388 related articles for article (PubMed ID: 15170323)
1. Serine hydroxymethyltransferase: role of glu75 and evidence that serine is cleaved by a retroaldol mechanism.
Szebenyi DM; Musayev FN; di Salvo ML; Safo MK; Schirch V
Biochemistry; 2004 Jun; 43(22):6865-76. PubMed ID: 15170323
[TBL] [Abstract][Full Text] [Related]
2. Serine hydroxymethyltransferase revisited.
Schirch V; Szebenyi DM
Curr Opin Chem Biol; 2005 Oct; 9(5):482-7. PubMed ID: 16125438
[TBL] [Abstract][Full Text] [Related]
3. Structure determination and biochemical studies on Bacillus stearothermophilus E53Q serine hydroxymethyltransferase and its complexes provide insights on function and enzyme memory.
Rajaram V; Bhavani BS; Kaul P; Prakash V; Appaji Rao N; Savithri HS; Murthy MR
FEBS J; 2007 Aug; 274(16):4148-60. PubMed ID: 17651438
[TBL] [Abstract][Full Text] [Related]
4. Crystal structure of rabbit cytosolic serine hydroxymethyltransferase at 2.8 A resolution: mechanistic implications.
Scarsdale JN; Kazanina G; Radaev S; Schirch V; Wright HT
Biochemistry; 1999 Jun; 38(26):8347-58. PubMed ID: 10387080
[TBL] [Abstract][Full Text] [Related]
5. Crystal structure at 2.4 A resolution of E. coli serine hydroxymethyltransferase in complex with glycine substrate and 5-formyl tetrahydrofolate.
Scarsdale JN; Radaev S; Kazanina G; Schirch V; Wright HT
J Mol Biol; 2000 Feb; 296(1):155-68. PubMed ID: 10656824
[TBL] [Abstract][Full Text] [Related]
6. Serine hydroxymethyltransferase isoforms are differentially inhibited by leucovorin: characterization and comparison of recombinant zebrafish serine hydroxymethyltransferases.
Chang WN; Tsai JN; Chen BH; Huang HS; Fu TF
Drug Metab Dispos; 2007 Nov; 35(11):2127-37. PubMed ID: 17664250
[TBL] [Abstract][Full Text] [Related]
7. Structure of a murine cytoplasmic serine hydroxymethyltransferase quinonoid ternary complex: evidence for asymmetric obligate dimers.
Szebenyi DM; Liu X; Kriksunov IA; Stover PJ; Thiel DJ
Biochemistry; 2000 Nov; 39(44):13313-23. PubMed ID: 11063567
[TBL] [Abstract][Full Text] [Related]
8. Properties of human and rabbit cytosolic serine hydroxymethyltransferase are changed by single nucleotide polymorphic mutations.
Fu TF; Hunt S; Schirch V; Safo MK; Chen BH
Arch Biochem Biophys; 2005 Oct; 442(1):92-101. PubMed ID: 16137637
[TBL] [Abstract][Full Text] [Related]
9. Role of tyrosine 65 in the mechanism of serine hydroxymethyltransferase.
Contestabile R; Angelaccio S; Bossa F; Wright HT; Scarsdale N; Kazanina G; Schirch V
Biochemistry; 2000 Jun; 39(25):7492-500. PubMed ID: 10858298
[TBL] [Abstract][Full Text] [Related]
10. Crystal structure of binary and ternary complexes of serine hydroxymethyltransferase from Bacillus stearothermophilus: insights into the catalytic mechanism.
Trivedi V; Gupta A; Jala VR; Saravanan P; Rao GS; Rao NA; Savithri HS; Subramanya HS
J Biol Chem; 2002 May; 277(19):17161-9. PubMed ID: 11877399
[TBL] [Abstract][Full Text] [Related]
11. The role of Glu74 and Tyr82 in the reaction catalyzed by sheep liver cytosolic serine hydroxymethyltransferase.
Rao JV; Prakash V; Rao NA; Savithri HS
Eur J Biochem; 2000 Oct; 267(19):5967-76. PubMed ID: 10998057
[TBL] [Abstract][Full Text] [Related]
12. In silico and in vitro validation of serine hydroxymethyltransferase as a chemotherapeutic target of the antifolate drug pemetrexed.
Daidone F; Florio R; Rinaldo S; Contestabile R; di Salvo ML; CutruzzolĂ F; Bossa F; Paiardini A
Eur J Med Chem; 2011 May; 46(5):1616-21. PubMed ID: 21371789
[TBL] [Abstract][Full Text] [Related]
13. Importance of tyrosine residues of Bacillus stearothermophilus serine hydroxymethyltransferase in cofactor binding and L-allo-Thr cleavage.
Bhavani BS; Rajaram V; Bisht S; Kaul P; Prakash V; Murthy MR; Appaji Rao N; Savithri HS
FEBS J; 2008 Sep; 275(18):4606-19. PubMed ID: 18699779
[TBL] [Abstract][Full Text] [Related]
14. The crystal structure of human cytosolic serine hydroxymethyltransferase: a target for cancer chemotherapy.
Renwick SB; Snell K; Baumann U
Structure; 1998 Sep; 6(9):1105-16. PubMed ID: 9753690
[TBL] [Abstract][Full Text] [Related]
15. Is mutated serine hydroxymethyltransferase (SHMT) involved in the etiology of neural tube defects?
Heil SG; Van der Put NM; Waas ET; den Heijer M; Trijbels FJ; Blom HJ
Mol Genet Metab; 2001 Jun; 73(2):164-72. PubMed ID: 11386852
[TBL] [Abstract][Full Text] [Related]
16. Structure-function relationship in serine hydroxymethyltransferase.
Appaji Rao N; Ambili M; Jala VR; Subramanya HS; Savithri HS
Biochim Biophys Acta; 2003 Apr; 1647(1-2):24-9. PubMed ID: 12686103
[TBL] [Abstract][Full Text] [Related]
17. Serine hydroxymethyltransferase catalyzes the hydrolysis of 5,10-methenyltetrahydrofolate to 5-formyltetrahydrofolate.
Stover P; Schirch V
J Biol Chem; 1990 Aug; 265(24):14227-33. PubMed ID: 2201683
[TBL] [Abstract][Full Text] [Related]
18. 5-Formyltetrahydrofolate is an inhibitory but well tolerated metabolite in Arabidopsis leaves.
Goyer A; Collakova E; DĂaz de la Garza R; Quinlivan EP; Williamson J; Gregory JF; Shachar-Hill Y; Hanson AD
J Biol Chem; 2005 Jul; 280(28):26137-42. PubMed ID: 15888445
[TBL] [Abstract][Full Text] [Related]
19. Crystal structure of human T-protein of glycine cleavage system at 2.0 A resolution and its implication for understanding non-ketotic hyperglycinemia.
Okamura-Ikeda K; Hosaka H; Yoshimura M; Yamashita E; Toma S; Nakagawa A; Fujiwara K; Motokawa Y; Taniguchi H
J Mol Biol; 2005 Sep; 351(5):1146-59. PubMed ID: 16051266
[TBL] [Abstract][Full Text] [Related]
20. Serine hydroxymethyltransferase from Plasmodium vivax is different in substrate specificity from its homologues.
Sopitthummakhun K; Maenpuen S; Yuthavong Y; Leartsakulpanich U; Chaiyen P
FEBS J; 2009 Aug; 276(15):4023-36. PubMed ID: 19549189
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]