2003 Oct; 68(21):7967-78. PubMed ID: 14535772
[TBL] [Abstract][Full Text] [Related]
59. Synthesis and high content cell-based profiling of simplified analogues of the microtubule stabilizer (+)-discodermolide.
Minguez JM; Giuliano KA; Balachandran R; Madiraju C; Curran DP; Day BW
Mol Cancer Ther; 2002 Dec; 1(14):1305-13. PubMed ID: 12516963
[TBL] [Abstract][Full Text] [Related]
60. The relationship between Taxol and (+)-discodermolide: synthetic analogs and modeling studies.
Martello LA; LaMarche MJ; He L; Beauchamp TJ; Smith AB; Horwitz SB
Chem Biol; 2001 Sep; 8(9):843-55. PubMed ID: 11564553
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
