BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

200 related articles for article (PubMed ID: 15177039)

  • 1. The isoflavonoids genistein and quercetin activate different stress signaling pathways as shown by analysis of site-specific phosphorylation of ATM, p53 and histone H2AX.
    Ye R; Goodarzi AA; Kurz EU; Saito S; Higashimoto Y; Lavin MF; Appella E; Anderson CW; Lees-Miller SP
    DNA Repair (Amst); 2004 Mar; 3(3):235-44. PubMed ID: 15177039
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Constitutive phosphorylation of ATM in lymphoblastoid cell lines from patients with ICF syndrome without downstream kinase activity.
    Goldstine JV; Nahas S; Gamo K; Gartler SM; Hansen RS; Roelfsema JH; Gatti RA; Marahrens Y
    DNA Repair (Amst); 2006 Apr; 5(4):432-43. PubMed ID: 16426903
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Induction of ATF3 by ionizing radiation is mediated via a signaling pathway that includes ATM, Nibrin1, stress-induced MAPkinases and ATF-2.
    Kool J; Hamdi M; Cornelissen-Steijger P; van der Eb AJ; Terleth C; van Dam H
    Oncogene; 2003 Jul; 22(27):4235-42. PubMed ID: 12833146
    [TBL] [Abstract][Full Text] [Related]  

  • 4. E2F1 uses the ATM signaling pathway to induce p53 and Chk2 phosphorylation and apoptosis.
    Powers JT; Hong S; Mayhew CN; Rogers PM; Knudsen ES; Johnson DG
    Mol Cancer Res; 2004 Apr; 2(4):203-14. PubMed ID: 15140942
    [TBL] [Abstract][Full Text] [Related]  

  • 5. DNA damage-induced activation of ATM and ATM-dependent signaling pathways.
    Kurz EU; Lees-Miller SP
    DNA Repair (Amst); 2004; 3(8-9):889-900. PubMed ID: 15279774
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Ionizing radiation activates the ATM kinase throughout the cell cycle.
    Pandita TK; Lieberman HB; Lim DS; Dhar S; Zheng W; Taya Y; Kastan MB
    Oncogene; 2000 Mar; 19(11):1386-91. PubMed ID: 10723129
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Homeodomain-interacting protein kinase 2 is the ionizing radiation-activated p53 serine 46 kinase and is regulated by ATM.
    Dauth I; Krüger J; Hofmann TG
    Cancer Res; 2007 Mar; 67(5):2274-9. PubMed ID: 17332358
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Regulation of the IRF-1 tumour modifier during the response to genotoxic stress involves an ATM-dependent signalling pathway.
    Pamment J; Ramsay E; Kelleher M; Dornan D; Ball KL
    Oncogene; 2002 Nov; 21(51):7776-85. PubMed ID: 12420214
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Gallic acid induces apoptosis of lung fibroblasts via a reactive oxygen species-dependent ataxia telangiectasia mutated-p53 activation pathway.
    Chuang CY; Liu HC; Wu LC; Chen CY; Chang JT; Hsu SL
    J Agric Food Chem; 2010 Mar; 58(5):2943-51. PubMed ID: 20151649
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Arecoline-induced phosphorylated p53 and p21(WAF1) protein expression is dependent on ATM/ATR and phosphatidylinositol-3-kinase in clone-9 cells.
    Chou WW; Guh JY; Tsai JF; Hwang CC; Chiou SJ; Chuang LY
    J Cell Biochem; 2009 Jun; 107(3):408-17. PubMed ID: 19343784
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Activation of p53 transcriptional activity requires ATM's kinase domain and multiple N-terminal serine residues of p53.
    Turenne GA; Paul P; Laflair L; Price BD
    Oncogene; 2001 Aug; 20(37):5100-10. PubMed ID: 11526498
    [TBL] [Abstract][Full Text] [Related]  

  • 12. ATM associates with and phosphorylates p53: mapping the region of interaction.
    Khanna KK; Keating KE; Kozlov S; Scott S; Gatei M; Hobson K; Taya Y; Gabrielli B; Chan D; Lees-Miller SP; Lavin MF
    Nat Genet; 1998 Dec; 20(4):398-400. PubMed ID: 9843217
    [TBL] [Abstract][Full Text] [Related]  

  • 13. ATM-dependent activation of p53 involves dephosphorylation and association with 14-3-3 proteins.
    Waterman MJ; Stavridi ES; Waterman JL; Halazonetis TD
    Nat Genet; 1998 Jun; 19(2):175-8. PubMed ID: 9620776
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Chronic doxorubicin cardiotoxicity is mediated by oxidative DNA damage-ATM-p53-apoptosis pathway and attenuated by pitavastatin through the inhibition of Rac1 activity.
    Yoshida M; Shiojima I; Ikeda H; Komuro I
    J Mol Cell Cardiol; 2009 Nov; 47(5):698-705. PubMed ID: 19660469
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Enhanced phosphorylation of p53 serine 18 following DNA damage in DNA-dependent protein kinase catalytic subunit-deficient cells.
    Araki R; Fukumura R; Fujimori A; Taya Y; Shiloh Y; Kurimasa A; Burma S; Li GC; Chen DJ; Sato K; Hoki Y; Tatsumi K; Abe M
    Cancer Res; 1999 Aug; 59(15):3543-6. PubMed ID: 10446957
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Role for ATM in DNA damage-induced phosphorylation of BRCA1.
    Gatei M; Scott SP; Filippovitch I; Soronika N; Lavin MF; Weber B; Khanna KK
    Cancer Res; 2000 Jun; 60(12):3299-304. PubMed ID: 10866324
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Polo-like kinase 1 inactivation following mitotic DNA damaging treatments is independent of ataxia telangiectasia mutated kinase.
    Yuan JH; Feng Y; Fisher RH; Maloid S; Longo DL; Ferris DK
    Mol Cancer Res; 2004 Jul; 2(7):417-26. PubMed ID: 15280449
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Doxorubicin activates ATM-dependent phosphorylation of multiple downstream targets in part through the generation of reactive oxygen species.
    Kurz EU; Douglas P; Lees-Miller SP
    J Biol Chem; 2004 Dec; 279(51):53272-81. PubMed ID: 15489221
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Both ERK1 and ERK2 kinases promote G2/M arrest in etoposide-treated MCF7 cells by facilitating ATM activation.
    Wei F; Xie Y; Tao L; Tang D
    Cell Signal; 2010 Nov; 22(11):1783-9. PubMed ID: 20637859
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Pharmacologic manipulation of the ataxia-telangiectasia mutated gene product as an intervention in age-related disease.
    Shackelford RE
    Med Hypotheses; 2005; 65(2):363-9. PubMed ID: 15922113
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.