BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

427 related articles for article (PubMed ID: 15173171)

  • 1. Structures of human cytosolic NADP-dependent isocitrate dehydrogenase reveal a novel self-regulatory mechanism of activity.
    Xu X; Zhao J; Xu Z; Peng B; Huang Q; Arnold E; Ding J
    J Biol Chem; 2004 Aug; 279(32):33946-57. PubMed ID: 15173171
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Structural studies of Saccharomyces cerevesiae mitochondrial NADP-dependent isocitrate dehydrogenase in different enzymatic states reveal substantial conformational changes during the catalytic reaction.
    Peng Y; Zhong C; Huang W; Ding J
    Protein Sci; 2008 Sep; 17(9):1542-54. PubMed ID: 18552125
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Crystal structures of NAD
    Tang W; Wu M; Qin N; Liu L; Meng R; Wang C; Wang P; Zang J; Zhu G
    Arch Biochem Biophys; 2021 Sep; 708():108898. PubMed ID: 33957092
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Substrate-free structure of a monomeric NADP isocitrate dehydrogenase: an open conformation phylogenetic relationship of isocitrate dehydrogenase.
    Imabayashi F; Aich S; Prasad L; Delbaere LT
    Proteins; 2006 Apr; 63(1):100-12. PubMed ID: 16416443
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Crystal structure of the monomeric isocitrate dehydrogenase in the presence of NADP+: insight into the cofactor recognition, catalysis, and evolution.
    Yasutake Y; Watanabe S; Yao M; Takada Y; Fukunaga N; Tanaka I
    J Biol Chem; 2003 Sep; 278(38):36897-904. PubMed ID: 12855708
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Two phylogenetically divergent isocitrate dehydrogenases are encoded in Leishmania parasites. Molecular and functional characterization of Leishmania mexicana isoenzymes with specificity towards NAD
    Giordana L; Nowicki C
    Mol Biochem Parasitol; 2020 Nov; 240():111320. PubMed ID: 32980452
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Expression, purification, and crystallization of type 1 isocitrate dehydrogenase from Trypanosoma brucei brucei.
    Wang X; Inaoka DK; Shiba T; Balogun EO; Allmann S; Watanabe YI; Boshart M; Kita K; Harada S
    Protein Expr Purif; 2017 Oct; 138():56-62. PubMed ID: 28642005
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Isocitrate dehydrogenase from the hyperthermophile Aeropyrum pernix: X-ray structure analysis of a ternary enzyme-substrate complex and thermal stability.
    Karlström M; Stokke R; Steen IH; Birkeland NK; Ladenstein R
    J Mol Biol; 2005 Jan; 345(3):559-77. PubMed ID: 15581899
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Crystal structure of porcine mitochondrial NADP+-dependent isocitrate dehydrogenase complexed with Mn2+ and isocitrate. Insights into the enzyme mechanism.
    Ceccarelli C; Grodsky NB; Ariyaratne N; Colman RF; Bahnson BJ
    J Biol Chem; 2002 Nov; 277(45):43454-62. PubMed ID: 12207025
    [TBL] [Abstract][Full Text] [Related]  

  • 10. A unique homodimeric NAD⁺-linked isocitrate dehydrogenase from the smallest autotrophic eukaryote Ostreococcus tauri.
    Tang WG; Song P; Cao ZY; Wang P; Zhu GP
    FASEB J; 2015 Jun; 29(6):2462-72. PubMed ID: 25724193
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A Novel Type II NAD+-Specific Isocitrate Dehydrogenase from the Marine Bacterium Congregibacter litoralis KT71.
    Wu MC; Tian CQ; Cheng HM; Xu L; Wang P; Zhu GP
    PLoS One; 2015; 10(5):e0125229. PubMed ID: 25942017
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Structural basis for a change in substrate specificity: crystal structure of S113E isocitrate dehydrogenase in a complex with isopropylmalate, Mg2+, and NADP.
    Doyle SA; Beernink PT; Koshland DE
    Biochemistry; 2001 Apr; 40(14):4234-41. PubMed ID: 11284679
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Functional characterization of NADP-dependent isocitrate dehydrogenase isozymes from Trypanosoma cruzi.
    Leroux AE; Maugeri DA; Cazzulo JJ; Nowicki C
    Mol Biochem Parasitol; 2011 May; 177(1):61-4. PubMed ID: 21291916
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Structural and functional properties of isocitrate dehydrogenase from the psychrophilic bacterium Desulfotalea psychrophila reveal a cold-active enzyme with an unusual high thermal stability.
    Fedøy AE; Yang N; Martinez A; Leiros HK; Steen IH
    J Mol Biol; 2007 Sep; 372(1):130-49. PubMed ID: 17632124
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Single arginine mutation in two yeast isocitrate dehydrogenases: biochemical characterization and functional implication.
    Song P; Wei H; Cao Z; Wang P; Zhu G
    PLoS One; 2014; 9(12):e115025. PubMed ID: 25502799
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Biochemical and molecular characterization of the isocitrate dehydrogenase with dual coenzyme specificity from the obligate methylotroph Methylobacillus Flagellatus.
    Romkina AY; Kiriukhin MY
    PLoS One; 2017; 12(4):e0176056. PubMed ID: 28423051
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Location of the coenzyme binding site in the porcine mitochondrial NADP-dependent isocitrate dehydrogenase.
    Huang YC; Colman RF
    J Biol Chem; 2005 Aug; 280(34):30349-53. PubMed ID: 15975917
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Structure of the monomeric isocitrate dehydrogenase: evidence of a protein monomerization by a domain duplication.
    Yasutake Y; Watanabe S; Yao M; Takada Y; Fukunaga N; Tanaka I
    Structure; 2002 Dec; 10(12):1637-48. PubMed ID: 12467571
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Evaluation by mutagenesis of the roles of His309, His315, and His319 in the coenzyme site of pig heart NADP-dependent isocitrate dehydrogenase.
    Huang YC; Colman RF
    Biochemistry; 2002 Apr; 41(17):5637-43. PubMed ID: 11969425
    [TBL] [Abstract][Full Text] [Related]  

  • 20. From a dimer to a monomer: Construction of a chimeric monomeric isocitrate dehydrogenase.
    Tian C; Wen B; Bian M; Jin M; Wang P; Xu L; Zhu G
    Protein Sci; 2021 Dec; 30(12):2396-2407. PubMed ID: 34647384
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 22.