BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

294 related articles for article (PubMed ID: 15175264)

  • 1. Mismatch repair-dependent G2 checkpoint induced by low doses of SN1 type methylating agents requires the ATR kinase.
    Stojic L; Mojas N; Cejka P; Di Pietro M; Ferrari S; Marra G; Jiricny J
    Genes Dev; 2004 Jun; 18(11):1331-44. PubMed ID: 15175264
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Methylator-induced, mismatch repair-dependent G2 arrest is activated through Chk1 and Chk2.
    Adamson AW; Beardsley DI; Kim WJ; Gao Y; Baskaran R; Brown KD
    Mol Biol Cell; 2005 Mar; 16(3):1513-26. PubMed ID: 15647386
    [TBL] [Abstract][Full Text] [Related]  

  • 3. CHK1 and CHK2 are differentially involved in mismatch repair-mediated 6-thioguanine-induced cell cycle checkpoint responses.
    Yan T; Desai AB; Jacobberger JW; Sramkoski RM; Loh T; Kinsella TJ
    Mol Cancer Ther; 2004 Sep; 3(9):1147-57. PubMed ID: 15367709
    [TBL] [Abstract][Full Text] [Related]  

  • 4. DNA damage induced by temozolomide signals to both ATM and ATR: role of the mismatch repair system.
    Caporali S; Falcinelli S; Starace G; Russo MT; Bonmassar E; Jiricny J; D'Atri S
    Mol Pharmacol; 2004 Sep; 66(3):478-91. PubMed ID: 15322239
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Inhibition of human Chk1 causes increased initiation of DNA replication, phosphorylation of ATR targets, and DNA breakage.
    Syljuåsen RG; Sørensen CS; Hansen LT; Fugger K; Lundin C; Johansson F; Helleday T; Sehested M; Lukas J; Bartek J
    Mol Cell Biol; 2005 May; 25(9):3553-62. PubMed ID: 15831461
    [TBL] [Abstract][Full Text] [Related]  

  • 6. N-methyl-N'-nitro-N-nitrosoguanidine activates cell-cycle arrest through distinct mechanisms activated in a dose-dependent manner.
    Beardsley DI; Kim WJ; Brown KD
    Mol Pharmacol; 2005 Oct; 68(4):1049-60. PubMed ID: 15994368
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Cadmium-induced DNA damage triggers G(2)/M arrest via chk1/2 and cdc2 in p53-deficient kidney proximal tubule cells.
    Bork U; Lee WK; Kuchler A; Dittmar T; Thévenod F
    Am J Physiol Renal Physiol; 2010 Feb; 298(2):F255-65. PubMed ID: 19923412
    [TBL] [Abstract][Full Text] [Related]  

  • 8. MSH2 and ATR form a signaling module and regulate two branches of the damage response to DNA methylation.
    Wang Y; Qin J
    Proc Natl Acad Sci U S A; 2003 Dec; 100(26):15387-92. PubMed ID: 14657349
    [TBL] [Abstract][Full Text] [Related]  

  • 9. ATR kinase activation mediated by MutSalpha and MutLalpha in response to cytotoxic O6-methylguanine adducts.
    Yoshioka K; Yoshioka Y; Hsieh P
    Mol Cell; 2006 May; 22(4):501-10. PubMed ID: 16713580
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Bifunctional DNA alkylator 1,3-bis(2-chloroethyl)-1-nitrosourea activates the ATR-Chk1 pathway independently of the mismatch repair pathway.
    Cui B; Johnson SP; Bullock N; Ali-Osman F; Bigner DD; Friedman HS
    Mol Pharmacol; 2009 Jun; 75(6):1356-63. PubMed ID: 19261750
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Role of c-Abl kinase in DNA mismatch repair-dependent G2 cell cycle checkpoint arrest responses.
    Wagner MW; Li LS; Morales JC; Galindo CL; Garner HR; Bornmann WG; Boothman DA
    J Biol Chem; 2008 Aug; 283(31):21382-93. PubMed ID: 18480061
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Interactions of human mismatch repair proteins MutSalpha and MutLalpha with proteins of the ATR-Chk1 pathway.
    Liu Y; Fang Y; Shao H; Lindsey-Boltz L; Sancar A; Modrich P
    J Biol Chem; 2010 Feb; 285(8):5974-82. PubMed ID: 20029092
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Distinct roles for DNA-PK, ATM and ATR in RPA phosphorylation and checkpoint activation in response to replication stress.
    Liu S; Opiyo SO; Manthey K; Glanzer JG; Ashley AK; Amerin C; Troksa K; Shrivastav M; Nickoloff JA; Oakley GG
    Nucleic Acids Res; 2012 Nov; 40(21):10780-94. PubMed ID: 22977173
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Mismatch repair-mediated G2/M arrest by 6-thioguanine involves the ATR-Chk1 pathway.
    Yamane K; Taylor K; Kinsella TJ
    Biochem Biophys Res Commun; 2004 May; 318(1):297-302. PubMed ID: 15110787
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The alkylating carcinogen N-methyl-N'-nitro-N-nitrosoguanidine activates the plasminogen activator inhibitor-1 gene through sequential phosphorylation of p53 by ATM and ATR kinases.
    Vidal B; Parra M; Jardí M; Saito S; Appella E; Muñoz-Cánoves P
    Thromb Haemost; 2005 Mar; 93(3):584-91. PubMed ID: 15735814
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Dissecting cellular responses to irradiation via targeted disruptions of the ATM-CHK1-PP2A circuit.
    Palii SS; Cui Y; Innes CL; Paules RS
    Cell Cycle; 2013 Apr; 12(7):1105-18. PubMed ID: 23462183
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Exonuclease 1 (Exo1) is required for activating response to S(N)1 DNA methylating agents.
    Izumchenko E; Saydi J; Brown KD
    DNA Repair (Amst); 2012 Dec; 11(12):951-64. PubMed ID: 23062884
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Carcinogen-induced S-phase arrest is Chk1 mediated and caffeine sensitive.
    Guo N; Faller DV; Vaziri C
    Cell Growth Differ; 2002 Feb; 13(2):77-86. PubMed ID: 11864911
    [TBL] [Abstract][Full Text] [Related]  

  • 19. High doses of SN1 type methylating agents activate DNA damage signaling cascades that are largely independent of mismatch repair.
    Stojic L; Cejka P; Jiricny J
    Cell Cycle; 2005 Mar; 4(3):473-7. PubMed ID: 15684614
    [TBL] [Abstract][Full Text] [Related]  

  • 20. p53-deficient cells rely on ATM- and ATR-mediated checkpoint signaling through the p38MAPK/MK2 pathway for survival after DNA damage.
    Reinhardt HC; Aslanian AS; Lees JA; Yaffe MB
    Cancer Cell; 2007 Feb; 11(2):175-89. PubMed ID: 17292828
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.