BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

661 related articles for article (PubMed ID: 15177047)

  • 1. A role for DNA polymerase V in G --> T mutations from the major benzo[a]pyrene N2-dG adduct when studied in a 5'-TGT sequence in E. coli.
    Yin J; Seo KY; Loechler EL
    DNA Repair (Amst); 2004 Mar; 3(3):323-34. PubMed ID: 15177047
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Mirror image stereoisomers of the major benzo[a]pyrene N2-dG adduct are bypassed by different lesion-bypass DNA polymerases in E. coli.
    Seo KY; Nagalingam A; Miri S; Yin J; Chandani S; Kolbanovskiy A; Shastry A; Loechler EL
    DNA Repair (Amst); 2006 Apr; 5(4):515-22. PubMed ID: 16483853
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Mutagenesis studies with four stereoisomeric N2-dG benzo[a]pyrene adducts in the identical 5'-CGC sequence used in NMR studies: G->T mutations dominate in each case.
    Seo KY; Nagalingam A; Tiffany M; Loechler EL
    Mutagenesis; 2005 Nov; 20(6):441-8. PubMed ID: 16311255
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Free-energy perturbation methods to study structure and energetics of DNA adducts: results for the major N2-dG adduct of benzo[a]pyrene in two conformations and different sequence contexts.
    Chandani S; Lee CH; Loechler EL
    Chem Res Toxicol; 2005 Jul; 18(7):1108-23. PubMed ID: 16022503
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Mutagenesis studies of the major benzo[a]pyrene N2-dG adduct in a 5'-TG versus a 5'-UG sequence: removal of the methyl group causes a modest decrease in the [G->T/G->A] mutational ratio.
    Nagalingam A; Seo KY; Loechler EL
    Mutagenesis; 2005 Mar; 20(2):105-10. PubMed ID: 15755802
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The major, N2-dG adduct of (+)-anti-B[a]PDE shows a dramatically different mutagenic specificity (predominantly, G --> A) in a 5'-CGT-3' sequence context.
    Shukla R; Liu T; Geacintov NE; Loechler EL
    Biochemistry; 1997 Aug; 36(33):10256-61. PubMed ID: 9254624
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Homology modeling of four Y-family, lesion-bypass DNA polymerases: the case that E. coli Pol IV and human Pol kappa are orthologs, and E. coli Pol V and human Pol eta are orthologs.
    Lee CH; Chandani S; Loechler EL
    J Mol Graph Model; 2006 Sep; 25(1):87-102. PubMed ID: 16386932
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Targeted A --> T and G --> T mutations induced by site-specific deoxyadenosine and deoxyguanosine adducts, respectively, from the (+)-anti-diol epoxide of dibenz[a,j]anthracene in M13mp7L2.
    Min Z; Gill RD; Cortez C; Harvey RG; Loechler EL; DiGiovanni J
    Biochemistry; 1996 Apr; 35(13):4128-38. PubMed ID: 8672448
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The major, N2-dG adduct of (+)-anti-B[a]PDE induces G-->A mutations in a 5'-AGA-3' sequence context.
    Shukla R; Geacintov NE; Loechler EL
    Carcinogenesis; 1999 Feb; 20(2):261-8. PubMed ID: 10069463
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Effect of SOS-induced Pol II, Pol IV, and Pol V DNA polymerases on UV-induced mutagenesis and MFD repair in Escherichia coli cells.
    Wrzesiński M; Nowosielska A; Nieminuszczy J; Grzesiuk E
    Acta Biochim Pol; 2005; 52(1):139-47. PubMed ID: 15827613
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Mutagenic properties of 3-(deoxyguanosin-N2-yl)-2-acetylaminofluorene, a persistent acetylaminofluorene-derived DNA adduct in mammalian cells.
    Yasui M; Dong H; Bonala RR; Suzuki N; Ohmori H; Hanaoka F; Johnson F; Grollman AP; Shibutani S
    Biochemistry; 2004 Nov; 43(47):15005-13. PubMed ID: 15554708
    [TBL] [Abstract][Full Text] [Related]  

  • 12. How stereochemistry affects mutagenesis by N2-deoxyguanosine adducts of 7,8-dihydroxy-9,10-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene: configuration of the adduct bond is more important than those of the hydroxyl groups.
    Shukla R; Jelinsky S; Liu T; Geacintov NE; Loechler EL
    Biochemistry; 1997 Oct; 36(43):13263-9. PubMed ID: 9341216
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Misincorporation of nucleotides opposite five-membered exocyclic ring guanine derivatives by escherichia coli polymerases in vitro and in vivo: 1,N2-ethenoguanine, 5,6,7,9-tetrahydro-9-oxoimidazo[1, 2-a]purine, and 5,6,7,9-tetrahydro-7-hydroxy-9-oxoimidazo[1, 2-a]purine.
    Langouët S; Mican AN; Müller M; Fink SP; Marnett LJ; Muhle SA; Guengerich FP
    Biochemistry; 1998 Apr; 37(15):5184-93. PubMed ID: 9548749
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Mutagenic potential of stereoisomeric bay region (+)- and (-)-cis-anti-benzo[a]pyrene diol epoxide-N2-2'-deoxyguanosine adducts in Escherichia coli and simian kidney cells.
    Fernandes A; Liu T; Amin S; Geacintov NE; Grollman AP; Moriya M
    Biochemistry; 1998 Jul; 37(28):10164-72. PubMed ID: 9665722
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Molecular modeling benzo[a]pyrene N2-dG adducts in the two overlapping active sites of the Y-family DNA polymerase Dpo4.
    Chandani S; Loechler EL
    J Mol Graph Model; 2007 Jan; 25(5):658-70. PubMed ID: 16782374
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Y-Family DNA polymerases may use two different dNTP shapes for insertion: a hypothesis and its implications.
    Chandani S; Loechler EL
    J Mol Graph Model; 2009 Apr; 27(7):759-69. PubMed ID: 19188081
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Specificity of replicative and SOS-inducible DNA polymerases in frameshift mutagenesis: mutability of Salmonella typhimurium strains overexpressing SOS-inducible DNA polymerases to 30 chemical mutagens.
    Matsui K; Yamada M; Imai M; Yamamoto K; Nohmi T
    DNA Repair (Amst); 2006 Apr; 5(4):465-78. PubMed ID: 16455311
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Molecular modeling of the major benzo[a]pyrene N2-dG adduct in cases where mutagenesis results are known in double stranded DNA.
    Lee CH; Loechler EL
    Mutat Res; 2003 Aug; 529(1-2):59-76. PubMed ID: 12943920
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Mutagenic effects of 2-deoxyribonolactone in Escherichia coli. An abasic lesion that disobeys the A-rule.
    Kroeger KM; Jiang YL; Kow YW; Goodman MF; Greenberg MM
    Biochemistry; 2004 Jun; 43(21):6723-33. PubMed ID: 15157106
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Translesion synthesis in Escherichia coli: lessons from the NarI mutation hot spot.
    Fuchs RP; Fujii S
    DNA Repair (Amst); 2007 Jul; 6(7):1032-41. PubMed ID: 17403618
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 34.