BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

235 related articles for article (PubMed ID: 15166217)

  • 1. Ubiquitination and proteasomal degradation of the BRCA1 tumor suppressor is regulated during cell cycle progression.
    Choudhury AD; Xu H; Baer R
    J Biol Chem; 2004 Aug; 279(32):33909-18. PubMed ID: 15166217
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The UBXN1 protein associates with autoubiquitinated forms of the BRCA1 tumor suppressor and inhibits its enzymatic function.
    Wu-Baer F; Ludwig T; Baer R
    Mol Cell Biol; 2010 Jun; 30(11):2787-98. PubMed ID: 20351172
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Down-regulation of BRCA1-BARD1 ubiquitin ligase by CDK2.
    Hayami R; Sato K; Wu W; Nishikawa T; Hiroi J; Ohtani-Kaneko R; Fukuda M; Ohta T
    Cancer Res; 2005 Jan; 65(1):6-10. PubMed ID: 15665273
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Mass spectrometric and mutational analyses reveal Lys-6-linked polyubiquitin chains catalyzed by BRCA1-BARD1 ubiquitin ligase.
    Nishikawa H; Ooka S; Sato K; Arima K; Okamoto J; Klevit RE; Fukuda M; Ohta T
    J Biol Chem; 2004 Feb; 279(6):3916-24. PubMed ID: 14638690
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Proteasome-mediated degradation of BRCA1 protein in MCF-7 human breast cancer cells.
    Choi YH
    Int J Oncol; 2001 Oct; 19(4):687-93. PubMed ID: 11562742
    [TBL] [Abstract][Full Text] [Related]  

  • 6. BRCA1-associated protein 1 interferes with BRCA1/BARD1 RING heterodimer activity.
    Nishikawa H; Wu W; Koike A; Kojima R; Gomi H; Fukuda M; Ohta T
    Cancer Res; 2009 Jan; 69(1):111-9. PubMed ID: 19117993
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Nucleophosmin/B23 is a candidate substrate for the BRCA1-BARD1 ubiquitin ligase.
    Sato K; Hayami R; Wu W; Nishikawa T; Nishikawa H; Okuda Y; Ogata H; Fukuda M; Ohta T
    J Biol Chem; 2004 Jul; 279(30):30919-22. PubMed ID: 15184379
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The BRCA1/BARD1 heterodimer assembles polyubiquitin chains through an unconventional linkage involving lysine residue K6 of ubiquitin.
    Wu-Baer F; Lagrazon K; Yuan W; Baer R
    J Biol Chem; 2003 Sep; 278(37):34743-6. PubMed ID: 12890688
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Autoubiquitination of the BRCA1*BARD1 RING ubiquitin ligase.
    Chen A; Kleiman FE; Manley JL; Ouchi T; Pan ZQ
    J Biol Chem; 2002 Jun; 277(24):22085-92. PubMed ID: 11927591
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Kip1 degradation via the ubiquitin-proteasome pathway.
    Tam SW; Theodoras AM; Pagano M
    Leukemia; 1997 Apr; 11 Suppl 3():363-6. PubMed ID: 9209391
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Cell cycle-dependent colocalization of BARD1 and BRCA1 proteins in discrete nuclear domains.
    Jin Y; Xu XL; Yang MC; Wei F; Ayi TC; Bowcock AM; Baer R
    Proc Natl Acad Sci U S A; 1997 Oct; 94(22):12075-80. PubMed ID: 9342365
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Identification of domains of BRCA1 critical for the ubiquitin-dependent inhibition of centrosome function.
    Sankaran S; Starita LM; Simons AM; Parvin JD
    Cancer Res; 2006 Apr; 66(8):4100-7. PubMed ID: 16618730
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Ubiquitination and proteasome-mediated degradation of BRCA1 and BARD1 during steroidogenesis in human ovarian granulosa cells.
    Lu Y; Amleh A; Sun J; Jin X; McCullough SD; Baer R; Ren D; Li R; Hu Y
    Mol Endocrinol; 2007 Mar; 21(3):651-63. PubMed ID: 17185394
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Degradation of transcription repressor ZBRK1 through the ubiquitin-proteasome pathway relieves repression of Gadd45a upon DNA damage.
    Yun J; Lee WH
    Mol Cell Biol; 2003 Oct; 23(20):7305-14. PubMed ID: 14517299
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Nuclear targeting and cell cycle regulatory function of human BARD1.
    Schüchner S; Tembe V; Rodriguez JA; Henderson BR
    J Biol Chem; 2005 Mar; 280(10):8855-61. PubMed ID: 15632137
    [TBL] [Abstract][Full Text] [Related]  

  • 16. BRCA1 : BARD1 induces the formation of conjugated ubiquitin structures, dependent on K6 of ubiquitin, in cells during DNA replication and repair.
    Morris JR; Solomon E
    Hum Mol Genet; 2004 Apr; 13(8):807-17. PubMed ID: 14976165
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The ubiquitin-proteasome pathway regulates survivin degradation in a cell cycle-dependent manner.
    Zhao J; Tenev T; Martins LM; Downward J; Lemoine NR
    J Cell Sci; 2000 Dec; 113 Pt 23():4363-71. PubMed ID: 11069780
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The BRCA1/BARD1 ubiquitin ligase and its substrates.
    Witus SR; Stewart MD; Klevit RE
    Biochem J; 2021 Sep; 478(18):3467-3483. PubMed ID: 34591954
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Mdm-2 and ubiquitin-independent p53 proteasomal degradation regulated by NQO1.
    Asher G; Lotem J; Sachs L; Kahana C; Shaul Y
    Proc Natl Acad Sci U S A; 2002 Oct; 99(20):13125-30. PubMed ID: 12232053
    [TBL] [Abstract][Full Text] [Related]  

  • 20. HERC2 is an E3 ligase that targets BRCA1 for degradation.
    Wu W; Sato K; Koike A; Nishikawa H; Koizumi H; Venkitaraman AR; Ohta T
    Cancer Res; 2010 Aug; 70(15):6384-92. PubMed ID: 20631078
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.