BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

375 related articles for article (PubMed ID: 15175893)

  • 21. Differential regulation of hepatic CYP2B6 and CYP3A4 genes by constitutive androstane receptor but not pregnane X receptor.
    Faucette SR; Sueyoshi T; Smith CM; Negishi M; Lecluyse EL; Wang H
    J Pharmacol Exp Ther; 2006 Jun; 317(3):1200-9. PubMed ID: 16513849
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Evaluation of 170 xenobiotics as transactivators of human pregnane X receptor (hPXR) and correlation to known CYP3A4 drug interactions.
    Sinz M; Kim S; Zhu Z; Chen T; Anthony M; Dickinson K; Rodrigues AD
    Curr Drug Metab; 2006 May; 7(4):375-88. PubMed ID: 16724927
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Simultaneous assessment of cytochrome P450 activity in cultured human hepatocytes for compound-mediated induction of CYP3A4, CYP2B6, and CYP1A2.
    Rhodes SP; Otten JN; Hingorani GP; Hartley DP; Franklin RB
    J Pharmacol Toxicol Methods; 2011; 63(3):223-6. PubMed ID: 21111054
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Impact of ritonavir, atazanavir and their combination on the CYP3A4 induction potential of efavirenz in primary human hepatocytes.
    Mugundu GM; Hariparsad N; Desai PB
    Drug Metab Lett; 2010 Jan; 4(1):45-50. PubMed ID: 20201776
    [TBL] [Abstract][Full Text] [Related]  

  • 25. In Vitro Approaches to Study Regulation of Hepatic Cytochrome P450 (CYP) 3A Expression by Paclitaxel and Rifampicin.
    Ghose R; Mallick P; Taneja G; Chu C; Moorthy B
    Methods Mol Biol; 2016; 1395():55-68. PubMed ID: 26910068
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Photochemotherapeutic agent 8-methoxypsoralen induces cytochrome P450 3A4 and carboxylesterase HCE2: evidence on an involvement of the pregnane X receptor.
    Yang J; Yan B
    Toxicol Sci; 2007 Jan; 95(1):13-22. PubMed ID: 17003103
    [TBL] [Abstract][Full Text] [Related]  

  • 27. The orphan nuclear receptor HNF4alpha determines PXR- and CAR-mediated xenobiotic induction of CYP3A4.
    Tirona RG; Lee W; Leake BF; Lan LB; Cline CB; Lamba V; Parviz F; Duncan SA; Inoue Y; Gonzalez FJ; Schuetz EG; Kim RB
    Nat Med; 2003 Feb; 9(2):220-4. PubMed ID: 12514743
    [TBL] [Abstract][Full Text] [Related]  

  • 28. A PXR reporter gene assay in a stable cell culture system: CYP3A4 and CYP2B6 induction by pesticides.
    Lemaire G; de Sousa G; Rahmani R
    Biochem Pharmacol; 2004 Dec; 68(12):2347-58. PubMed ID: 15548381
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Induction of cytochrome P450 3A4 and P-glycoprotein by the isoxazolyl-penicillin antibiotic flucloxacillin.
    Huwyler J; Wright MB; Gutmann H; Drewe J
    Curr Drug Metab; 2006 Feb; 7(2):119-26. PubMed ID: 16472102
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Regulation of the CYP3A4 gene by hydrocortisone and xenobiotics: role of the glucocorticoid and pregnane X receptors.
    El-Sankary W; Plant NJ; Gibson GG; Moore DJ
    Drug Metab Dispos; 2000 May; 28(5):493-6. PubMed ID: 10772626
    [TBL] [Abstract][Full Text] [Related]  

  • 31. The mycoestrogen zearalenone induces CYP3A through activation of the pregnane X receptor.
    Ding X; Lichti K; Staudinger JL
    Toxicol Sci; 2006 Jun; 91(2):448-55. PubMed ID: 16547076
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Clinically Relevant Cytochrome P450 3A4 Induction Mechanisms and Drug Screening in Three-Dimensional Spheroid Cultures of Primary Human Hepatocytes.
    Hendriks DFG; Vorrink SU; Smutny T; Sim SC; Nordling Å; Ullah S; Kumondai M; Jones BC; Johansson I; Andersson TB; Lauschke VM; Ingelman-Sundberg M
    Clin Pharmacol Ther; 2020 Oct; 108(4):844-855. PubMed ID: 32320483
    [TBL] [Abstract][Full Text] [Related]  

  • 33. A double transgenic mouse model expressing human pregnane X receptor and cytochrome P450 3A4.
    Ma X; Cheung C; Krausz KW; Shah YM; Wang T; Idle JR; Gonzalez FJ
    Drug Metab Dispos; 2008 Dec; 36(12):2506-12. PubMed ID: 18799805
    [TBL] [Abstract][Full Text] [Related]  

  • 34. The use of human hepatocyte cultures to study the induction of cytochrome P-450.
    Kostrubsky VE; Ramachandran V; Venkataramanan R; Dorko K; Esplen JE; Zhang S; Sinclair JF; Wrighton SA; Strom SC
    Drug Metab Dispos; 1999 Aug; 27(8):887-94. PubMed ID: 10421615
    [TBL] [Abstract][Full Text] [Related]  

  • 35. A cell-based reporter gene assay for determining induction of CYP3A4 in a high-volume system.
    Raucy J; Warfe L; Yueh MF; Allen SW
    J Pharmacol Exp Ther; 2002 Oct; 303(1):412-23. PubMed ID: 12235278
    [TBL] [Abstract][Full Text] [Related]  

  • 36. CYP3A induction by liver x receptor ligands in primary cultured rat and mouse hepatocytes is mediated by the pregnane X receptor.
    Shenoy SD; Spencer TA; Mercer-Haines NA; Alipour M; Gargano MD; Runge-Morris M; Kocarek TA
    Drug Metab Dispos; 2004 Jan; 32(1):66-71. PubMed ID: 14709622
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Selective induction of human hepatic cytochromes P450 2B6 and 3A4 by metamizole.
    Saussele T; Burk O; Blievernicht JK; Klein K; Nussler A; Nussler N; Hengstler JG; Eichelbaum M; Schwab M; Zanger UM
    Clin Pharmacol Ther; 2007 Sep; 82(3):265-74. PubMed ID: 17344806
    [TBL] [Abstract][Full Text] [Related]  

  • 38. MDR1 genotype is associated with hepatic cytochrome P450 3A4 basal and induction phenotype.
    Lamba J; Strom S; Venkataramanan R; Thummel KE; Lin YS; Liu W; Cheng C; Lamba V; Watkins PB; Schuetz E
    Clin Pharmacol Ther; 2006 Apr; 79(4):325-38. PubMed ID: 16580901
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Effect of the adrenal 11-beta-hydroxylase inhibitor metyrapone on human hepatic cytochrome P-450 expression: induction of cytochrome P-450 3A4.
    Harvey JL; Paine AJ; Maurel P; Wright MC
    Drug Metab Dispos; 2000 Jan; 28(1):96-101. PubMed ID: 10611146
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Dual effect of dexamethasone on CYP3A4 gene expression in human hepatocytes. Sequential role of glucocorticoid receptor and pregnane X receptor.
    Pascussi JM; Drocourt L; Gerbal-Chaloin S; Fabre JM; Maurel P; Vilarem MJ
    Eur J Biochem; 2001 Dec; 268(24):6346-58. PubMed ID: 11737189
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 19.