104 related articles for article (PubMed ID: 15174175)
1. Biosynthesis of carbapenem antibiotics: new carbapenam substrates for carbapenem synthase (CarC).
Sleeman MC; Smith P; Kellam B; Chhabra SR; Bycroft BW; Schofield CJ
Chembiochem; 2004 Jun; 5(6):879-82. PubMed ID: 15174175
[No Abstract] [Full Text] [Related]
2. Carbapenem biosynthesis: confirmation of stereochemical assignments and the role of CarC in the ring stereoinversion process from L-proline.
Stapon A; Li R; Townsend CA
J Am Chem Soc; 2003 Jul; 125(28):8486-93. PubMed ID: 12848554
[TBL] [Abstract][Full Text] [Related]
3. Synthesis of (3S,5R)-carbapenam-3-carboxylic acid and its role in carbapenem biosynthesis and the stereoinversion problem.
Stapon A; Li R; Townsend CA
J Am Chem Soc; 2003 Dec; 125(51):15746-7. PubMed ID: 14677956
[TBL] [Abstract][Full Text] [Related]
4. Regulation and biosynthesis of carbapenem antibiotics in bacteria.
Coulthurst SJ; Barnard AM; Salmond GP
Nat Rev Microbiol; 2005 Apr; 3(4):295-306. PubMed ID: 15759042
[TBL] [Abstract][Full Text] [Related]
5. Crystal structure of carbapenem synthase (CarC).
Clifton IJ; Doan LX; Sleeman MC; Topf M; Suzuki H; Wilmouth RC; Schofield CJ
J Biol Chem; 2003 Jun; 278(23):20843-50. PubMed ID: 12611886
[TBL] [Abstract][Full Text] [Related]
6. Non-heme iron oxygenases generate natural structural diversity in carbapenem antibiotics.
Bodner MJ; Phelan RM; Freeman MF; Li R; Townsend CA
J Am Chem Soc; 2010 Jan; 132(1):12-3. PubMed ID: 20017478
[TBL] [Abstract][Full Text] [Related]
7. Methylations in complex carbapenem biosynthesis are catalyzed by a single cobalamin-dependent radical S-adenosylmethionine enzyme.
Sinner EK; Lichstrahl MS; Li R; Marous DR; Townsend CA
Chem Commun (Camb); 2019 Dec; 55(99):14934-14937. PubMed ID: 31774078
[TBL] [Abstract][Full Text] [Related]
8. Inhibition and alternate substrate studies on the mechanism of carbapenam synthetase from Erwinia carotovora.
Gerratana B; Stapon A; Townsend CA
Biochemistry; 2003 Jul; 42(25):7836-47. PubMed ID: 12820893
[TBL] [Abstract][Full Text] [Related]
9. The unusual bifunctional catalysis of epimerization and desaturation by carbapenem synthase.
Topf M; Sandala GM; Smith DM; Schofield CJ; Easton CJ; Radom L
J Am Chem Soc; 2004 Aug; 126(32):9932-3. PubMed ID: 15303862
[TBL] [Abstract][Full Text] [Related]
10. Synthesis of deuterium labelled L- and D-glutamate semialdehydes and their evaluation as substrates for carboxymethylproline synthase (CarB)--implications for carbapenem biosynthesis.
Sorensen JL; Sleeman MC; Schofield CJ
Chem Commun (Camb); 2005 Mar; (9):1155-7. PubMed ID: 15726176
[TBL] [Abstract][Full Text] [Related]
11. Mechanism of the C5 stereoinversion reaction in the biosynthesis of carbapenem antibiotics.
Chang WC; Guo Y; Wang C; Butch SE; Rosenzweig AC; Boal AK; Krebs C; Bollinger JM
Science; 2014 Mar; 343(6175):1140-4. PubMed ID: 24604200
[TBL] [Abstract][Full Text] [Related]
12. Crotonase catalysis enables flexible production of functionalized prolines and carbapenams.
Hamed RB; Henry L; Gomez-Castellanos JR; Mecinović J; Ducho C; Sorensen JL; Claridge TD; Schofield CJ
J Am Chem Soc; 2012 Jan; 134(1):471-9. PubMed ID: 22091817
[TBL] [Abstract][Full Text] [Related]
13. Carbapenem-based prodrugs. Design, synthesis, and biological evaluation of carbapenems.
Hakimelahi GH; Moosavi-Movahedi AA; Saboury AA; Osetrov V; Khodarahmi GA; Shia KS
Eur J Med Chem; 2005 Apr; 40(4):339-49. PubMed ID: 15804533
[TBL] [Abstract][Full Text] [Related]
14. The biosynthetic implications of acetate and glutamate incorporation into (3R,5R)-carbapenam-3-carboxylic acid and (5R)-carbapen-2-em-3-carboxylic acid by Serratia sp.
Bycroft BW; Maslen C; Box SJ; Brown A; Tyler JW
J Antibiot (Tokyo); 1988 Sep; 41(9):1231-42. PubMed ID: 3182403
[TBL] [Abstract][Full Text] [Related]
15. CP5484, a novel quaternary carbapenem with potent anti-MRSA activity and reduced toxicity.
Maruyama T; Yamamoto Y; Kano Y; Kurazono M; Matsuhisa E; Takata H; Takata T; Atsumi K; Iwamatsu K; Shitara E
Bioorg Med Chem; 2007 Oct; 15(19):6379-87. PubMed ID: 17681767
[TBL] [Abstract][Full Text] [Related]
16. Synthesis of novel di- and tricationic carbapenems with potent anti-MRSA activity.
Maruyama T; Yamamoto Y; Kano Y; Kurazono M; Shitara E; Iwamatsu K; Atsumi K
Bioorg Med Chem Lett; 2009 Jan; 19(2):447-50. PubMed ID: 19056265
[TBL] [Abstract][Full Text] [Related]
17. Biosynthesis of tripyrrole and beta-lactam secondary metabolites in Serratia: integration of quorum sensing with multiple new regulatory components in the control of prodigiosin and carbapenem antibiotic production.
Fineran PC; Slater H; Everson L; Hughes K; Salmond GP
Mol Microbiol; 2005 Jun; 56(6):1495-517. PubMed ID: 15916601
[TBL] [Abstract][Full Text] [Related]
18. SME-3, a novel member of the Serratia marcescens SME family of carbapenem-hydrolyzing beta-lactamases.
Queenan AM; Shang W; Schreckenberger P; Lolans K; Bush K; Quinn J
Antimicrob Agents Chemother; 2006 Oct; 50(10):3485-7. PubMed ID: 17005839
[TBL] [Abstract][Full Text] [Related]
19. Synthesis and SAR study of novel 7-(pyridinium-3-yl)-carbonyl imidazo[5,1-b]thiazol-2-yl carbapenems.
Maruyama T; Kano Y; Yamamoto Y; Kurazono M; Iwamatsu K; Atsumi K; Shitara E
Bioorg Med Chem; 2007 Jan; 15(1):392-402. PubMed ID: 17055731
[TBL] [Abstract][Full Text] [Related]
20. A theoretical proposal for the synthesis of carbapenems from 4-(2-propynyl)azetidinones promoted by [W(CO)5] as an alternative to the Ag+-assisted process.
Campomanes P; Menéndez MI; Sordo TL
Chemistry; 2006 Oct; 12(30):7929-34. PubMed ID: 16871499
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
