BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

581 related articles for article (PubMed ID: 15169911)

  • 1. Impaired alveologenesis and maintenance of secretory mammary epithelial cells in Jak2 conditional knockout mice.
    Wagner KU; Krempler A; Triplett AA; Qi Y; George NM; Zhu J; Rui H
    Mol Cell Biol; 2004 Jun; 24(12):5510-20. PubMed ID: 15169911
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Jak2 is an essential tyrosine kinase involved in pregnancy-mediated development of mammary secretory epithelium.
    Shillingford JM; Miyoshi K; Robinson GW; Grimm SL; Rosen JM; Neubauer H; Pfeffer K; Hennighausen L
    Mol Endocrinol; 2002 Mar; 16(3):563-70. PubMed ID: 11875116
    [TBL] [Abstract][Full Text] [Related]  

  • 3. PRL-induced ERalpha gene expression is mediated by Janus kinase 2 (Jak2) while signal transducer and activator of transcription 5b (Stat5b) phosphorylation involves Jak2 and a second tyrosine kinase.
    Frasor J; Barkai U; Zhong L; Fazleabas AT; Gibori G
    Mol Endocrinol; 2001 Nov; 15(11):1941-52. PubMed ID: 11682625
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Janus kinase 2 (JAK2) regulates prolactin-mediated chloride transport in mouse mammary epithelial cells through tyrosine phosphorylation of Na+-K+-2Cl- cotransporter.
    Selvaraj NG; Omi E; Gibori G; Rao MC
    Mol Endocrinol; 2000 Dec; 14(12):2054-65. PubMed ID: 11117534
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Caveolin-1-deficient mice show accelerated mammary gland development during pregnancy, premature lactation, and hyperactivation of the Jak-2/STAT5a signaling cascade.
    Park DS; Lee H; Frank PG; Razani B; Nguyen AV; Parlow AF; Russell RG; Hulit J; Pestell RG; Lisanti MP
    Mol Biol Cell; 2002 Oct; 13(10):3416-30. PubMed ID: 12388746
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Prolactin, growth hormone, and epidermal growth factor activate Stat5 in different compartments of mammary tissue and exert different and overlapping developmental effects.
    Gallego MI; Binart N; Robinson GW; Okagaki R; Coschigano KT; Perry J; Kopchick JJ; Oka T; Kelly PA; Hennighausen L
    Dev Biol; 2001 Jan; 229(1):163-75. PubMed ID: 11133161
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Cloning and expression of Stat5 and an additional homologue (Stat5b) involved in prolactin signal transduction in mouse mammary tissue.
    Liu X; Robinson GW; Gouilleux F; Groner B; Hennighausen L
    Proc Natl Acad Sci U S A; 1995 Sep; 92(19):8831-5. PubMed ID: 7568026
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Inactivation of Stat5 in mouse mammary epithelium during pregnancy reveals distinct functions in cell proliferation, survival, and differentiation.
    Cui Y; Riedlinger G; Miyoshi K; Tang W; Li C; Deng CX; Robinson GW; Hennighausen L
    Mol Cell Biol; 2004 Sep; 24(18):8037-47. PubMed ID: 15340066
    [TBL] [Abstract][Full Text] [Related]  

  • 9. A cytosolic protein-tyrosine phosphatase PTP1B specifically dephosphorylates and deactivates prolactin-activated STAT5a and STAT5b.
    Aoki N; Matsuda T
    J Biol Chem; 2000 Dec; 275(50):39718-26. PubMed ID: 10993888
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Basal activation of transcription factor signal transducer and activator of transcription (Stat5) in nonpregnant mouse and human breast epithelium.
    Nevalainen MT; Xie J; Bubendorf L; Wagner KU; Rui H
    Mol Endocrinol; 2002 May; 16(5):1108-24. PubMed ID: 11981045
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Dominant negative variants of the SHP-2 tyrosine phosphatase inhibit prolactin activation of Jak2 (janus kinase 2) and induction of Stat5 (signal transducer and activator of transcription 5)-dependent transcription.
    Berchtold S; Volarevic S; Moriggl R; Mercep M; Groner B
    Mol Endocrinol; 1998 Apr; 12(4):556-67. PubMed ID: 9544991
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Role of tyrosine kinase Jak2 in prolactin-induced differentiation and growth of mammary epithelial cells.
    Xie J; LeBaron MJ; Nevalainen MT; Rui H
    J Biol Chem; 2002 Apr; 277(16):14020-30. PubMed ID: 11821424
    [TBL] [Abstract][Full Text] [Related]  

  • 13. JAK2 and STAT5, but not JAK1 and STAT1, are required for prolactin-induced beta-lactoglobulin transcription.
    Han Y; Watling D; Rogers NC; Stark GR
    Mol Endocrinol; 1997 Jul; 11(8):1180-8. PubMed ID: 9212064
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Interactions among Janus kinases and the prolactin (PRL) receptor in the regulation of a PRL response element.
    Gao J; Hughes JP; Auperin B; Buteau H; Edery M; Zhuang H; Wojchowski DM; Horseman ND
    Mol Endocrinol; 1996 Jul; 10(7):847-56. PubMed ID: 8813725
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Expression of functional prolactin receptors in nonpregnant human endometrium: janus kinase-2, signal transducer and activator of transcription-1 (STAT1), and STAT5 proteins are phosphorylated after stimulation with prolactin.
    Jabbour HN; Critchley HO; Boddy SC
    J Clin Endocrinol Metab; 1998 Jul; 83(7):2545-53. PubMed ID: 9661641
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Impaired differentiation and lactational failure of Erbb4-deficient mammary glands identify ERBB4 as an obligate mediator of STAT5.
    Long W; Wagner KU; Lloyd KC; Binart N; Shillingford JM; Hennighausen L; Jones FE
    Development; 2003 Nov; 130(21):5257-68. PubMed ID: 12954715
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Functional rescue of Stat5a-null mammary tissue through the activation of compensating signals including Stat5b.
    Liu X; Gallego MI; Smith GH; Robinson GW; Hennighausen L
    Cell Growth Differ; 1998 Sep; 9(9):795-803. PubMed ID: 9751123
    [TBL] [Abstract][Full Text] [Related]  

  • 18. An immunohistochemical approach to monitor the prolactin-induced activation of the JAK2/STAT5 pathway in pancreatic islets of Langerhans.
    Brelje TC; Svensson AM; Stout LE; Bhagroo NV; Sorenson RL
    J Histochem Cytochem; 2002 Mar; 50(3):365-83. PubMed ID: 11850439
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Prolactin signal transduction to milk protein genes: carboxy-terminal part of the prolactin receptor and its tyrosine phosphorylation are not obligatory for JAK2 and STAT5 activation.
    Goupille O; Daniel N; Bignon C; Jolivet G; Djiane J
    Mol Cell Endocrinol; 1997 Mar; 127(2):155-69. PubMed ID: 9099911
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Receptor activator of NF-kappaB ligand induction via Jak2 and Stat5a in mammary epithelial cells.
    Srivastava S; Matsuda M; Hou Z; Bailey JP; Kitazawa R; Herbst MP; Horseman ND
    J Biol Chem; 2003 Nov; 278(46):46171-8. PubMed ID: 12952963
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 30.