BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

361 related articles for article (PubMed ID: 15177184)

  • 1. Biochemical characterization of the ataxia-telangiectasia mutated (ATM) protein from human cells.
    Goodarzi AA; Lees-Miller SP
    DNA Repair (Amst); 2004 Jul; 3(7):753-67. PubMed ID: 15177184
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Replication protein A2 phosphorylation after DNA damage by the coordinated action of ataxia telangiectasia-mutated and DNA-dependent protein kinase.
    Wang H; Guan J; Wang H; Perrault AR; Wang Y; Iliakis G
    Cancer Res; 2001 Dec; 61(23):8554-63. PubMed ID: 11731442
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Purification and characterization of ATM from human placenta. A manganese-dependent, wortmannin-sensitive serine/threonine protein kinase.
    Chan DW; Son SC; Block W; Ye R; Khanna KK; Wold MS; Douglas P; Goodarzi AA; Pelley J; Taya Y; Lavin MF; Lees-Miller SP
    J Biol Chem; 2000 Mar; 275(11):7803-10. PubMed ID: 10713094
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Role of autophagy in chemoresistance: regulation of the ATM-mediated DNA-damage signaling pathway through activation of DNA-PKcs and PARP-1.
    Yoon JH; Ahn SG; Lee BH; Jung SH; Oh SH
    Biochem Pharmacol; 2012 Mar; 83(6):747-57. PubMed ID: 22226932
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Ionizing radiation induces ataxia telangiectasia mutated kinase (ATM)-mediated phosphorylation of LKB1/STK11 at Thr-366.
    Sapkota GP; Deak M; Kieloch A; Morrice N; Goodarzi AA; Smythe C; Shiloh Y; Lees-Miller SP; Alessi DR
    Biochem J; 2002 Dec; 368(Pt 2):507-16. PubMed ID: 12234250
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Ataxia telangiectasia mutated (ATM) is dispensable for endonuclease I-SceI-induced homologous recombination in mouse embryonic stem cells.
    Rass E; Chandramouly G; Zha S; Alt FW; Xie A
    J Biol Chem; 2013 Mar; 288(10):7086-95. PubMed ID: 23355489
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Doxorubicin activates ATM-dependent phosphorylation of multiple downstream targets in part through the generation of reactive oxygen species.
    Kurz EU; Douglas P; Lees-Miller SP
    J Biol Chem; 2004 Dec; 279(51):53272-81. PubMed ID: 15489221
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Constitutive phosphorylation of ATM in lymphoblastoid cell lines from patients with ICF syndrome without downstream kinase activity.
    Goldstine JV; Nahas S; Gamo K; Gartler SM; Hansen RS; Roelfsema JH; Gatti RA; Marahrens Y
    DNA Repair (Amst); 2006 Apr; 5(4):432-43. PubMed ID: 16426903
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Suppression of Tousled-like kinase activity after DNA damage or replication block requires ATM, NBS1 and Chk1.
    Krause DR; Jonnalagadda JC; Gatei MH; Sillje HH; Zhou BB; Nigg EA; Khanna K
    Oncogene; 2003 Sep; 22(38):5927-37. PubMed ID: 12955071
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Identification and characterization of a novel and specific inhibitor of the ataxia-telangiectasia mutated kinase ATM.
    Hickson I; Zhao Y; Richardson CJ; Green SJ; Martin NM; Orr AI; Reaper PM; Jackson SP; Curtin NJ; Smith GC
    Cancer Res; 2004 Dec; 64(24):9152-9. PubMed ID: 15604286
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Enhanced phosphorylation of transcription factor sp1 in response to herpes simplex virus type 1 infection is dependent on the ataxia telangiectasia-mutated protein.
    Iwahori S; Shirata N; Kawaguchi Y; Weller SK; Sato Y; Kudoh A; Nakayama S; Isomura H; Tsurumi T
    J Virol; 2007 Sep; 81(18):9653-64. PubMed ID: 17609267
    [TBL] [Abstract][Full Text] [Related]  

  • 12. ATM: the protein encoded by the gene mutated in the radiosensitive syndrome ataxia-telangiectasia.
    Lavin MF; Khanna KK
    Int J Radiat Biol; 1999 Oct; 75(10):1201-14. PubMed ID: 10549596
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Autophosphorylation of ataxia-telangiectasia mutated is regulated by protein phosphatase 2A.
    Goodarzi AA; Jonnalagadda JC; Douglas P; Young D; Ye R; Moorhead GB; Lees-Miller SP; Khanna KK
    EMBO J; 2004 Nov; 23(22):4451-61. PubMed ID: 15510216
    [TBL] [Abstract][Full Text] [Related]  

  • 14. ATM mediates repression of DNA end-degradation in an ATP-dependent manner.
    Rahal EA; Henricksen LA; Li Y; Turchi JJ; Pawelczak KS; Dixon K
    DNA Repair (Amst); 2008 Mar; 7(3):464-75. PubMed ID: 18207464
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Telomeric protein Pin2/TRF1 as an important ATM target in response to double strand DNA breaks.
    Kishi S; Zhou XZ; Ziv Y; Khoo C; Hill DE; Shiloh Y; Lu KP
    J Biol Chem; 2001 Aug; 276(31):29282-91. PubMed ID: 11375976
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Ataxia telangiectasia mutated (ATM) signaling network is modulated by a novel poly(ADP-ribose)-dependent pathway in the early response to DNA-damaging agents.
    Haince JF; Kozlov S; Dawson VL; Dawson TM; Hendzel MJ; Lavin MF; Poirier GG
    J Biol Chem; 2007 Jun; 282(22):16441-53. PubMed ID: 17428792
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Roles of DNA-dependent protein kinase and ATM in cell-cycle-dependent radiation sensitivity in human cells.
    Yoshida M; Hosoi Y; Miyachi H; Ishii N; Matsumoto Y; Enomoto A; Nakagawa K; Yamada S; Suzuki N; Ono T
    Int J Radiat Biol; 2002 Jun; 78(6):503-12. PubMed ID: 12065055
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Purification and DNA binding properties of the ataxia-telangiectasia gene product ATM.
    Smith GC; Cary RB; Lakin ND; Hann BC; Teo SH; Chen DJ; Jackson SP
    Proc Natl Acad Sci U S A; 1999 Sep; 96(20):11134-9. PubMed ID: 10500142
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Activation of the S phase DNA damage checkpoint by mitomycin C.
    Mladenov E; Tsaneva I; Anachkova B
    J Cell Physiol; 2007 May; 211(2):468-76. PubMed ID: 17167777
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Inhibition of poly(ADP-ribose) polymerase (PARP) and ataxia telangiectasia mutated (ATM) on the chemosensitivity of mantle cell lymphoma to agents that induce DNA strand breaks.
    Golla RM; Li M; Shen Y; Ji M; Yan Y; Fu K; Greiner TC; McKeithan TW; Chan WC
    Hematol Oncol; 2012 Dec; 30(4):175-9. PubMed ID: 22170260
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 19.